Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds

Combining genetic algorithm with machine learning strategies for designing potent antimicrobial peptides

(2021) Kyle Boone et al.   BMC BIOINFORMATICS

In Vitro Evaluation of Five Antimicrobial Peptides against the Plant Pathogen Erwinia amylovora

(2021) Rafael J. Mendes et al.   Biomolecules

Physicochemical Features and Peculiarities of Interaction of AMP with the Membrane

(2021) Malak Pirtskhalava et al.   Pharmaceuticals

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

(2020) Shuai Xia et al.   CELL RESEARCH

Antiviral Peptides: Identification and Validation

(2020) Garima Agarwal et al.   International Journal of Peptide Research and Therapeutics

NP213 (Novexatin®): A unique therapy candidate for onychomycosis with a differentiated safety and efficacy profile

(2020) Derry K Mercer et al.   MEDICAL MYCOLOGY

Dietary supplementation of recombinant antimicrobial peptide Epinephelus lanceolatus piscidin improves growth performance and immune response in Gallus gallus domesticus

(2020) Hsueh-Ming Tai et al.   PLoS One

Antimicrobial peptides as therapeutic agents: opportunities and challenges

(2020) Margit Mahlapuu et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

A New Era of Antibiotics: The Clinical Potential of Antimicrobial Peptides

(2020) Katrina Browne et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain

(2020) Victor K. Outlaw et al.   mBio

De Novo Designed Amphipathic α-Helical Antimicrobial Peptides Incorporating Dab and Dap Residues on the Polar Face To Treat the Gram-Negative Pathogen, Acinetobacter baumannii

(2019) Colin T. Mant et al.   JOURNAL OF MEDICINAL CHEMISTRY

Vibrio spp. from Yesso scallop ( Patinopecten yessoensis ) demonstrating virulence properties and antimicrobial resistance

(2019) B. C. J. De Silva et al.   JOURNAL OF FOOD SAFETY

Application of Antimicrobial Peptides of the Innate Immune System in Combination With Conventional Antibiotics—A Novel Way to Combat Antibiotic Resistance?

(2019) Maria S. Zharkova et al.   Frontiers in Cellular and Infection Microbiology

Antiviral peptides as promising therapeutic drugs

(2019) Liana Costa Pereira Vilas Boas et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Exploring small cationic peptides of different origin as potential antimicrobial agents in aquaculture

(2019) Rosa León et al.   FISH & SHELLFISH IMMUNOLOGY

Bacterial resistance to antimicrobial peptides

(2019) Milad Abdi et al.   JOURNAL OF PEPTIDE SCIENCE

Effects of the peptide H-OOWW-NH2 and its derived lipopeptide C12-OOWW-NH2 on controlling of citrus postharvest green mold

(2019) Xindan Li et al.   POSTHARVEST BIOLOGY AND TECHNOLOGY

Joker: An algorithm to insert patterns into sequences for designing antimicrobial peptides

(2018) William F. Porto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Bacterial biofilm and associated infections

(2018) Muhsin Jamal et al.   Journal of the Chinese Medical Association

Histidine-rich Modification of a Scorpion-derived Peptide Improves Bioavailability and Inhibitory Activity against HSV-1

(2018) Zhengyang Zeng et al.   Theranostics

Antimicrobial Peptides and Their Therapeutic Potential for Bacterial Skin Infections and Wounds

(2018) Anja Pfalzgraff et al.   Frontiers in Pharmacology

Cathelicidin-Derived Antimicrobial Peptides Inhibit Zika Virus Through Direct Inactivation and Interferon Pathway

(2018) Miao He et al.   Frontiers in Immunology

EmPis-1L, an Effective Antimicrobial Peptide Against the Antibiotic-Resistant VBNC State Cells of Pathogenic Bacteria

(2018) Bochao Hu et al.   Probiotics and Antimicrobial Proteins

Antimicrobial peptides from different plant sources: Isolation, characterisation, and purification

