Effects of Long-Term Treatment with Quercetin on Cognition and Mitochondrial Function in a Mouse Model of Alzheimer’s Disease

Quercetin along with piperine prevents cognitive dysfunction, oxidative stress and neuro-inflammation associated with mouse model of chronic unpredictable stress

(2013) Puneet Rinwa et al.   ARCHIVES OF PHARMACAL RESEARCH

Red ginseng abrogates oxidative stress via mitochondria protection mediated by LKB1-AMPK pathway

(2013) Guang-Zhi Dong et al.   BMC Complementary and Alternative Medicine

Quercetin Protects Mouse Brain against Lead-Induced Neurotoxicity

(2013) Chan-Min Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cardiotrophin-1 (CTF1) ameliorates glucose-uptake defects and improves memory and learning deficits in a transgenic mouse model of Alzheimer's disease

(2013) Dongmei Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death

(2013) C Moran et al.   Cell Death & Disease

α-SNAP inhibits AMPK signaling to reduce mitochondrial biogenesis and dephosphorylates Thr172 in AMPKα in vitro

(2013) Lifu Wang et al.   Nature Communications

AMP Kinase Activation Mitigates Dopaminergic Dysfunction and Mitochondrial Abnormalities in Drosophila Models of Parkinson's Disease

(2012) C.-H. Ng et al.   JOURNAL OF NEUROSCIENCE

Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease

(2012) Saila Vepsäläinen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mitochondrial Dysfunction—A Pharmacological Target in Alzheimer's Disease

(2012) Gunter P. Eckert et al.   MOLECULAR NEUROBIOLOGY

Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death

(2012) Moon-Yong Cha et al.   PLoS One

Defective Leptin–AMP-Dependent Kinase Pathway Induces Nitric Oxide Release and Contributes to Mitochondrial Dysfunction and Obesity in ob/ob Mice

(2011) Paola V. Finocchietto et al.   ANTIOXIDANTS & REDOX SIGNALING

Insights into Mitochondrial Dysfunction: Aging, Amyloid-β, and Tau–A Deleterious Trio

(2011) Karen Schmitt et al.   ANTIOXIDANTS & REDOX SIGNALING

Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease

(2011) Wei Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Leptin boosts cellular metabolism by activating AMPK and the sirtuins to reduce tau phosphorylation and β-amyloid in neurons

(2011) Steven J. Greco et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer

(2011) D. Grahame Hardie   BIOCHEMICAL SOCIETY TRANSACTIONS

Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics

(2011) P. Hemachandra Reddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

miR-29c regulates BACE1 protein expression

(2011) Yuanyuan Zong et al.   BRAIN RESEARCH

Cognitive-Enhancing Effect of Quercetin in a Rat Model of Parkinson's Disease Induced by 6-Hydroxydopamine

(2011) Napatr Sriraksa et al.   Evidence-based Complementary and Alternative Medicine

Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse

(2011) Ayumi Takamura et al.   Molecular Neurodegeneration

Quercetin and rutin prevent scopolamine-induced memory impairment in zebrafish

(2010) S.K. Richetti et al.   BEHAVIOURAL BRAIN RESEARCH

Involvement of AMP-activated-protein-kinase (AMPK) in neuronal amyloidogenesis

(2010) Je-Seong Won et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effect of flavonoids on the Aβ(25-35)-phospholipid bilayers interaction

(2010) Annamaria Tedeschi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation

(2010) Valérie Vingtdeux et al.   FASEB JOURNAL

AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism

(2010) Valérie Vingtdeux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melatonin Potentiates the Neuroprotective Properties of Resveratrol Against Beta-Amyloid-Induced Neurodegeneration by Modulating AMP-Activated Protein Kinase Pathways

(2010) Kyoung Ja Kwon et al.   Journal of Clinical Neurology

Mitochondrial dysfunction as a cause of ageing

(2010) A. Trifunovic et al.   JOURNAL OF INTERNAL MEDICINE

Quercetin activates AMP-activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity

(2010) Jun Lu et al.   JOURNAL OF PATHOLOGY

AMPK-associated signaling to bridge the gap between fuel metabolism and hepatocyte viability

(2010) Yoon Mee Yang   WORLD JOURNAL OF GASTROENTEROLOGY

Memantine Improves Cognition and Reduces Alzheimer’s-Like Neuropathology in Transgenic Mice

(2009) Hilda Martinez-Coria et al.   AMERICAN JOURNAL OF PATHOLOGY

Spatial navigation testing discriminates two types of amnestic mild cognitive impairment

(2009) Jan Laczó et al.   BEHAVIOURAL BRAIN RESEARCH

Leptin regulates tau phosphorylation and amyloid through AMPK in neuronal cells

(2009) Steven J. Greco et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AMPK-mediated GSK3β inhibition by isoliquiritigenin contributes to protecting mitochondria against iron-catalyzed oxidative stress

(2009) Song Hwa Choi et al.   BIOCHEMICAL PHARMACOLOGY

Resveratrol Protects Mitochondria against Oxidative Stress through AMP-Activated Protein Kinase-Mediated Glycogen Synthase Kinase-3  Inhibition Downstream of Poly(ADP-ribose)polymerase-LKB1 Pathway

(2009) S. M. Shin et al.   MOLECULAR PHARMACOLOGY

Quercetin improves cognitive deficits in rats with chronic cerebral ischemia and inhibits voltage-dependent sodium channels in hippocampal CA1 pyramidal neurons

(2009) Y. Yao et al.   PHYTOTHERAPY RESEARCH

Upregulation of Mitochondrial Uncoupling Protein-2 by the AMP-Activated Protein Kinase in Endothelial Cells Attenuates Oxidative Stress in Diabetes

(2008) Z. Xie et al.   DIABETES

Protective effect of quercetin in primary neurons against Aβ(1–42): relevance to Alzheimer's disease

(2008) Mubeen Ahmad Ansari et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

(2008) Heng Du et al.   NATURE MEDICINE

Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice

(2008) S. Hauptmann et al.   NEUROBIOLOGY OF AGING

Protective effect of quercetin against ICV colchicine-induced cognitive dysfunctions and oxidative damage in rats

(2008) Anil Kumar et al.   PHYTOTHERAPY RESEARCH

Amyloid-  overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

(2008) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA