Quercetin stimulates the non-amyloidogenic pathway via activation of ADAM10 and ADAM17 gene expression in aluminum chloride-induced Alzheimer's disease rat model

Quercetin is protective against short‐term dietary advanced glycation end products intake induced cognitive dysfunction in aged ICR mice

(2020) Shengyi Yang et al.   JOURNAL OF FOOD BIOCHEMISTRY

Short photoperiod restores ventral subicular lesion‐induced deficits in affective and socio‐cognitive behavior in male Wistar rats

(2020) Duttagupta Subhadeep et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Combination of Omega 3 and Coenzyme Q10 Exerts Neuroprotective Potential Against Hypercholesterolemia-Induced Alzheimer's-Like Disease in Rats

(2020) Ghadha Ibrahim Fouad   NEUROCHEMICAL RESEARCH

Neuroprotective effect of quercetin nanoparticles: A possible prophylactic and therapeutic role in alzheimer’s disease

(2020) Rehab Ahmed Rifaai et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Sesame oil mitigates memory impairment, oxidative stress, and neurodegeneration in a rat model of Alzheimer's disease. A pivotal role of NF-κB/p38MAPK/BDNF/PPAR-γ pathways

(2020) Eman A. Mohamed et al.   JOURNAL OF ETHNOPHARMACOLOGY

γ-Secretase Modulatory Proteins: The Guiding Hand Behind the Running Scissors

(2020) Eitan Wong et al.   Frontiers in Aging Neuroscience

Functions of ‘A disintegrin and metalloproteases (ADAMs)’ in the mammalian nervous system

(2019) Hung-En Hsia et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Quercetin Regulates the Integrated Stress Response to Improve Memory

(2019) Toshiyuki Nakagawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The neuropathological diagnosis of Alzheimer’s disease

(2019) Michael A. DeTure et al.   Molecular Neurodegeneration

Neurotransmitter Imbalance in the Brain and Alzheimer’s Disease Pathology

(2019) Stuart G. Snowden et al.   JOURNAL OF ALZHEIMERS DISEASE

Berberine alleviates amyloid-beta pathology in the brain of APP/PS1 transgenic mice via inhibiting β/γ-secretases activity and enhancing α-secretases

(2018) Zhiyou Cai et al.   Current Alzheimer Research

A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease

(2018) Daniela Hartl et al.   MOLECULAR PSYCHIATRY

Understanding Alzheimer Disease at the Interface between Genetics and Transcriptomics

(2018) Jan Verheijen et al.   TRENDS IN GENETICS

Acute aluminum chloride toxicity revisited: Study on DNA damage and histopathological, biochemical and neurochemical alterations in rat brain

(2018) Laraib Liaquat et al.   LIFE SCIENCES

Neuroprotective Effect of Quercetin Against the Detrimental Effects of LPS in the Adult Mouse Brain

(2018) Amjad Khan et al.   Frontiers in Pharmacology

Morus alba L. Diminishes visceral adiposity, insulin resistance, behavioral alterations via regulation of gene expression of leptin, resistin and adiponectin in rats fed a high-cholesterol diet

(2018) Fateheya Mohamed Metwally et al.   PHYSIOLOGY & BEHAVIOR

Optogenetic stimulation of dentate gyrus engrams restores memory in Alzheimer's disease mice

(2017) Jennifer N. Perusini et al.   HIPPOCAMPUS

Streptozotocin-induced hippocampal astrogliosis and insulin signaling malfunction as experimental scales for subclinical sporadic Alzheimer model

(2017) Farzaneh Rostami et al.   LIFE SCIENCES

Cutaneous Adverse Effects of Neurologic Medications

(2016) Eman Bahrani et al.   CNS DRUGS

Neuroprotective Effect of Nanodiamond in Alzheimer’s Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling

(2016) Shawqi H. Alawdi et al.   MOLECULAR NEUROBIOLOGY

Improvement of memory recall by quercetin in rodent contextual fear conditioning and human early-stage Alzheimer’s disease patients

(2016) Toshiyuki Nakagawa et al.   NEUROREPORT

Emerging drug targets for Aβand tau in Alzheimer's disease: a systematic review

(2015) Sophie West et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Current Practices in the Treatment of Alzheimer Disease: Where is the Evidence After the Phase III Trials?

(2015) Megan J. Ehret et al.   CLINICAL THERAPEUTICS

The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice

(2015) Angélica Maria Sabogal-Guáqueta et al.   NEUROPHARMACOLOGY

Effects of Long-Term Treatment with Quercetin on Cognition and Mitochondrial Function in a Mouse Model of Alzheimer’s Disease

(2014) Dong-Mei Wang et al.   NEUROCHEMICAL RESEARCH

Quercetin protects the impairment of memory and anxiogenic-like behavior in rats exposed to cadmium: Possible involvement of the acetylcholinesterase and Na+,K+-ATPase activities

(2014) Fátima H. Abdalla et al.   PHYSIOLOGY & BEHAVIOR

Design of a comprehensive Alzheimer’s disease clinic and research center in Spain to meet critical patient and family needs

(2013) Mercè Boada et al.   Alzheimers & Dementia

Neuroprotective effect of quercetin in ectoenzymes and acetylcholinesterase activities in cerebral cortex synaptosomes of cadmium-exposed rats

(2013) Fátima Husein Abdalla et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Investigation of the neuroprotective action of saffron (Crocus sativus L.) in aluminum-exposed adult mice through behavioral and neurobiochemical assessment

(2012) Zacharoula I. Linardaki et al.   FOOD AND CHEMICAL TOXICOLOGY

Pen-2 is dispensable for endoproteolysis of presenilin 1, and nicastrin-Aph subcomplex is important for both γ-secretase assembly and substrate recruitment

(2012) Guozhang Mao et al.   JOURNAL OF NEUROCHEMISTRY

Prolactin is a peripheral marker of manganese neurotoxicity

(2011) A.P. Marreilha dos Santos et al.   BRAIN RESEARCH

Neuroprotective effect ofManasamitra vatakamagainst aluminium induced cognitive impairment and oxidative damage in the cortex and hippocampus of rat brain

(2011) Sathiravada Veerasamy Thirunavukkarasu et al.   DRUG AND CHEMICAL TOXICOLOGY

ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons

(2010) Peer-Hendrik Kuhn et al.   EMBO JOURNAL

The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex

(2010) E. Jorissen et al.   JOURNAL OF NEUROSCIENCE

Cholinesterase inhibitory activities of some flavonoid derivatives and chosen xanthone and their molecular docking studies

(2009) Mahmud Tareq Hassan Khan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate α-secretase activity

(2009) Minji Kim et al.   HUMAN MOLECULAR GENETICS

Flavonols and flavones as BACE-1 inhibitors: Structure–activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features

(2008) Yoshiari Shimmyo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS