ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer
Authors
Keywords
-
Journal
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 41, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-01-08
DOI
10.1186/s13046-021-02229-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Wnt-mediated endothelial transformation into mesenchymal stem cell–like cells induces chemoresistance in glioblastoma
- (2020) Menggui Huang et al. Science Translational Medicine
- LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes
- (2020) Cefan Zhou et al. Molecular Cancer
- Targeting Glucose Metabolism to Overcome Resistance to Anticancer Chemotherapy in Breast Cancer
- (2020) Elizabeth Varghese et al. Cancers
- Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates
- (2020) Nan Wang et al. CELL
- B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2
- (2019) Tongguo Shi et al. Cell Death & Disease
- Circulating biomarkers for early detection and clinical management of colorectal cancer
- (2019) María Marcuello et al. MOLECULAR ASPECTS OF MEDICINE
- Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis
- (2019) Peiwei Huangyang et al. Cell Metabolism
- The prognostic role of circulating tumor cells in colorectal cancer
- (2019) Lahiri Kanth Nanduri et al. Expert Review of Anticancer Therapy
- How the Warburg effect supports aggressiveness and drug resistance of cancer cells?
- (2018) Philippe Icard et al. DRUG RESISTANCE UPDATES
- Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway
- (2018) Yen-Hsiu Yeh et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- PTBP1 knockdown overcomes the resistance to vincristine and oxaliplatin in drug-resistant colon cancer cells through regulation of glycolysis
- (2018) Chuanyao Cheng et al. BIOMEDICINE & PHARMACOTHERAPY
- EBV reduces autophagy, intracellular ROS and mitochondria to impair monocyte survival and differentiation
- (2018) M.S. Gilardini Montani et al. Autophagy
- Early redox activities modulate Xenopus tail regeneration
- (2018) Fernando Ferreira et al. Nature Communications
- Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells
- (2018) Don Benjamin et al. Cell Reports
- Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer
- (2017) Luisa Iommarini et al. Frontiers in Oncology
- Identification of Targets of the HIF-1 Inhibitor IDF-11774 Using Alkyne-Conjugated Photoaffinity Probes
- (2016) Hyun Seung Ban et al. BIOCONJUGATE CHEMISTRY
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- PI3K inhibitor LY294002, as opposed to wortmannin, enhances AKT phosphorylation in gemcitabine-resistant pancreatic cancer cells
- (2016) Yufeng Wang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Amplification of USP13 drives ovarian cancer metabolism
- (2016) Cecil Han et al. Nature Communications
- Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling
- (2016) So-Young Hwang et al. Cell Reports
- Fundamentals of cancer metabolism
- (2016) R. J. DeBerardinis et al. Science Advances
- PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth
- (2015) Emily D. Montal et al. MOLECULAR CELL
- Intensive follow-up strategies improve outcomes in nonmetastatic colorectal cancer patients after curative surgery: a systematic review and meta-analysis
- (2014) S. Pita-Fernandez et al. ANNALS OF ONCOLOGY
- Echinomycin protects mice against relapsed acute myeloid leukemia without adverse effect on hematopoietic stem cells
- (2014) Y. Wang et al. BLOOD
- Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer
- (2014) K. T. Pate et al. EMBO JOURNAL
- Genetic Markers of Toxicity From Capecitabine and Other Fluorouracil-Based Regimens: Investigation in the QUASAR2 Study, Systematic Review, and Meta-Analysis
- (2014) Dan Rosmarin et al. JOURNAL OF CLINICAL ONCOLOGY
- Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma
- (2014) Robert T. Wicks et al. NEURO-ONCOLOGY
- Lactic Acidosis
- (2014) Jeffrey A. Kraut et al. NEW ENGLAND JOURNAL OF MEDICINE
- The pentose phosphate pathway and cancer
- (2014) Krushna C. Patra et al. TRENDS IN BIOCHEMICAL SCIENCES
- Red fluorescent genetically encoded indicator for intracellular hydrogen peroxide
- (2014) Yulia G. Ermakova et al. Nature Communications
- Downregulation of MCT1 inhibits tumor growth, metastasis and enhances chemotherapeutic efficacy in osteosarcoma through regulation of the NF-κB pathway
- (2013) Zhiqiang Zhao et al. CANCER LETTERS
- Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress
- (2012) Z. Unnisa et al. BLOOD
- Wnt/β-Catenin Signaling and Disease
- (2012) Hans Clevers et al. CELL
- Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression
- (2012) Tom Latham et al. NUCLEIC ACIDS RESEARCH
- Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer
- (2012) A. Kreso et al. SCIENCE
- TCF/LEFs and Wnt Signaling in the Nucleus
- (2012) K. M. Cadigan et al. Cold Spring Harbor Perspectives in Biology
- Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice
- (2010) Hua-shan Shi et al. CANCER SCIENCE
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started