Emerging role of microRNAs in regulating macrophage activation and polarization in immune response and inflammation

Telomerase reverse transcriptase acts in a feedback loop with NF-κB pathway to regulate macrophage polarization in alcoholic liver disease

(2016) Xiao-qin Wu et al.   Scientific Reports

MicroRNA-16 modulates macrophage polarization leading to improved insulin sensitivity in myoblasts

(2015) Malathi Talari et al.   BIOCHIMIE

Colony stimulating factor-1 receptor signaling networks inhibit mouse macrophage inflammatory responses by induction of microRNA-21

(2015) C. I. Caescu et al.   BLOOD

MicroRNA let-7 Modulates the Immune Response to Mycobacterium tuberculosis Infection via Control of A20, an Inhibitor of the NF-κB Pathway

(2015) Manish Kumar et al.   Cell Host & Microbe

MicroRNA-101 overexpression by IL-6 and TNF-α inhibits cholesterol efflux by suppressing ATP-binding cassette transporter A1 expression

(2015) Nan Zhang et al.   EXPERIMENTAL CELL RESEARCH

Liver inflammation abrogates immunological tolerance induced by Kupffer cells

(2015) Felix Heymann et al.   HEPATOLOGY

MicroRNA Cargo of Extracellular Vesicles from Alcohol-exposed Monocytes Signals Naive Monocytes to Differentiate into M2 Macrophages

(2015) Banishree Saha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

(2015) Mireille Ouimet et al.   JOURNAL OF CLINICAL INVESTIGATION

Alcohol-Induced miR-27a Regulates Differentiation and M2 Macrophage Polarization of Normal Human Monocytes

(2015) Banishree Saha et al.   JOURNAL OF IMMUNOLOGY

Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies

(2015) C Raggi et al.   ONCOGENE

Macrophage development and polarization in chronic inflammation

(2015) Madhur P. Motwani et al.   SEMINARS IN IMMUNOLOGY

Macrophages and cancer: from mechanisms to therapeutic implications

(2015) Renato Ostuni et al.   TRENDS IN IMMUNOLOGY

Functions of miR-146a and miR-222 in Tumor-associated Macrophages in Breast Cancer

(2015) Yanshuang Li et al.   Scientific Reports

MicroRNA 21 Is a Homeostatic Regulator of Macrophage Polarization and Prevents Prostaglandin E2-Mediated M2 Generation

(2015) Zhuo Wang et al.   PLoS One

MicroRNA let-7a: a novel therapeutic candidate in prostate cancer

(2014) Jun Li et al.   ASIAN JOURNAL OF ANDROLOGY

Polycomb-mediated loss of microRNA let-7c determines inflammatory macrophage polarization via PAK1-dependent NF-κB pathway

(2014) W Zhang et al.   CELL DEATH AND DIFFERENTIATION

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

MicroRNA profiling reveals opposing expression patterns for miR-511 in alternatively and classically activated macrophages

(2014) Danielle Karo-Atar et al.   JOURNAL OF ASTHMA

Genkwanin Inhibits Proinflammatory Mediators Mainly through the Regulation of miR-101/MKP-1/MAPK Pathway in LPS-Activated Macrophages

(2014) Yuan Gao et al.   PLoS One

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

miR-155 as a multiple sclerosis-relevant regulator of myeloid cell polarization

(2013) Craig S. Moore et al.   ANNALS OF NEUROLOGY

Transcriptional Control of Macrophage Polarization

(2013) Derin Tugal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNAs in Immune Response and Macrophage Polarization

(2013) Gang Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration

(2013) Abdoulaye Sene et al.   Cell Metabolism

Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways

(2013) Dexi Zhou et al.   CELLULAR SIGNALLING

The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1- and microRNA-155 –Dependent Pathway During Atherosclerosis

(2013) Yuanyuan Wei et al.   CIRCULATION

miR-125a-5p Regulates Differential Activation of Macrophages and Inflammation

(2013) Sami Banerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA let-7c Regulates Macrophage Polarization

(2013) S. Banerjee et al.   JOURNAL OF IMMUNOLOGY

Akt2 Deficiency Protects from Acute Lung Injury via Alternative Macrophage Activation and miR-146a Induction in Mice

(2013) E. Vergadi et al.   JOURNAL OF IMMUNOLOGY

Prostaglandin E2-Induced Changes in Alveolar Macrophage Scavenger Receptor Profiles Differentially Alter Phagocytosis of Pseudomonas aeruginosa and Staphylococcus aureus Post-Bone Marrow Transplant

