Emerging role of post-translational modifications in chronic kidney disease and cardiovascular disease

Frequency Modulated Translocational Oscillations of Nrf2 Mediate the Antioxidant Response Element Cytoprotective Transcriptional Response

(2015) Mingzhan Xue et al.   ANTIOXIDANTS & REDOX SIGNALING

Skin Autofluorescence Associates With Vascular Calcification in Chronic Kidney Disease

(2014) Angela Yee-Moon Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Evidence for an exclusive association of matrix metalloproteinase-9 with dysfunctional high-density lipoprotein: A novel finding

(2014) S. Sini et al.   ATHEROSCLEROSIS

Cationic peptides neutralize Ox-LDL, prevent its uptake by macrophages, and attenuate inflammatory response

(2014) Chandrakala Aluganti Narasimhulu et al.   ATHEROSCLEROSIS

Humans With Atherosclerosis Have Impaired ABCA1 Cholesterol Efflux and Enhanced High-Density Lipoprotein Oxidation by Myeloperoxidase

(2014) Baohai Shao et al.   CIRCULATION RESEARCH

Carbamylated low-density lipoprotein induces endothelial dysfunction

(2014) Thimoteus Speer et al.   EUROPEAN HEART JOURNAL

Risk Factors for Heart Failure in Patients With Type 2 Diabetes Mellitus and Stage 4 Chronic Kidney Disease Treated With Bardoxolone Methyl

(2014) Melanie P. Chin et al.   JOURNAL OF CARDIAC FAILURE

An abundant dysfunctional apolipoprotein A1 in human atheroma

(2014) Ying Huang et al.   NATURE MEDICINE

Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples

(2014) Naila Rabbani et al.   Nature Protocols

Association of plasma levels of soluble receptor for advanced glycation end products and risk of kidney disease: the Atherosclerosis Risk in Communities study

(2014) Casey M. Rebholz et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Arginine-directed glycation and decreased HDL plasma concentration and functionality

(2014) L Godfrey et al.   Nutrition & Diabetes

Highly-Sensitive Detection of Free Advanced Glycation End-Products by Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry with 2,4,6-Trinitrobenzene Sulfonate Derivatization

(2013) Chihiro Hashimoto et al.   ANALYTICAL CHEMISTRY

A Receptor-Based Bioadsorbent to Target Advanced Glycation End Products in Chronic Kidney Disease

(2013) Yangrong Zhang et al.   ARTIFICIAL ORGANS

Detection of oxidized and glycated proteins in clinical samples using mass spectrometry — A user's perspective

(2013) Paul J. Thornalley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Carbamoylation abrogates the antioxidant potential of hydrogen sulfide

(2013) Monika Praschberger et al.   BIOCHIMIE

Post-translational modification derived products (PTMDPs): toxins in chronic diseases?

(2013) Philippe Gillery et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

The effect of oxidation on the mechanical response and microstructure of porcine aortas

(2013) Elizabeth A. Stephen et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Usefulness of non-enzymatic post-translational modification derived products (PTMDPs) as biomarkers of chronic diseases

(2013) Philippe Gillery et al.   Journal of Proteomics

Protein glycation during aging and in cardiovascular disease

(2013) Andreas Simm   Journal of Proteomics

Protein Carbamylation Predicts Mortality in ESRD

(2013) R. A. Koeth et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Effect of Lipoic Acid on Cyanate Toxicity in Different Structures of the Rat Brain

(2013) Maria Sokołowska et al.   NEUROTOXICITY RESEARCH

Myeloperoxidase-Derived Chlorinating Species Induce Protein Carbamylation Through Decomposition of Thiocyanate and Urea: Novel Pathways Generating Dysfunctional High-Density Lipoprotein

(2012) Michael Holzer et al.   ANTIOXIDANTS & REDOX SIGNALING

Effects of amino acids and albumin on erythropoietin carbamoylation

(2012) Kyubok Jin   Clinical and Experimental Nephrology

First evaluation of Capillarys 2 Flex Piercing® (Sebia) as a new analyzer for HbA1c assay by capillary electrophoresis

(2012) Stéphane Jaisson et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Bardoxolone Methyl Decreases Megalin and Activates Nrf2 in the Kidney

(2012) S. A. Reisman et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

(2012) Angelika Bierhaus et al.   NATURE MEDICINE

Endonuclease G mediates endothelial cell death induced by carbamylated LDL

(2011) Eugene O. Apostolov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Quantification of plasma homocitrulline using hydrophilic interaction liquid chromatography (HILIC) coupled to tandem mass spectrometry

(2011) Stéphane Jaisson et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Multistep Ultrahigh Performance Liquid Chromatography/Tandem Mass Spectrometry Analysis for Untargeted Quantification of Glycating Activity and Identification of Most Relevant Glycation Products