(2018) Swee-Seong Tang et al.   PHYTOCHEMISTRY

Peptide based antimicrobials: Design strategies and therapeutic potential

(2018) Prakash Kishore Hazam et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Caerin1.1 Suppresses the Growth of Porcine Epidemic Diarrhea Virus In Vitro via Direct Binding to the Virus

(2018) Nan Guo et al.   Viruses-Basel

Molecular farming of antimicrobial peptides: available platforms and strategies for improving protein biosynthesis using modified virus vectors

(2018) MICHEL L. LEITE et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Colistin versus polymyxin B for the treatment of patients with multidrug-resistant Gram-negative infections: a systematic review and meta-analysis

(2017) Konstantinos Z. Vardakas et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Structure and antibacterial activities of new cyclic peptide antibiotics, pargamicins B, C and D, from Amycolatopsis sp. ML1-hF4

(2017) Hideki Hashizume et al.   JOURNAL OF ANTIBIOTICS

Antimicrobial packaging based on ɛ-polylysine bioactive film for the control of mycotoxigenic fungi in vitro and in bread

(2017) C. Luz et al.   JOURNAL OF FOOD PROCESSING AND PRESERVATION

Cyclic Peptides as Novel Therapeutic Microbicides: Engineering of Human Defensin Mimetics

(2017) Annarita Falanga et al.   MOLECULES

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

(2017) Tanja Florin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

(2017) Tanja Florin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species

(2017) Enea Sancho-Vaello et al.   Scientific Reports

Molecular mechanism of synergy between the antimicrobial peptides PGLa and magainin 2

(2017) Jonathan Zerweck et al.   Scientific Reports

Combination Effects of Antimicrobial Peptides

(2016) Guozhi Yu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Collagencin, an antibacterial peptide from fish collagen: Activity, structure and interaction dynamics with membrane

(2016) Nadia Ennaas et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antimicrobial peptides and their interaction with biofilms of medically relevant bacteria

(2016) Giovanna Batoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Anti-biofilm peptides as a new weapon in antimicrobial warfare

(2016) Daniel Pletzer et al.   CURRENT OPINION IN MICROBIOLOGY

Oligomerization of the antimicrobial peptide Protegrin-5 in a membrane-mimicking environment. Structural studies by high-resolution NMR spectroscopy

(2016) Konstantin S. Usachev et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Pharmacokinetics/pharmacodynamics of colistin and polymyxin B: are we there yet?

(2016) Thien B. Tran et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Marine Antimicrobial Peptides: Nature Provides Templates for the Design of Novel Compounds against Pathogenic Bacteria

(2016) Annarita Falanga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Activity of tick antimicrobial peptide from Ixodes persulcatus (persulcatusin) against cell membranes of drug-resistant Staphylococcus aureus

(2016) Naruhide Miyoshi et al.   JOURNAL OF ANTIBIOTICS

Role of Aromatic Amino Acids in Lipopolysaccharide and Membrane Interactions of Antimicrobial Peptides for Use in Plant Disease Control

(2016) Aritreyee Datta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antimicrobial Peptides: Mechanisms of Action and Resistance

(2016) B. Bechinger et al.   JOURNAL OF DENTAL RESEARCH

The therapeutic applications of antimicrobial peptides (AMPs): a patent review

(2016) Hee-Kyoung Kang et al.   JOURNAL OF MICROBIOLOGY

Biofilms: an emergent form of bacterial life

(2016) Hans-Curt Flemming et al.   NATURE REVIEWS MICROBIOLOGY

Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition

(2016) Matthieu G. Gagnon et al.   NUCLEIC ACIDS RESEARCH

Functional structure and antimicrobial activity of persulcatusin, an antimicrobial peptide from the hard tick Ixodes persulcatus

(2016) Naruhide Miyoshi et al.   Parasites & Vectors

Bacterial strategies of resistance to antimicrobial peptides

(2016) Hwang-Soo Joo et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Defensins: The Case for Their Use against Mycobacterial Infections

