The role of protein tyrosine phosphatase 1B (PTP1B) in the pathogenesis of type 2 diabetes mellitus and its complications
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Title
The role of protein tyrosine phosphatase 1B (PTP1B) in the pathogenesis of type 2 diabetes mellitus and its complications
Authors
Keywords
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Journal
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-01-06
DOI
10.1007/s13105-021-00860-7
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Note: Only part of the references are listed.- Association of Protein Tyrosine Phosphatase 1B ( PTPN1 ) Gene Polymorphism with the Effects of Weight Reduction Therapy on Body Weight and Glycolipid Profiles in Obese Patients
- (2021) Hajime Yamakage et al. Journal of Diabetes Investigation
- The protective role of MiR-206 in regulating cardiomyocytes apoptosis induced by ischemic injury by targeting PTP1B
- (2020) Yejun Yan et al. BIOSCIENCE REPORTS
- Selective deficiency in endothelial PTP1B protects from diabetes and endoplasmic reticulum stress-associated endothelial dysfunction via preventing endothelial cell apoptosis
- (2020) Samuel Legeay et al. BIOMEDICINE & PHARMACOTHERAPY
- Recent advance on PTP1B inhibitors and their biomedical applications
- (2020) Bigyan Sharma et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Protein tyrosine phosphatase 1B inhibition as a potential therapeutic target for chronic wounds in diabetes
- (2020) Ana Figueiredo et al. PHARMACOLOGICAL RESEARCH
- The mode of action of the Protein tyrosine phosphatase 1B inhibitor Ertiprotafib
- (2020) Ganesan Senthil Kumar et al. PLoS One
- Up-regulating microRNA-203 alleviates myocardial remodeling and cell apoptosis through down-regulating PTP1B in rats with myocardial infarction
- (2019) Jing Zhang et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Role of PTP1B in POMC neurons during chronic high-fat diet: sex differences in regulation of liver lipids and glucose tolerance
- (2018) Nicola Aberdein et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- miR-338-3p functions as a tumor suppressor in gastric cancer by targeting PTP1B
- (2018) Feng Sun et al. Cell Death & Disease
- A novel PTP1B inhibitor extracted from Ganoderma lucidum ameliorates insulin resistance by regulating IRS1-GLUT4 cascades in the insulin signaling pathway
- (2018) Zhou Yang et al. Food & Function
- Enhanced insulin receptor, but not PI3K, signalling protects podocytes from ER stress
- (2018) Kathryn L. Garner et al. Scientific Reports
- Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis
- (2018) Águeda González-Rodríguez et al. Molecular Metabolism
- Novel benzamido derivatives as PTP1B inhibitors with anti-hyperglycemic and lipid-lowering efficacy
- (2018) Yanbo Tang et al. Acta Pharmaceutica Sinica B
- PTP 1B markedly promotes breast cancer progression and is regulated by miR‐193a‐3p
- (2018) Mengchao Yu et al. FEBS Journal
- The Evolving Importance of Insulin Signaling in Podocyte Health and Disease
- (2018) Abigail C. Lay et al. Frontiers in Endocrinology
- Folic Acid Supplementation Delays Atherosclerotic Lesion Development by Modulating MCP1 and VEGF DNA Methylation Levels In Vivo and In Vitro
- (2017) Shanshan Cui et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A potent, selective, and orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models
- (2017) Navasona Krishnan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein tyrosine phosphatase 1B deficiency in podocytes mitigates hyperglycemia-induced renal injury
- (2017) Yoshihiro Ito et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Knocking down amygdalar PTP1B in diet-induced obese rats improves insulin signaling/action, decreases adiposity and may alter anxiety behavior
- (2017) Natalia Ferreira Mendes et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE −/− mouse model of atherosclerosis with alterations in IL10/AMPKα pathway
- (2017) D. Thompson et al. Molecular Metabolism
