Administration of Momordica charantia Enhances the Neuroprotection and Reduces the Side Effects of LiCl in the Treatment of Alzheimer’s Disease

MGCD0103, a selective histone deacetylase inhibitor, coameliorates oligomeric Aβ25-35 -induced anxiety and cognitive deficits in a mouse model

(2018) Hei-Jen Huang et al.   CNS Neuroscience & Therapeutics

A review on flavonoid-based scaffolds as multi-target-directed ligands (MTDLs) for Alzheimer's disease

(2018) Leili Jalili-Baleh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel multi-target directed ligand-based strategies for reducing neuroinflammation in Alzheimer's disease

(2018) Tyler Joseph Wenzel et al.   LIFE SCIENCES

Effect of tomato variety, cultivation, climate and processing on Sola l 4, an allergen from Solanum lycopersicum

(2018) Elisabeth Kurze et al.   PLoS One

Phytochemical and genetic characterization of styles of wild Crocus species from the island of Crete, Greece and comparison to those of cultivated C. sativus

(2018) Fotini N. Lamari et al.   FITOTERAPIA

Streptozotocin-Induced Sporadic Alzheimer's Disease: Selection of Appropriate Dose

(2018) Jogender Mehla et al.   JOURNAL OF ALZHEIMERS DISEASE

Impact of substrate contamination with mycotoxins, heavy metals and pesticides on growth performance and composition of black soldier fly larvae (Hermetia illucens) for use in the feed and food value chain

(2017) Benedict Purschke et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Momordica charantia: a popular health-promoting vegetable with multifunctionality

(2017) Shuzhen Wang et al.   Food & Function

Berberine Ameliorates Diabetes-Associated Cognitive Decline through Modulation of Aberrant Inflammation Response and Insulin Signaling Pathway in DM Rats

(2017) Qingjie Chen et al.   Frontiers in Pharmacology

Modeling Sporadic Alzheimer's Disease: The Insulin Resistant Brain State Generates Multiple Long-Term Morphobiological Abnormalities Including Hyperphosphorylated Tau Protein and Amyloid-β

(2017) Melita Salkovic-Petrisic et al.   JOURNAL OF ALZHEIMERS DISEASE

Identification of lead small molecule inhibitors of glycogen synthase kinase-3 beta using a fragment-linking strategy

(2016) Jinhee Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Alzheimer's Disease Risk and Progression: The Role of Nutritional Supplements and their Effect on Drug Therapy Outcome

(2016) A. Giulietti et al.   Current Neuropharmacology

Antidiabetic activities of a cucurbitane-type triterpenoid compound from Momordica charantia in alloxan-induced diabetic mice

(2016) Bowen Jiang et al.   Molecular Medicine Reports

Intracerebroventricular Streptozotocin as a Model of Alzheimer’s Disease: Neurochemical and Behavioral Characterization in Mice

(2016) Katherine Garcia Ravelli et al.   NEUROTOXICITY RESEARCH

PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer’s disease model

(2016) Loukia Katsouri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer’s disease model

(2016) Jiqing Xu et al.   Scientific Reports

GM1-Modified Lipoprotein-like Nanoparticle: Multifunctional Nanoplatform for the Combination Therapy of Alzheimer’s Disease

(2015) Meng Huang et al.   ACS Nano

Supplementation of fresh ucche (Momordica charantia L. var. muricata Willd) prevented oxidative stress, fibrosis and hepatic damage in CCl4 treated rats

(2015) Abu Taher Sagor et al.   BMC Complementary and Alternative Medicine

The combination of lithium and l-Dopa/Carbidopa reduces MPTP-induced abnormal involuntary movements (AIMs) via calpain-1 inhibition in a mouse model: Relevance for Parkinson׳s disease therapy

(2015) Carol A. Lazzara et al.   BRAIN RESEARCH

Quantitative Expression Analysis of APP Pathway and Tau Phosphorylation-Related Genes in the ICV STZ-Induced Non-Human Primate Model of Sporadic Alzheimer’s Disease

(2015) Sang-Je Park et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease

(2015) Sagar H. Barage et al.   NEUROPEPTIDES

Challenging conventional risk assessment with respect to human exposure to multiple food contaminants in food: A case study using maize.

