Curcumin protects against fructose-induced podocyte insulin signaling impairment through upregulation of miR-206

Curcumin Attenuates Urinary Excretion of Albumin in Type II Diabetic Patients with Enhancing Nuclear Factor Erythroid-Derived 2-Like 2 (Nrf2) System and Repressing Inflammatory Signaling Efficacies

(2015) H. Yang et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Pterostilbene and allopurinol reduce fructose-induced podocyte oxidative stress and inflammation via microRNA-377

(2015) Wei Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fumosorinone, a novel PTP1B inhibitor, activates insulin signaling in insulin-resistance HepG2 cells and shows anti-diabetic effect in diabetic KKAy mice

(2015) Zhi-Qin Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Protein Tyrosine Phosphatase 1B Inhibition Protects against Podocyte Injury and Proteinuria

(2014) Takanori Kumagai et al.   AMERICAN JOURNAL OF PATHOLOGY

Curcumin ameliorates epithelial-to-mesenchymal transition of podocytes in vivo and in vitro via regulating caveolin-1

(2014) Li-na Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Curcumin prevents diabetic nephropathy against inflammatory response via reversing caveolin-1 Tyr14 phosphorylation influenced TLR4 activation

(2014) Li-Na Sun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Endogenous Fructose Production and Fructokinase Activation Mediate Renal Injury in Diabetic Nephropathy

(2014) M. A. Lanaspa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Curcumin Ameliorates Podocytic Adhesive Capacity Damage Under Mechanical Stress By Inhibiting miR-124 Expression

(2014) Dong Li et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Betaine recovers hypothalamic neural injury by inhibiting astrogliosis and inflammation in fructose-fed rats

(2014) Jian-Mei Li et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Lipid-Lowering Effects of Curcumin in Patients with Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

(2014) Yi-Sun Yang et al.   PHYTOTHERAPY RESEARCH

Morin reduces hepatic inflammation-associated lipid accumulation in high fructose-fed rats via inhibiting sphingosine kinase 1/sphingosine 1-phosphate signaling pathway

(2013) Xing Wang et al.   BIOCHEMICAL PHARMACOLOGY

Curcumin alleviates immune-complex-mediated glomerulonephritis in factor-H-deficient mice

(2013) Alexander Jacob et al.   IMMUNOLOGY

Targeted delivery of curcumin for treating type 2 diabetes

(2013) Muralidhara Rao Maradana et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Chronic leucine supplementation increases body weight and insulin sensitivity in rats on high-fat diet likely by promoting insulin signaling in insulin-target tissues

(2013) Xiang Li et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Allopurinol, quercetin and rutin ameliorate renal NLRP3 inflammasome activation and lipid accumulation in fructose-fed rats

(2012) Qing-Hua Hu et al.   BIOCHEMICAL PHARMACOLOGY

Why it is necessary to translate curcumin into clinical practice for the prevention and treatment of metabolic syndrome?

(2012) Amirhossein Sahebkar   BIOFACTORS

Curcumin attenuates lupus nephritis upon interaction with regulatory T cells in New Zealand Black/White mice

(2012) Hyojung Lee et al.   BRITISH JOURNAL OF NUTRITION

Protective effects of peroxisome proliferator-activated receptor agonists on human podocytes: proposed mechanisms of action

(2012) Gianluca Miglio et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protection of curcumin against fructose-induced hyperuricaemia and renal endothelial dysfunction involves NO-mediated JAK–STAT signalling in rats

(2012) Dong-Mei Zhang et al.   FOOD CHEMISTRY

Genistein modulates NF-κB-associated renal inflammation, fibrosis and podocyte abnormalities in fructose-fed rats

(2011) Nallasamy Palanisamy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy

(2011) Olga Zhdanova et al.   KIDNEY INTERNATIONAL

Curcumin ameliorates macrophage infiltration by inhibiting NF-κB activation and proinflammatory cytokines in streptozotocin induced-diabetic nephropathy

(2011) Vivian Soetikno et al.   Nutrition & Metabolism

Effect of Thiazolidinediones on Albuminuria and Proteinuria in Diabetes: A Meta-analysis

(2010) Pantelis A. Sarafidis et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function

(2010) Gavin I. Welsh et al.   Cell Metabolism

Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose-fed rats

(2010) Jian-Mei Li et al.   HEPATOLOGY

Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes

(2010) Iain J Gallagher et al.   Genome Medicine

Ketohexokinase-Dependent Metabolism of Fructose Induces Proinflammatory Mediators in Proximal Tubular Cells

(2009) P. Cirillo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Curcumin produces neuroprotective effects via activating brain-derived neurotrophic factor/TrkB-dependent MAPK and PI-3K cascades in rodent cortical neurons

(2009) Rui Wang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Interaction of diet and diabetes on cardiovascular function in rats

(2008) Susan A. Marsh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Change in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathy

(2008) K Tikoo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Podocyte-Specific Deletion of Dicer Alters Cytoskeletal Dynamics and Causes Glomerular Disease

(2008) S. J. Harvey et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Podocyte-Specific Loss of Functional MicroRNAs Leads to Rapid Glomerular and Tubular Injury

(2008) J. Ho et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Podocyte-Selective Deletion of Dicer Induces Proteinuria and Glomerulosclerosis

(2008) S. Shi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY