Combination strategies to maximize the benefits of cancer immunotherapy
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Title
Combination strategies to maximize the benefits of cancer immunotherapy
Authors
Keywords
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Journal
Journal of Hematology & Oncology
Volume 14, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-09-28
DOI
10.1186/s13045-021-01164-5
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- Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma and Indolent B-Cell Malignancies Can Be Effectively Treated With Autologous T Cells Expressing an Anti-CD19 Chimeric Antigen Receptor
- (2015) James N. Kochenderfer et al. JOURNAL OF CLINICAL ONCOLOGY
- VEGF-A modulates expression of inhibitory checkpoints on CD8+T cells in tumors
- (2015) Thibault Voron et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Carbon-ion beams induce production of an immune mediator protein, high mobility group box 1, at levels comparable with X-ray irradiation
- (2015) Y. Yoshimoto et al. JOURNAL OF RADIATION RESEARCH
- A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16ecto directed chimeric antigen receptors for recurrent ovarian cancer
- (2015) Mythili Koneru et al. Journal of Translational Medicine
- T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
- (2015) Daniel W Lee et al. LANCET
- 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
- (2015) Adrienne H Long et al. NATURE MEDICINE
- Nivolumab and Ipilimumab versus Ipilimumab in Untreated Melanoma
- (2015) Michael A. Postow et al. NEW ENGLAND JOURNAL OF MEDICINE
- Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma
- (2015) James Larkin et al. NEW ENGLAND JOURNAL OF MEDICINE
- Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
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- Development and Characterization of Bladder Cancer Patient-Derived Xenografts for Molecularly Guided Targeted Therapy
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- Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing
- (2015) Sofia R. Gameiro et al. Oncotarget
- Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity
- (2014) Jason W. Griffith et al. Annual Review of Immunology
- Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease
- (2014) Mark D. Turner et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Armed Oncolytic Virus Enhances Immune Functions of Chimeric Antigen Receptor-Modified T Cells in Solid Tumors
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- Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1 and are more susceptible to cyclophosphamide-induced apoptosis
- (2014) Sarah Dimeloe et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
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- Cutting Edge: Autocrine TGF- Sustains Default Tolerogenesis by IDO-Competent Dendritic Cells
- (2014) M. L. Belladonna et al. JOURNAL OF IMMUNOLOGY
- CD47 Signaling Regulates the Immunosuppressive Activity of VEGF in T Cells
- (2014) Sukhbir Kaur et al. JOURNAL OF IMMUNOLOGY
- MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial
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- Nanomicelle formulation modifies the pharmacokinetic profiles and cardiac toxicity of daunorubicin
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- Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors
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- Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
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- Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia
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- Localized Oncolytic Virotherapy Overcomes Systemic Tumor Resistance to Immune Checkpoint Blockade Immunotherapy
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- Oncolytic Viruses and Their Application to Cancer Immunotherapy
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- Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes
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- Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation
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- Role of Macrophage Targeting in the Antitumor Activity of Trabectedin
- (2013) Giovanni Germano et al. CANCER CELL
- An Intact Immune System Is Required for the Anticancer Activities of Histone Deacetylase Inhibitors
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- A Chimeric Receptor with NKG2D Specificity Enhances Natural Killer Cell Activation and Killing of Tumor Cells
- (2013) Y.-H. Chang et al. CANCER RESEARCH
- Oncology Meets Immunology: The Cancer-Immunity Cycle
- (2013) Daniel S. Chen et al. IMMUNITY
- Radiation-induced loss of cell surface CD47 enhances immune-mediated clearance of human papillomavirus-positive cancer
- (2013) Daniel W. Vermeer et al. INTERNATIONAL JOURNAL OF CANCER
- The Narrow-Spectrum HDAC Inhibitor Entinostat Enhances NKG2D Expression Without NK Cell Toxicity, Leading to Enhanced Recognition of Cancer Cells
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- The role of IL-6 in the radiation response of prostate cancer
- (2013) Chun-Te Wu et al. Radiation Oncology
- Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors
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- Phase I/II Trial of Carboplatin and Paclitaxel Chemotherapy in Combination with Intravenous Oncolytic Reovirus in Patients with Advanced Malignancies
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- The CD47–SIRPα pathway in cancer immune evasion and potential therapeutic implications
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- Gr-1+CD11b+ cells are responsible for tumor promoting effect of TGF-β in breast cancer progression
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- Interdisciplinary Critique of Sipuleucel-T as Immunotherapy in Castration-Resistant Prostate Cancer
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- Tumor-targeting multifunctional micelles for imaging and chemotherapy of advanced bladder cancer
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- Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma
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- Chemotherapeutics and Radiation Stimulate MHC Class I Expression through Elevated Interferon-beta Signaling in Breast Cancer Cells
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- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
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- Tumor infiltration by chemokine receptor 7 (CCR7)+T-lymphocytes is a favorable prognostic factor in metastatic colorectal cancer
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- Radiation-induced effects and the immune system in cancer
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- Unraveling Cancer Chemoimmunotherapy Mechanisms by Gene and Protein Expression Profiling of Responses to Cyclophosphamide
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- Current status of multiple antigen-presenting peptide vaccine systems: Application of organic and inorganic nanoparticles
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- VEGF directly suppresses activation of T cells from ovarian cancer patients and healthy individuals via VEGF receptor Type 2
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- Targeted delivery of oligonucleotides into tumor-associated macrophages for cancer immunotherapy
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- Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study
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- CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
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- Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
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- gp100 Peptide Vaccine and Interleukin-2 in Patients with Advanced Melanoma
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- Innate or Adaptive Immunity? The Example of Natural Killer Cells
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- Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
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- 5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity
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- Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages
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- In Situ Vaccination With a TLR9 Agonist Induces Systemic Lymphoma Regression: A Phase I/II Study
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- Surface antigens analysis reveals significant expression of candidate targets for immunotherapy in adult acute lymphoid leukemia
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- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
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- Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer
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- Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome
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- Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti-CTLA-4 Antibody
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- Cutting Edge: Vascular Endothelial Growth Factor-Mediated Signaling in Human CD45RO+ CD4+ T Cells Promotes Akt and ERK Activation and Costimulates IFN- Production
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- Optimal induction of HPV DNA vaccine-induced CD8+ T cell responses and therapeutic antitumor effect by antigen engineering and electroporation
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