A dual apolipoprotein C-II mimetic–apolipoprotein C-III antagonist peptide lowers plasma triglycerides

Moving Targets

(2019) Lars E. Larsen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

BeStSel: a web server for accurate protein secondary structure prediction and fold recognition from the circular dichroism spectra

(2018) András Micsonai et al.   NUCLEIC ACIDS RESEARCH

High Triglycerides Are Associated With Increased Cardiovascular Events, Medical Costs, and Resource Use: A Real‐World Administrative Claims Analysis of Statin‐Treated Patients With High Residual Cardiovascular Risk

(2018) Peter P. Toth et al.   Journal of the American Heart Association

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

(2018) Derek Klarin et al.   NATURE GENETICS

Metabolism and proteomics of large and small dense LDL in combined hyperlipidemia: effects of rosuvastatin

(2017) Nuntakorn Thongtang et al.   JOURNAL OF LIPID RESEARCH

Very-Low-Density Lipoprotein–Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III

(2017) Raimund Pechlaner et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Hypertriglyceridemia and atherosclerosis

(2017) Jia Peng et al.   Lipids in Health and Disease

A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels

(2017) Sumeet A Khetarpal et al.   NATURE MEDICINE

Triglyceride-Rich Lipoproteins and Atherosclerotic Cardiovascular Disease

(2016) Børge G. Nordestgaard   CIRCULATION RESEARCH

ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors

(2016) Philip L.S.M. Gordts et al.   JOURNAL OF CLINICAL INVESTIGATION

The crucial roles of apolipoproteins E and C-III in apoB lipoprotein metabolism in normolipidemia and hypertriglyceridemia

(2015) Frank M. Sacks   CURRENT OPINION IN LIPIDOLOGY

Hypertriglyceridemia in the Genomic Era: A New Paradigm

(2015) Gary F. Lewis et al.   ENDOCRINE REVIEWS

A Pressure-dependent Model for the Regulation of Lipoprotein Lipase by Apolipoprotein C-II

(2015) Nathan L. Meyers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion

(2015) Yan Wang et al.   JOURNAL OF LIPID RESEARCH

Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia

(2015) Daniel Gaudet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Apolipoprotein C-III

(2015) Alison B. Kohan   Current Opinion in Endocrinology Diabetes and Obesity

Amyloid Triangles, Squares, and Loops of Apolipoprotein C-III

(2014) Michel de Messieres et al.   BIOCHEMISTRY

Targeting APOC3 in the Familial Chylomicronemia Syndrome

(2014) Daniel Gaudet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans

(2013) Mark J. Graham et al.   CIRCULATION RESEARCH

Accurate and efficient integration for molecular dynamics simulations at constant temperature and pressure

(2013) Ross A. Lippert et al.   JOURNAL OF CHEMICAL PHYSICS

Simulations of Anionic Lipid Membranes: Development of Interaction-Specific Ion Parameters and Validation Using NMR Data

(2013) Richard M. Venable et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

Diagnosis and Management of Type I and Type V Hyperlipoproteinemia

(2011) Takanari Gotoda et al.   Journal of Atherosclerosis and Thrombosis

5A Apolipoprotein Mimetic Peptide Promotes Cholesterol Efflux and Reduces Atherosclerosis in Mice

(2010) M. J. A. Amar et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Parallel increase of plasma apoproteins C-II and C-III in Type 2 diabetic patients

(2009) S. Béliard et al.   DIABETIC MEDICINE

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Gender-Specific Differences in the Kinetics of Nonfasting TRL, IDL, and LDL Apolipoprotein B-100 in Men and Premenopausal Women

(2008) Nirupa R. Matthan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection

(2008) T. I. Pollin et al.   SCIENCE

Structural and Thermodynamic Approach to Peptide Immunogenicity

(2008) Carlos J. Camacho et al.   PLoS Computational Biology