(2016) Haodi Dong et al.   Journal of Immunology Research

Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

(2016) Ingrid A. Edwards et al.   ACS Infectious Diseases

Characterization of antimicrobial activity and mechanisms of low amphipathic peptides with different α-helical propensity

(2015) Xin Zhu et al.   Acta Biomaterialia

Antimicrobial peptide production and plant-based expression systems for medical and agricultural biotechnology

(2015) Edita Holaskova et al.   BIOTECHNOLOGY ADVANCES

Antimicrobial Peptide Structure and Mechanism of Action: A Focus on the Role of Membrane Structure

(2015) Tzong-Hsien Lee et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Lipoglycopeptide Antibacterial Agents in Gram-Positive Infections: A Comparative Review

(2015) Françoise Van Bambeke   DRUGS

Prevalence and Antimicrobial Resistance of Vibrio parahaemolyticus Isolated from Raw Shellfish in Poland

(2015) MAGDALENA LOPATEK et al.   JOURNAL OF FOOD PROTECTION

Marine Peptides: Bioactivities and Applications

(2015) Randy Cheung et al.   Marine Drugs

DBAASP v.2: an enhanced database of structure and antimicrobial/cytotoxic activity of natural and synthetic peptides

(2015) Malak Pirtskhalava et al.   NUCLEIC ACIDS RESEARCH

Cysteine-stabilized αβ defensins: From a common fold to antibacterial activity

(2015) Renata de Oliveira Dias et al.   PEPTIDES

Virocidal activity of Egyptian scorpion venoms against hepatitis C virus

(2015) Alaa MH El-Bitar et al.   Virology Journal

Antimicrobial Peptides: Insights into Membrane Permeabilization, Lipopolysaccharide Fragmentation and Application in Plant Disease Control

(2015) Aritreyee Datta et al.   Scientific Reports

Strategies employed in the design and optimization of synthetic antimicrobial peptide amphiphiles with enhanced therapeutic potentials

(2014) Zhan Yuin Ong et al.   ADVANCED DRUG DELIVERY REVIEWS

Inhibitory activity and molecular mechanism of protegrin-1 against porcine reproductive and respiratory syndrome virus in vitro

(2014) Chunhe Guo et al.   ANTIVIRAL THERAPY

Quorum Sensing Inhibitors as Anti-Biofilm Agents

(2014) Gilles Brackman et al.   CURRENT PHARMACEUTICAL DESIGN

Copsin, a Novel Peptide-based Fungal Antibiotic Interfering with the Peptidoglycan Synthesis

(2014) Andreas Essig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment

(2014) Stefano Vanni et al.   Nature Communications

Benefits and risks of antimicrobial use in food-producing animals

(2014) Haihong Hao et al.   Frontiers in Microbiology

Treatment of microbial biofilms in the post-antibiotic era: prophylactic and therapeutic use of antimicrobial peptides and their design by bioinformatics tools

(2014) Mariagrazia Di Luca et al.   Pathogens and Disease

Chimeric Beta-Defensin Analogs, Including the Novel 3NI Analog, Display Salt-Resistant Antimicrobial Activity and Lack Toxicity in Human Epithelial Cell Lines

(2013) Olga Scudiero et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Plant antimicrobial peptides

(2013) Robert Nawrot et al.   FOLIA MICROBIOLOGICA

The Cyclic Cystine Ladder in θ-Defensins Is Important for Structure and Stability, but Not Antibacterial Activity

(2013) Anne C. Conibear et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ohmyungsamycins A and B: Cytotoxic and Antimicrobial Cyclic Peptides Produced by Streptomyces sp. from a Volcanic Island

(2013) Soohyun Um et al.   JOURNAL OF ORGANIC CHEMISTRY

Pleurocidin, a novel antimicrobial peptide, induces human mast cell activation through the FPRL1 receptor

