Melatonin pretreatment alleviates the long‐term synaptic toxicity and dysmyelination induced by neonatal Sevoflurane exposure via MT1 receptor‐mediated Wnt signaling modulation

Sevoflurane anesthesia during pregnancy in mice induces cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis

(2020) Yong Zuo et al.   NEUROCHEMISTRY INTERNATIONAL

Correction to: EPAC Negatively Regulates Myelination via Controlling Proliferation of Oligodendrocyte Precursor Cells

(2020) Zheng-Zheng Gao et al.   Neuroscience Bulletin

Enhancing WNT Signaling Restores Cortical Neuronal Spine Maturation and Synaptogenesis in Tbr1 Mutants

(2020) Siavash Fazel Darbandi et al.   Cell Reports

Sevoflurane Post-Conditioning Ameliorates Neuronal Deficits and Axon Demyelination After Neonatal Hypoxic Ischemic Brain Injury: Role of Microglia/Macrophage

(2020) Hang Xue et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Effects of melatonin on acute brain reperfusion stress: role of Hippo signaling pathway and MFN2-related mitochondrial protection

(2019) Song Lan et al.   CELL STRESS & CHAPERONES

Disrupted folate metabolism with anesthesia leads to myelination deficits mediated by epigenetic regulation of ERMN

(2019) Lei Zhang et al.   EBioMedicine

Effects of the application of general anesthesia with propofol during the early stage of pregnancy on brain development and function of SD rat offspring and the intervention of DHA

(2019) Xiangming Yu et al.   NEUROLOGICAL RESEARCH

Cognitive impairment and transcriptomic profile in hippocampus of young mice after multiple neonatal exposures to sevoflurane

(2019) Shao-Yong Song et al.   Aging-US

Knockdown of long noncoding RNA WNT5A-AS restores the fate of neural stem cells exposed to sevoflurane via inhibiting WNT5A/Ryk-ROS signaling

(2019) Guolin Lu et al.   BIOMEDICINE & PHARMACOTHERAPY

Involvement of HIPK2‐JNK/c‐Jun cascade in the long term synaptic toxicity and cognition impairment induced by neonatal Sevoflurane exposure

(2019) Lirong Liang et al.   JOURNAL OF NEUROCHEMISTRY

Sevoflurane-induced inflammation development

(2019) Jian Yin et al.   BEHAVIOURAL PHARMACOLOGY

Sevoflurane induces apoptosis and inhibits the growth and motility of colon cancer in vitro and in vivo via inactivating Ras/Raf/MEK/ERK signaling

(2019) Xiao Yang et al.   LIFE SCIENCES

Food and Drug Administration warning on anesthesia and brain development: implications for obstetric and fetal surgery

(2018) Olutoyin A. Olutoye et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation

(2018) Nava Zisapel   BRITISH JOURNAL OF PHARMACOLOGY

Elevated expression of DJ-1 (encoded by the human PARK7 gene) protects neuronal cells from sevoflurane-induced neurotoxicity

(2018) Yajie Zhang et al.   CELL STRESS & CHAPERONES

Melatonin attenuated retinal neovascularization and neuroglial dysfunction by inhibition of HIF-1α-VEGF pathway in oxygen-induced retinopathy mice

(2018) Yue Xu et al.   JOURNAL OF PINEAL RESEARCH

Neuroprotective effect of melatonin against lipopolysaccharide-induced depressive-like behavior in mice

(2018) E.H. Taniguti et al.   PHYSIOLOGY & BEHAVIOR

Volatile anesthetics sevoflurane targets leukemia stem/progenitor cells via Wnt/β-catenin inhibition

(2018) Xuguang Ruan et al.   BIOMEDICINE & PHARMACOTHERAPY

SIRT3 activator honokiol ameliorates surgery/anesthesia-induced cognitive decline in mice through anti-oxidative stress and anti-inflammatory in hippocampus

(2018) Ji-Shi Ye et al.   CNS Neuroscience & Therapeutics

Early life exposure to extended general anesthesia with isoflurane and nitrous oxide reduces responsivity on a cognitive test battery in the nonhuman primate

(2018) John C. Talpos et al.   NEUROTOXICOLOGY

Administration of Momordica charantia Enhances the Neuroprotection and Reduces the Side Effects of LiCl in the Treatment of Alzheimer’s Disease

(2018) Hei-Jen Huang et al.   Nutrients

Sevoflurane-induced learning deficits and spine loss via nectin-1/corticotrophin-releasing hormone receptor type 1 signaling