(2015) R. Clarke et al.   TOXICOLOGY LETTERS

Administration of NaHS Attenuates Footshock-Induced Pathologies and Emotional and Cognitive Dysfunction in Triple Transgenic Alzheimer’s Mice

(2015) Hei-Jen Huang et al.   Frontiers in Behavioral Neuroscience

Computational identification of potential multi-drug combinations for reduction of microglial inflammation in Alzheimer disease

(2015) Thomas J. Anastasio   Frontiers in Pharmacology

Anti-Inflammatory Effect of Momordica Charantia in Sepsis Mice

(2014) Che-Yi Chao et al.   MOLECULES

Wild bitter gourd protects against alcoholic fatty liver in mice by attenuating oxidative stress and inflammatory responses

(2014) Kuan-Hung Lu et al.   Food & Function

An in vitro study on the risk of non-allergic type-I like hypersensitivity to Momordica charantia

(2013) Rahsan Ilikci Sagkan   BMC Complementary and Alternative Medicine

Diabetes Mellitus and Inflammation

(2013) Eric Lontchi-Yimagou et al.   Current Diabetes Reports

Role of GLP-1 in the Hypoglycemic Effects of Wild Bitter Gourd

(2013) Ting-ni Huang et al.   Evidence-based Complementary and Alternative Medicine

How Do Immune Cells Support and Shape the Brain in Health, Disease, and Aging?

(2013) M. Schwartz et al.   JOURNAL OF NEUROSCIENCE

Intracerebroventricular Streptozotocin Exacerbates Alzheimer-Like Changes of 3xTg-AD Mice

(2013) Yanxing Chen et al.   MOLECULAR NEUROBIOLOGY

Glial activation and post-synaptic neurotoxicity: The key events in Streptozotocin (ICV) induced memory impairment in rats

(2013) Shivika Rai et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Tau protein kinases: Involvement in Alzheimer's disease

(2012) Ludovic Martin et al.   AGEING RESEARCH REVIEWS

Lithium exacerbates hepatic ischemia/reperfusion injury by inhibiting GSK-3β/NF-κB-mediated protective signaling in mice

(2012) Yongxiang Xia et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

(2012) Cristian A. Lasagna-Reeves et al.   FASEB JOURNAL

Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes

(2012) Philip T.T. Ly et al.   JOURNAL OF CLINICAL INVESTIGATION

Lithium Reduces BACE1 Overexpression, Beta Amyloid Accumulation, and Spatial Learning Deficits in Mice with Traumatic Brain Injury

(2012) Fengshan Yu et al.   JOURNAL OF NEUROTRAUMA

Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model

(2012) Siva Sundara Kumar Durairajan et al.   NEUROBIOLOGY OF AGING

Wild bitter gourd improves metabolic syndrome: A preliminary dietary supplementation trial

(2012) Chung-Huang Tsai et al.   Nutrition Journal

Tau as a therapeutic target in neurodegenerative disease

(2012) Diana S. Himmelstein et al.   PHARMACOLOGY & THERAPEUTICS

Exendin-4 Protected against Cognitive Dysfunction in Hyperglycemic Mice Receiving an Intrahippocampal Lipopolysaccharide Injection

(2012) Hei-Jen Huang et al.   PLoS One

Brain Gene Expression of a Sporadic (icv-STZ Mouse) and a Familial Mouse Model (3xTg-AD Mouse) of Alzheimer’s Disease

(2012) Yanxing Chen et al.   PLoS One

Disease-modifying properties of long-term lithium treatment for amnestic mild cognitive impairment: randomised controlled trial

(2011) Orestes V. Forlenza et al.   BRITISH JOURNAL OF PSYCHIATRY

Characterization of Prefibrillar Tau Oligomersin Vitroand in Alzheimer Disease

(2011) Kristina R. Patterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammation

(2011) Pratibha V Nerurkar et al.   Journal of Neuroinflammation

Does lithium protect against dementia?

(2010) Lars Vedel Kessing et al.   BIPOLAR DISORDERS

NFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapy

(2010) Raquel Gómez-Sintes et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuroprotective effect of Momordica charantia in global cerebral ischemia and reperfusion induced neuronal damage in diabetic mice

(2010) Zafar Ahmad Malik et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuroimmunomodulation in the Pathogenesis of Alzheimer’s Disease

(2010) Inelia Morales et al.   NEUROIMMUNOMODULATION

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microtubule proteins and their post-translational forms in the cerebrospinal fluid of patients with paraparesis associated with HTLV-I infection and in SH-SY5Y cells: An in vitro model of HTLV-I-induced disease

(2009) HORACIO MALDONADO et al.   BIOLOGICAL RESEARCH

Can Lithium or Valproate Untie Tangles in Alzheimer's Disease?

(2009) Pierre N. Tariot et al.   JOURNAL OF CLINICAL PSYCHIATRY

Lithium Treatment Decreases Activities of Tau Kinases in a Murine Model of Senescence

(2009) Marta Tajes et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Lithium Treatment and Risk of Dementia

(2008) Lars Vedel Kessing et al.   ARCHIVES OF GENERAL PSYCHIATRY

Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model

(2008) H.-L. Feng et al.   NEUROSCIENCE