- Endothelial deletion of protein tyrosine phosphatase-1B protects against pressure overload-induced heart failure in mice
- (2016) Rajinikanth Gogiraju et al. CARDIOVASCULAR RESEARCH
- Selective Vascular Endothelial Protection Reduces Cardiac Dysfunction in Chronic Heart FailureCLINICAL PERSPECTIVE
- (2016) Julie Maupoint et al. Circulation-Heart Failure
- S -nitrosylation of endogenous protein tyrosine phosphatases in endothelial insulin signaling
- (2016) Ming-Fo Hsu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Functional properties of Claramine: A novel PTP1B inhibitor and insulin-mimetic compound
- (2015) Zhaohong Qin et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Recent advances in understanding the biochemical and molecular mechanism of diabetic retinopathy
- (2015) Ting-Ting Wan et al. BIOMEDICINE & PHARMACOTHERAPY
- SH2 domain-containing inositol 5-phosphatase (SHIP2) inhibition ameliorates high glucose-induced de-novo lipogenesis and VLDL production through regulating AMPK/mTOR/SREBP1 pathway and ROS production in HepG2 cells
- (2015) Sattar Gorgani-Firuzjaee et al. FREE RADICAL BIOLOGY AND MEDICINE
- The Role of PTP1B O-GlcNAcylation in Hepatic Insulin Resistance
- (2015) Yun Zhao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- UBC9-dependent Association between Calnexin and Protein Tyrosine Phosphatase 1B (PTP1B) at the Endoplasmic Reticulum
- (2015) Dukgyu Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Curcumin protects against fructose-induced podocyte insulin signaling impairment through upregulation of miR-206
- (2015) Xiao-Qin Ding et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Deletion of protein tyrosine phosphatase 1b in proopiomelanocortin neurons reduces neurogenic control of blood pressure and protects mice from leptin- and sympatho-mediated hypertension
- (2015) Thiago Bruder-Nascimento et al. PHARMACOLOGICAL RESEARCH
- Pathophysiology of type 1 and type 2 diabetes mellitus: a 90-year perspective
- (2015) Francesco Zaccardi et al. POSTGRADUATE MEDICAL JOURNAL
- Protein-tyrosine phosphatase 1B substrates and metabolic regulation
- (2015) Jesse Bakke et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- miR-744 enhances type I interferon signaling pathway by targeting PTP1B in primary human renal mesangial cells
- (2015) Xiaoyan Zhang et al. Scientific Reports
- Deletion of Protein Tyrosine Phosphatase 1B (PTP1B) Enhances Endothelial Cyclooxygenase 2 Expression and Protects Mice from Type 1 Diabetes-Induced Endothelial Dysfunction
- (2015) David J. Herre et al. PLoS One
- Protein Tyrosine Phosphatase 1B Inhibition Protects against Podocyte Injury and Proteinuria
- (2014) Takanori Kumagai et al. AMERICAN JOURNAL OF PATHOLOGY
- Gene Deletion of Protein Tyrosine Phosphatase 1B Protects Against Sepsis-Induced Cardiovascular Dysfunction and Mortality
- (2014) David Coquerel et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Hepatic protein tyrosine phosphatase 1B (PTP1B) deficiency protects against obesity-induced endothelial dysfunction
- (2014) Abdelali Agouni et al. BIOCHEMICAL PHARMACOLOGY
- Disruption of Protein-Tyrosine Phosphatase 1B Expression in the Pancreas Affects β-Cell Function
- (2014) Siming Liu et al. ENDOCRINOLOGY
- PTP1B inhibitors for type 2 diabetes treatment: a patent review (2011 – 2014)
- (2014) Akhilesh Kumar Tamrakar et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Oligonucleotide delivery: a patent review (2010 – 2013)
- (2014) Santiago Grijalvo et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Enhanced angiogenesis and increased cardiac perfusion after myocardial infarction in protein tyrosine phosphatase 1B-deficient mice
- (2014) Marie Besnier et al. FASEB JOURNAL
- The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity
- (2014) David Medgyesi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Protein Tyrosine Phosphatase-1B Modulates Pancreatic β-cell Mass
- (2014) Rebeca Fernandez-Ruiz et al. PLoS One
