Deletion of BCATm increases insulin-stimulated glucose oxidation in the heart
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Deletion of BCATm increases insulin-stimulated glucose oxidation in the heart
Authors
Keywords
Branched chain amino acids, Branched chain keto acids, Mitochondrial branched chain aminotransferase, Metabolism, Cardiac insulin signaling, Glucose oxidation
Journal
METABOLISM-CLINICAL AND EXPERIMENTAL
Volume 124, Issue -, Pages 154871
Publisher
Elsevier BV
Online
2021-09-01
DOI
10.1016/j.metabol.2021.154871
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Branched-chain ketoacid overload inhibits insulin action in the muscle
- (2020) Dipsikha Biswas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Insulin directly stimulates mitochondrial glucose oxidation in the heart
- (2020) Qutuba G. Karwi et al. Cardiovascular Diabetology
- Myocardial ketone body utilization in patients with heart failure: The impact of oral ketone ester
- (2020) Luca Monzo et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Targeting the glucagon receptor improves cardiac function and enhances insulin sensitivity following a myocardial infarction
- (2019) Qutuba G. Karwi et al. Cardiovascular Diabetology
- Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency
- (2019) Kim L Ho et al. CARDIOVASCULAR RESEARCH
- Weight Loss Enhances Cardiac Energy Metabolism and Function in Heart Failure Associated with Obesity
- (2019) Qutuba G Karwi et al. DIABETES OBESITY & METABOLISM
- Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure
- (2019) Golam M. Uddin et al. Cardiovascular Diabetology
- Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance
- (2019) Meiyi Zhou et al. DIABETES
- Therapeutic Effect of Targeting Branched‐Chain Amino Acid Catabolic Flux in Pressure‐Overload Induced Heart Failure
- (2019) Mengping Chen et al. Journal of the American Heart Association
- Adropin regulates cardiac energy metabolism and improves cardiac function and efficiency
- (2019) Tariq R. Altamimi et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake
- (2018) Lewin Small et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Branched-chain amino acids in health and disease: metabolism, alterations in blood plasma, and as supplements
- (2018) Milan Holeček Nutrition & Metabolism
- Cardiac Branched-Chain Amino Acid Oxidation is Reduced During Insulin Resistance in the Heart
- (2018) Natasha Fillmore et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Human Plasmablast Migration Toward CXCL12 Requires Glucose Oxidation by Enhanced Pyruvate Dehydrogenase Activity via AKT
- (2018) Hyo-Kyung Pak et al. Frontiers in Immunology
- Restoration of metabolic health by decreased consumption of branched-chain amino acids
- (2017) Nicole E. Cummings et al. JOURNAL OF PHYSIOLOGY-LONDON
- Repletion of branched chain amino acids reverses mTORC1 signaling but not improved metabolism during dietary protein dilution
- (2017) Adriano Maida et al. Molecular Metabolism
- Defective branched chain amino acid catabolism contributes to cardiac dysfunction and remodeling following myocardial infarction
- (2016) Wei Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Catabolic Defect of Branched-Chain Amino Acids Promotes Heart FailureCLINICAL PERSPECTIVE
- (2016) Haipeng Sun et al. CIRCULATION
- Head to Head Comparison of Short-Term Treatment with the NAD+ Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese Female Mice
- (2016) Golam M. Uddin et al. Frontiers in Pharmacology
- Effects of individual branched-chain amino acids deprivation on insulin sensitivity and glucose metabolism in mice
- (2014) Fei Xiao et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Branched-chain amino acids in metabolic signalling and insulin resistance
- (2014) Christopher J. Lynch et al. Nature Reviews Endocrinology
- ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4
- (2013) Jun Mori et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Quantification of branched-chain keto acids in tissue by ultra fast liquid chromatography–mass spectrometry
- (2013) Kristine C. Olson et al. ANALYTICAL BIOCHEMISTRY
- Cardiac Insulin-Resistance and Decreased Mitochondrial Energy Production Precede the Development of Systolic Heart Failure After Pressure-Overload Hypertrophy
- (2013) Liyan Zhang et al. Circulation-Heart Failure
- Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload
- (2012) Pavel Zhabyeyev et al. CARDIOVASCULAR RESEARCH
- Agonist-Induced Hypertrophy and Diastolic Dysfunction Are Associated With Selective Reduction in Glucose Oxidation
- (2012) Jun Mori et al. Circulation-Heart Failure
- Branched-chain amino acid metabolism in heart disease: an epiphenomenon or a real culprit?
- (2011) Y. Huang et al. CARDIOVASCULAR RESEARCH
- Transamination Is Required for α-Ketoisocaproate but Not Leucine to Stimulate Insulin Secretion
- (2010) Yingsheng Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sensitive and Rapid Method for Amino Acid Quantitation in Malaria Biological Samples Using AccQ•Tag Ultra Performance Liquid Chromatography-Electrospray Ionization-MS/MS with Multiple Reaction Monitoring
- (2009) Jenny M. Armenta et al. ANALYTICAL CHEMISTRY
- A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
- (2009) Christopher B. Newgard et al. Cell Metabolism
- Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells
- (2009) Gang Lu et al. JOURNAL OF CLINICAL INVESTIGATION
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started