(2018) Yize Li et al.   BRAIN RESEARCH

Melatonin enhances survival and preserves functional integrity of stem cells: A review

(2017) Mel S. Lee et al.   JOURNAL OF PINEAL RESEARCH

Multiple sevoflurane anesthesia in pregnant mice inhibits neurogenesis of fetal hippocampus via repressing transcription factor Pax6

(2017) Fang Fang et al.   LIFE SCIENCES

Sevoflurane Affects Oxidative Stress and Alters Apoptosis Status in Children and Cultured Neural Stem Cells

(2017) Xue Zhou et al.   NEUROTOXICITY RESEARCH

Melatonin Augments the Effects of Fluoxetine on Depression-Like Behavior and Hippocampal BDNF–TrkB Signaling

(2017) Kun Li et al.   Neuroscience Bulletin

Melatonin in Pregnancy: Effects on Brain Development and CNS Programming Disorders

(2016) Lucas Sagrillo-Fagundes et al.   CURRENT PHARMACEUTICAL DESIGN

The role of the Wnt/β-catenin-Annexin A1 pathway in the process of sevoflurane-induced cognitive dysfunction

(2016) Nan Hu et al.   JOURNAL OF NEUROCHEMISTRY

Efficacy of N-Acetylserotonin and Melatonin in the EAE Model of Multiple Sclerosis

(2016) Jie Wen et al.   Journal of Neuroimmune Pharmacology

Melatoninergic System in Parkinson’s Disease: From Neuroprotection to the Management of Motor and Nonmotor Symptoms

(2016) Josiel Mileno Mack et al.   Oxidative Medicine and Cellular Longevity

Neurobehavioural abnormalities induced by repeated exposure of neonatal rats to sevoflurane can be aggravated by social isolation and enrichment deprivation initiated after exposure to the anaesthetic

(2015) M.Q. Zhang et al.   BRITISH JOURNAL OF ANAESTHESIA

Neurodevelopmental implications of the general anesthesia in neonate and infants

(2015) Jin Hwan Lee et al.   EXPERIMENTAL NEUROLOGY

Analgesic, Anxiolytic and Anaesthetic Effects of Melatonin: New Potential Uses in Pediatrics

(2015) Lucia Marseglia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism

(2015) Dun-Xian Tan et al.   MOLECULES

Oligodendrocytes: Myelination and Axonal Support

(2015) Mikael Simons et al.   Cold Spring Harbor Perspectives in Biology

Treatment with melatonin after status epilepticus attenuates seizure activity and neuronal damage but does not prevent the disturbance in diurnal rhythms and behavioral alterations in spontaneously hypertensive rats in kainate model of temporal lobe epilepsy

(2014) Zlatina Petkova et al.   EPILEPSY & BEHAVIOR

Melatonin attenuates dexamethasone-induced spatial memory impairment and dexamethasone-induced reduction of synaptic protein expressions in the mouse brain

(2013) Walaiporn Tongjaroenbuangam et al.   NEUROCHEMISTRY INTERNATIONAL

Impaired Spatial Learning and Memory after Sevoflurane–Nitrous Oxide Anesthesia in Aged Rats Is Associated with Down-Regulated cAMP/CREB Signaling

(2013) Wan-Xia Xiong et al.   PLoS One

WNT signaling in neuronal maturation and synaptogenesis

(2013) Silvana B. Rosso et al.   Frontiers in Cellular Neuroscience

Galectin-3 drives oligodendrocyte differentiation to control myelin integrity and function

(2011) L A Pasquini et al.   CELL DEATH AND DIFFERENTIATION

Wnt signaling during synaptic development and plasticity

(2011) Vivian Budnik et al.   CURRENT OPINION IN NEUROBIOLOGY

Canonical Wnt signaling promotes the proliferation and neurogenesis of peripheral olfactory stem cells during postnatal development and adult regeneration

(2011) Y.-Z. Wang et al.   JOURNAL OF CELL SCIENCE

Regulation of Oligodendrocyte Differentiation and Myelination

(2010) B. Emery   SCIENCE

Rapid, reproducible transduction of select forebrain regions by targeted recombinant virus injection into the neonatal mouse brain

(2009) Noam Pilpel et al.   JOURNAL OF NEUROSCIENCE METHODS

Physiological effects of melatonin: Role of melatonin receptors and signal transduction pathways

(2008) S PANDIPERUMAL et al.   PROGRESS IN NEUROBIOLOGY