- Improved metabolic phenotype of hypothalamic PTP1B-deficiency is dependent upon the leptin receptor
- (2014) Ryan C. Tsou et al. Molecular Metabolism
- Recent advances in understanding the biochemical and molecular mechanism of diabetic nephropathy
- (2013) Yan-Ming Sun et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Discovery of novel PTP1B inhibitors via pharmacophore-oriented scaffold hopping from Ertiprotafib
- (2013) Jun-Zheng Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Structural and functional characteristics of cGMP-dependent methionine oxidation in Arabidopsis thaliana proteins
- (2013) Claudius Marondedze et al. Cell Communication and Signaling
- PTP1B: A simple enzyme for a complex world
- (2013) Matthew Feldhammer et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Pharmacological Inhibition of Protein Tyrosine Phosphatase 1B: A Promising Strategy for the Treatment of Obesity and Type 2 Diabetes Mellitus
- (2013) E. Panzhinskiy et al. CURRENT MEDICINAL CHEMISTRY
- Podocyte-Specific GLUT4-Deficient Mice Have Fewer and Larger Podocytes and Are Protected From Diabetic Nephropathy
- (2013) J. Guzman et al. DIABETES
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- (2013) L. Grant et al. DIABETES
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- (2013) Gholamreza Taheripak et al. FREE RADICAL BIOLOGY AND MEDICINE
- MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer
- (2013) Lise Lotte Christensen et al. INTERNATIONAL JOURNAL OF CANCER
- Mechanisms of Diabetic Complications
- (2013) Josephine M. Forbes et al. PHYSIOLOGICAL REVIEWS
- Protein Tyrosine Phosphatase 1B and Insulin Resistance: Role of Endoplasmic Reticulum Stress/Reactive Oxygen Species/Nuclear Factor Kappa B Axis
- (2013) Evgeniy Panzhinskiy et al. PLoS One
- Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance
- (2013) Elaine Xu et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Molecular mechanisms in the pathogenesis of diabetic nephropathy: An update
- (2013) Mandeep Kumar Arora et al. VASCULAR PHARMACOLOGY
- Palmitate-induced PTP1B expression is mediated by ceramide-JNK and nuclear factor κB (NF-κB) activation
- (2012) Narges MohammadTaghvaei et al. CELLULAR SIGNALLING
- Skeletal Muscle Protein Tyrosine Phosphatase 1B Regulates Insulin Sensitivity in African Americans
- (2012) A. J. Stull et al. DIABETES
- Neuronal Androgen Receptor Regulates Insulin Sensitivity via Suppression of Hypothalamic NF- B-Mediated PTP1B Expression
- (2012) I.-C. Yu et al. DIABETES
- Mechanisms Involved in the Development and Healing of Diabetic Foot Ulceration
- (2012) T. Dinh et al. DIABETES
- Projections of Type 1 and Type 2 Diabetes Burden in the U.S. Population Aged
- (2012) G. Imperatore et al. DIABETES CARE
- Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals
- (2012) R. Robinson et al. Disease Models & Mechanisms
- PTP1B and TCPTP - nonredundant phosphatases in insulin signaling and glucose homeostasis
- (2012) Tony Tiganis FEBS Journal
- Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid
- (2012) Yoon Mee Yang et al. HEPATOLOGY
- Protein tyrosine phosphatase 1B (PTP1B) modulates palmitate-induced cytokine production in macrophage cells
- (2012) Ahmad Nasimian et al. INFLAMMATION RESEARCH
- Reduction of heart failure by pharmacological inhibition or gene deletion of protein tyrosine phosphatase 1B
- (2012) Elodie Gomez et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Adipocyte-Specific Protein Tyrosine Phosphatase 1B Deletion Increases Lipogenesis, Adipocyte Cell Size and Is a Minor Regulator of Glucose Homeostasis
- (2012) Carl Owen et al. PLoS One
- Protein Tyrosine Phosphatase 1B (PTP1B) Deficiency Accelerates Hepatic Regeneration in Mice
- (2011) Jesús Revuelta-Cervantes et al. AMERICAN JOURNAL OF PATHOLOGY
- Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control
- (2011) Doina Popov BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Fibroblasts and myofibroblasts in renal fibrosis