(2011) Stefan Mittelmaier et al.   ANALYTICAL CHEMISTRY

Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

(2011) Mingzhan Xue et al.   BIOCHEMICAL JOURNAL

S-Carbamoylation impairs the oxidant scavenging activity of cysteine: Its possible impact on increased LDL modification in uraemia

(2011) Sabine M. Schreier et al.   BIOCHIMIE

Carbamylation-Derived Products: Bioactive Compounds and Potential Biomarkers in Chronic Renal Failure and Atherosclerosis

(2011) S. Jaisson et al.   CLINICAL CHEMISTRY

The Role of Nitric Oxide on Endothelial Function

(2011) Dimitris Tousoulis et al.   Current Vascular Pharmacology

Effects of alagebrium, an advanced glycation endproduct breaker, on exercise tolerance and cardiac function in patients with chronic heart failure

(2011) Jasper W.L. Hartog et al.   EUROPEAN JOURNAL OF HEART FAILURE

Advanced oxidation protein products (AOPP): novel uremic toxins, or components of the non-enzymatic antioxidant system of the plasma proteome?

(2011) László Selmeci   FREE RADICAL RESEARCH

Biomarkers in chronic kidney disease: a review

(2011) Robert G. Fassett et al.   KIDNEY INTERNATIONAL

The association of receptor of advanced glycated end products and inflammatory mediators contributes to endothelial dysfunction in a prospective study of acute kidney injury patients with sepsis

(2011) Nermin A. H. Sadik et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Large shifts in pKa values of lysine residues buried inside a protein

(2011) D. G. Isom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiphoton spectral microscopy for imaging and quantification of tissue glycation

(2011) Jo-Ya Tseng et al.   Biomedical Optics Express

Plasma nitroproteome of kidney disease patients

(2010) Marta Piroddi et al.   AMINO ACIDS

Identification and relative quantification of specific glycation sites in human serum albumin

(2010) Andrej Frolov et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

HDL in humans with cardiovascular disease exhibits a proteomic signature

(2010) Tomáš Vaisar et al.   CLINICA CHIMICA ACTA

Advanced glycation end-products and the kidney

(2010) Martin Busch et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Protein damage in diabetes and uremia—identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect

(2010) Paul J. Thornalley et al.   FREE RADICAL RESEARCH

Exchange of Apolipoprotein A-I between Lipid-associated and Lipid-free States

(2010) Giorgio Cavigiolio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic Uremia Stimulates LDL Carbamylation and Atherosclerosis

(2010) E. O. Apostolov et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

N-Acetylcysteine for the Management of Anemia and Oxidative Stress in Hemodialysis Patients

(2010) Shih-Ping Hsu et al.   NEPHRON CLINICAL PRACTICE

Scavenger Receptors of Endothelial Cells Mediate the Uptake and Cellular Proatherogenic Effects of Carbamylated LDL

(2009) Eugene O. Apostolov et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hydrogen sulfide is a reversible inhibitor of the NADH oxidase activity of synaptic plasma membranes

(2009) Alejandro K. Samhan-Arias et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Albumin thiol oxidation and serum protein carbonyl formation are progressively enhanced with advancing stages of chronic kidney disease

(2009) Yukie Matsuyama et al.   Clinical and Experimental Nephrology

Protein carbonylation in kidney medulla of the spontaneously hypertensive rat

(2009) Raymond Tyther et al.   Proteomics Clinical Applications

Accumulation of Advanced Glycation End Products and Chronic Complications in ESRD Treated by Dialysis

(2008) Robbert Meerwaldt et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Increased Glycation of Hemoglobin in Chronic Renal Failure Patients and Its Potential Role of Oxidative Stress

(2008) Nambiar Selvaraj et al.   ARCHIVES OF MEDICAL RESEARCH

Significant correlation of glycated albumin, but not glycated haemoglobin, with arterial stiffening in haemodialysis patients with type 2 diabetes

(2008) Yasuro Kumeda et al.   CLINICAL ENDOCRINOLOGY

Peroxynitrite inactivates human-tissue inhibitor of metalloproteinase-4

(2008) Sandra Donnini et al.   FEBS LETTERS

Oxidative Stress and Covalent Modification of Protein with Bioactive Aldehydes

(2008) Paul A. Grimsrud et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Perspective on the Maillard Reaction and the Analysis of Protein Glycation by Mass Spectrometry: Probing the Pathogenesis of Chronic Disease

(2008) Qibin Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Association of glycated albumin, but not glycated hemoglobin, with peripheral vascular calcification in hemodialysis patients with type 2 diabetes

(2008) Shinsuke Yamada et al.   LIFE SCIENCES