(2013) R. Domingo-Gonzalez et al.   JOURNAL OF IMMUNOLOGY

Akt1-Mediated Regulation of Macrophage Polarization in a Murine Model of Staphylococcus aureus Pulmonary Infection

(2013) Feng Xu et al.   JOURNAL OF INFECTIOUS DISEASES

MyD88 as a target of microRNA-203 in regulation of lipopolysaccharide or Bacille Calmette-Guerin induced inflammatory response of macrophage RAW264.7 cells

(2013) Jun Wei et al.   MOLECULAR IMMUNOLOGY

In vivo genome-wide profiling of RNA secondary structure reveals novel regulatory features

(2013) Yiliang Ding et al.   NATURE

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

IL-4/IL-13-Dependent and Independent Expression of miR-124 and Its Contribution to M2 Phenotype of Monocytic Cells in Normal Conditions and during Allergic Inflammation

(2013) Tatyana Veremeyko et al.   PLoS One

Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b

(2013) G. Curtale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of IL-4R -dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo

(2012) D. Ruckerl et al.   BLOOD

A Novel Regulator of Macrophage Activation

(2012) Guoqing Zhuang et al.   CIRCULATION

MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS

(2012) Eugene D. Ponomarev et al.   GLIA

Identifying Functional MicroRNAs in Macrophages with Polarized Phenotypes

(2012) Joel W. Graff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages

(2012) Maliheh Nazari-Jahantigh et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

miRNA-125b regulates TNF-α production in CD14+ neonatal monocytes via post-transcriptional regulation

(2012) Hsin-Chun Huang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization

(2012) A. Arranz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs miR-125a and miR-125b constitutively activate the NF- B pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)

(2012) S.-W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-10-induced microRNA-187 negatively regulates TNF- , IL-6, and IL-12p40 production in TLR4-stimulated monocytes

(2012) M. Rossato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-511-3p Modulates Genetic Programs of Tumor-Associated Macrophages

(2012) Mario Leonardo Squadrito et al.   Cell Reports

MicroRNAs and the resolution phase of inflammation in macrophages

(2011) Muhammad M. Alam et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MicroRNA-98 negatively regulates IL-10 production and endotoxin tolerance in macrophages after LPS stimulation

(2011) Yang Liu et al.   FEBS LETTERS

MicroRNA-125b Potentiates Macrophage Activation

(2011) Aadel A. Chaudhuri et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b

(2011) M. V. S. Rajaram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-378 ∗ Mediates Metabolic Shift in Breast Cancer Cells via the PGC-1β/ERRγ Transcriptional Pathway

(2010) Lillian J. Eichner et al.   Cell Metabolism

MicroRNA-155 Regulates Inflammatory Cytokine Production in Tumor-associated Macrophages via Targeting C/EBPβ

(2010) Min He et al.   Cellular & Molecular Immunology

Identification of MyD88 as a novel target of miR-155, involved in negative regulation ofHelicobacter pylori-induced inflammation

(2010) Bin Tang et al.   FEBS LETTERS

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

The Interleukin 13 (IL-13) Pathway in Human Macrophages Is Modulated by MicroRNA-155 via Direct Targeting of Interleukin 13 Receptor α1 (IL13Rα1)

(2010) Rocio T. Martinez-Nunez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice

(2010) Partha S. Biswas et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-101 Targets MAPK Phosphatase-1 To Regulate the Activation of MAPKs in Macrophages

(2010) Q.-Y. Zhu et al.   JOURNAL OF IMMUNOLOGY

Estradiol Suppresses NF- B Activation through Coordinated Regulation of let-7a and miR-125b in Primary Human Macrophages

(2010) A. J. Murphy et al.   JOURNAL OF IMMUNOLOGY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

(2010) Eugene D Ponomarev et al.   NATURE MEDICINE

Desperately seeking microRNA targets

(2010) Marshall Thomas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

miR-155 gene: A typical multifunctional microRNA

(2009) Isabella Faraoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs

(2009) Ariadne Androulidaki et al.   IMMUNITY

MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2

(2009) J. Hou et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression

(2009) T. X. Lu et al.   JOURNAL OF IMMUNOLOGY

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses

(2009) G. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inositol phosphatase SHIP1 is a primary target of miR-155

(2009) R. M. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals

(2009) F. Bazzoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs: Novel Regulators During the Immune Response

(2008) Yujing Bi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNAs: new regulators of immune cell development and function

(2008) David Baltimore et al.   NATURE IMMUNOLOGY

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark