Key Factors Governing Initial Stages of Lipid Droplet Formation

Fat inclusions strongly alter membrane mechanics

(2021) Alexandre Santinho et al.   BIOPHYSICAL JOURNAL

Seipin traps triacylglycerols to facilitate their nanoscale clustering in the endoplasmic reticulum membrane

(2021) Xavier Prasanna et al.   PLOS BIOLOGY

Seipin accumulates and traps diacylglycerols and triglycerides in its ring-like structure

(2021) Valeria Zoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets

(2021) Valeria Zoni et al.   eLife

Physical Characterization of Triolein and Implications for Its Role in Lipid Droplet Biogenesis

(2021) Siyoung Kim et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Membrane Curvature Catalyzes Lipid Droplet Assembly

(2020) Alexandre Santinho et al.   CURRENT BIOLOGY

Neutral lipids regulate amphipathic helix affinity for model lipid droplets

(2020) Aymeric Chorlay et al.   JOURNAL OF CELL BIOLOGY

Membrane Asymmetry Imposes Directionality on Lipid Droplet Emergence from the ER

(2019) Aymeric Chorlay et al.   DEVELOPMENTAL CELL

Seipin Facilitates Triglyceride Flow to Lipid Droplet and Counteracts Droplet Ripening via Endoplasmic Reticulum Contact

(2019) Veijo T. Salo et al.   DEVELOPMENTAL CELL

LDAF1 and Seipin Form a Lipid Droplet Assembly Complex

(2019) Jeeyun Chung et al.   DEVELOPMENTAL CELL

An Asymmetry in Monolayer Tension Regulates Lipid Droplet Budding Direction

(2018) Aymeric Chorlay et al.   BIOPHYSICAL JOURNAL

Dynamics and functions of lipid droplets

(2018) James A. Olzmann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Analyzing and Driving Cluster Formation in Atomistic Simulations

(2017) Gareth A. Tribello et al.   Journal of Chemical Theory and Computation

The physics of lipid droplet nucleation, growth and budding

(2016) Abdou Rachid Thiam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field

(2015) Jumin Lee et al.   Journal of Chemical Theory and Computation

A Time-Independent Free Energy Estimator for Metadynamics

(2014) Pratyush Tiwary et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Role of Flippases, Scramblases and Transfer Proteins in Phosphatidylserine Subcellular Distribution

(2014) Hannah M. Hankins et al.   TRAFFIC

Conical Lipids in Flat Bilayers Induce Packing Defects Similar to that Induced by Positive Curvature

(2013) Lydie Vamparys et al.   BIOPHYSICAL JOURNAL

PLUMED 2: New feathers for an old bird

(2013) Gareth A. Tribello et al.   COMPUTER PHYSICS COMMUNICATIONS

The biophysics and cell biology of lipid droplets

(2013) Abdou Rachid Thiam et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites

(2011) Jingyi Gong et al.   JOURNAL OF CELL BIOLOGY

MDAnalysis: A toolkit for the analysis of molecular dynamics simulations

(2011) Naveen Michaud-Agrawal et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Adsorption of Egg Phosphatidylcholine to an Air/Water and Triolein/Water Bubble Interface: Use of the 2-Dimensional Phase Rule To Estimate the Surface Composition of a Phospholipid/Triolein/Water Surface as a Function of Surface Pressure

(2010) Matthew A. Mitsche et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Triglyceride Blisters in Lipid Bilayers: Implications for Lipid Droplet Biogenesis and the Mobile Lipid Signal in Cancer Cell Membranes

(2010) Himanshu Khandelia et al.   PLoS One

Reconstructing the equilibrium Boltzmann distribution from well-tempered metadynamics

(2009) M. Bonomi et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Minireview: Lipid Droplets in Lipogenesis and Lipolysis

(2008) Nicole A. Ducharme et al.   ENDOCRINOLOGY

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Well-Tempered Metadynamics: A Smoothly Converging and Tunable Free-Energy Method

(2008) Alessandro Barducci et al.   PHYSICAL REVIEW LETTERS

P-LINCS:  A Parallel Linear Constraint Solver for Molecular Simulation

(2007) Berk Hess   Journal of Chemical Theory and Computation