Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM

An extracytoplasmic protein and a moonlighting enzyme modulate synthesis of c‐di‐AMP in Listeria monocytogenes

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Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM

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Crystal structures of the c-di-AMP synthesizing enzyme CdaA

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Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus

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Making and breaking of an essential poison: the cyclases and phosphodiesterases that produce and degrade the essential second messenger cyclic di-AMP in bacteria

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c-di-AMP modulatesListeria monocytogenescentral metabolism to regulate growth, antibiotic resistance and osmoregulation

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(2017) Petya Violinova Krasteva et al.   Nature Chemical Biology

Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP inBacillus subtilis

(2017) Jan Gundlach et al.   Science Signaling

Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP inBacillus subtilis

(2017) Jan Gundlach et al.   Science Signaling

c-di-AMP: An Essential Molecule in the Signaling Pathways that Regulate the Viability and Virulence of Gram-Positive Bacteria

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CheckMyMetal: a macromolecular metal-binding validation tool

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Replenishing the cyclic-di-AMP pool: regulation of diadenylate cyclase activity in bacteria

(2016) Thi Huong Pham et al.   CURRENT GENETICS

Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC

(2016) TuAnh Ngoc Huynh et al.   MOLECULAR MICROBIOLOGY

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

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Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3′-dATP

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Phenotypes Associated with the Essential Diadenylate Cyclase CdaA and Its Potential Regulator CdaR in the Human Pathogen Listeria monocytogenes

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An Essential Poison: Synthesis and Degradation of Cyclic Di-AMP in Bacillus subtilis

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Bacterial Signal Transduction by Cyclic Di-GMP and Other Nucleotide Second Messengers

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Cross-talk between Two Nucleotide-signaling Pathways inStaphylococcus aureus

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Structural and Biochemical Analysis of the Essential Diadenylate Cyclase CdaA fromListeria monocytogenes

(2015) Jonathan Rosenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclic-di-AMP synthesis by the diadenylate cyclase CdaA is modulated by the peptidoglycan biosynthesis enzyme GlmM in L actococcus lactis

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An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence

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Functional analysis of the sporulation-specific diadenylate cyclase CdaS in Bacillus thuringiensis

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Control of the Diadenylate Cyclase CdaS inBacillus subtilis

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MicroScale Thermophoresis: Interaction analysis and beyond

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ConSurf: Using Evolutionary Data to Raise Testable Hypotheses about Protein Function

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Cyclic Di-AMP Impairs Potassium Uptake Mediated by a Cyclic Di-AMP Binding Protein in Streptococcus pneumoniae

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Solution Structure of the PAS Domain of a Thermophilic YybT Protein Homolog Reveals a Potential Ligand-binding Site

(2013) Edward Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclic di-AMP: another second messenger enters the fray

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Mutation in the C-Di-AMP Cyclase dacA Affects Fitness and Resistance of Methicillin Resistant Staphylococcus aureus

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Systematic identification of conserved bacterial c-di-AMP receptor proteins

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Cyclic di-AMP Is Critical for Listeria monocytogenes Growth, Cell Wall Homeostasis, and Establishment of Infection

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Cyclic Di-AMP Homeostasis inBacillus subtilis

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c-di-AMP reports DNA integrity during sporulation in Bacillus subtilis

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Unusual Heme-Binding PAS Domain from YybT Family Proteins

(2011) F. Rao et al.   JOURNAL OF BACTERIOLOGY

Crystal Structure of Bacillus anthracis Phosphoglucosamine Mutase, an Enzyme in the Peptidoglycan Biosynthetic Pathway

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LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

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Analysis of the role of Bacillus subtilis σM in β-lactam resistance reveals an essential role for c-di-AMP in peptidoglycan homeostasis

(2011) Yun Luo et al.   MOLECULAR MICROBIOLOGY

c-di-AMP Is a New Second Messenger in Staphylococcus aureus with a Role in Controlling Cell Size and Envelope Stress

(2011) Rebecca M. Corrigan et al.   PLoS Pathogens

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c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

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YybT Is a Signaling Protein That Contains a Cyclic Dinucleotide Phosphodiesterase Domain and a GGDEF Domain with ATPase Activity

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Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates

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