- (2011) Soma Meran et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Regulation byS-Nitrosylation of Protein Post-translational Modification
- (2011) Douglas T. Hess et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus
- (2011) Dwi Setyowati Karolina et al. PLoS One
- Palmitate and inflammatory state additively induce the expression of PTP1B in muscle cells
- (2010) Leila Parvaneh et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The regulation of leucocyte transendothelial migration by endothelial signalling events
- (2010) M. Fernandez-Borja et al. CARDIOVASCULAR RESEARCH
- Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009
- (2010) R. A. DeFronzo DIABETOLOGIA
- Palmitate Enhances Protein Tyrosine Phosphatase 1B (PTP1B) Gene Expression at Transcriptional Level in C2C12 Skeletal Muscle Cells
- (2010) Narges MohammadTaghvaei et al. INFLAMMATION
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- (2010) Raju V. S. Rajala et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effects of insulin and high glucose on mobilization of slo1 BKCa channels in podocytes
- (2010) Eun Young Kim et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Probing Interaction Requirements in PTP1B Inhibitors: A Comparative Molecular Dynamics Study
- (2010) Rajendra Kumar et al. Journal of Chemical Information and Modeling
- Diabetic retinopathy
- (2010) Ning Cheung et al. LANCET
- Protein Tyrosine Phosphatase 1B Inhibitors: A Molecular Level Legitimate Approach for the Management of Diabetes Mellitus
- (2010) Suresh Thareja et al. MEDICINAL RESEARCH REVIEWS
- Inhibition of PTP1B by Trodusquemine (MSI-1436) Causes Fat-specific Weight Loss in Diet-induced Obese Mice
- (2010) Kristen A. Lantz et al. Obesity
- PTP1B: a double agent in metabolism and oncogenesis
- (2010) Shu-Chin Yip et al. TRENDS IN BIOCHEMICAL SCIENCES
- In control at the ER: PTP1B and the down-regulation of RTKs by dephosphorylation and endocytosis
- (2010) Matthew Stuible et al. TRENDS IN CELL BIOLOGY
- Vascular actions of insulin with implications for endothelial dysfunction
- (2009) Maria Assunta Potenza et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- 5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors
- (2009) Rosaria Ottanà et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Deletion of Protein Tyrosine Phosphatase 1b Improves Peripheral Insulin Resistance and Vascular Function in Obese, Leptin-Resistant Mice via Reduced Oxidant Tone
- (2009) M. Irfan Ali et al. CIRCULATION RESEARCH
- Inhibition of PTP1B Restores IRS1-Mediated Hepatic Insulin Signaling in IRS2-Deficient Mice
- (2009) A. Gonzalez-Rodriguez et al. DIABETES
- Neuronal Protein Tyrosine Phosphatase 1B Deficiency Results in Inhibition of Hypothalamic AMPK and Isoform-Specific Activation of AMPK in Peripheral Tissues
- (2009) B. Xue et al. MOLECULAR AND CELLULAR BIOLOGY
- Emerging Concepts in the Pathophysiology of Type 2 Diabetes Mellitus
- (2009) Prasanth N. Surampudi et al. MOUNT SINAI JOURNAL OF MEDICINE
- Chronic insulin treatment suppresses PTP1B function, induces increased PDGF signaling, and amplifies neointima formation in the balloon-injured rat artery
- (2008) Qinghua Pu et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress
- (2008) M. Delibegovic et al. DIABETES
- Reduction of Hypothalamic Protein Tyrosine Phosphatase Improves Insulin and Leptin Resistance in Diet-Induced Obese Rats
- (2008) Paty Karoll Picardi et al. ENDOCRINOLOGY
- Protein-tyrosine Phosphatase 1B Expression Is Induced by Inflammationin Vivo
- (2008) Janice M. Zabolotny et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Loss of Neuroprotective Survival Signal in Mice Lacking Insulin Receptor Gene in Rod Photoreceptor Cells
- (2008) Ammaji Rajala et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion
- (2008) Christa L. Cortesio et al. JOURNAL OF CELL BIOLOGY
- Insulin resistance induced by tumor necrosis factor-α in myocytes and brown adipocytes12
- (2007) M. Lorenzo et al. JOURNAL OF ANIMAL SCIENCE
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