(2013) P Pundir et al.   Mucosal Immunology

A new antibacterial lipopeptide found by UPLC-MS from an actinomyceteStreptomycessp. HCCB10043

(2013) Min Rao et al.   NATURAL PRODUCT RESEARCH

Dietary Nisin Modulates the Gastrointestinal Microbial Ecology and Enhances Growth Performance of the Broiler Chickens

(2013) Damian Józefiak et al.   PLoS One

From antimicrobial to anticancer peptides. A review

(2013) Diana Gaspar et al.   Frontiers in Microbiology

Chemical synthesis and biological evaluation of an antimicrobial peptide gonococcal growth inhibitor

(2012) John D. Wade et al.   AMINO ACIDS

Effects of dietary supplementation of antimicrobial peptide-A3 on growth performance, nutrient digestibility, intestinal and fecal microflora and intestinal morphology in weanling pigs

(2012) J.H. Yoon et al.   ANIMAL FEED SCIENCE AND TECHNOLOGY

Inhibition of Bacterial Biofilm Formation and Swarming Motility by a Small Synthetic Cationic Peptide

(2012) César de la Fuente-Núñez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structural Characterization of the Cyclic Cystine Ladder Motif of θ-Defensins

(2012) Anne C. Conibear et al.   BIOCHEMISTRY

Lipid shape is a key factor for membrane interactions of amphipathic helical peptides

(2012) Erik Strandberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Recombinant expression and purification of the antimicrobial peptide magainin-2

(2012) Reinaldo Ramos et al.   BIOTECHNOLOGY PROGRESS

Potential novel therapeutic strategies in cystic fibrosis: antimicrobial and anti-biofilm activity of natural and designed α-helical peptides against Staphylococcus aureus, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia

(2012) Arianna Pompilio et al.   BMC MICROBIOLOGY

A comprehensive summary of LL-37, the factotum human cathelicidin peptide

(2012) Dieter Vandamme et al.   CELLULAR IMMUNOLOGY

Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance

(2012) M. Hassan et al.   JOURNAL OF APPLIED MICROBIOLOGY

Broad Antiviral Activity and Crystal Structure of HIV-1 Fusion Inhibitor Sifuvirtide

(2012) Xue Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rationally Designed α-Helical Broad-Spectrum Antimicrobial Peptides with Idealized Facial Amphiphilicity

(2012) Nikken Wiradharma et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Pediocins: The bacteriocins of Pediococci. Sources, production, properties and applications

(2012) Maria Papagianni et al.   Microbial Cell Factories

Expression systems for heterologous production of antimicrobial peptides

(2012) Nádia Skorupa Parachin et al.   PEPTIDES

Effects of the antimicrobial peptide cecropin AD on performance and intestinal health in weaned piglets challenged with Escherichia coli

(2012) Shudan Wu et al.   PEPTIDES

Overview on the recent study of antimicrobial peptides: Origins, functions, relative mechanisms and application

(2012) Yanmei Li et al.   PEPTIDES

Role of lipids in the interaction of antimicrobial peptides with membranes

(2012) Vitor Teixeira et al.   PROGRESS IN LIPID RESEARCH

Plant storage proteins with antimicrobial activity: novel insights into plant defense mechanisms

(2011) Elizabete de Souza Cândido et al.   FASEB JOURNAL

Peptides from Royal Jelly: studies on the antimicrobial activity of jelleins, jelleins analogs and synergy with temporins

(2011) Alessandra Romanelli et al.   JOURNAL OF PEPTIDE SCIENCE

Virucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses

(2011) Qiaoli Li et al.   PEPTIDES

Identification of Botryticidal Proteins with Similarity to NBS–LRR Proteins in Rosemary Pepper (Lippia sidoides Cham.) Flowers

(2011) João S. Moreira et al.   PROTEIN JOURNAL

The expanding scope of antimicrobial peptide structures and their modes of action

(2011) Leonard T. Nguyen et al.   TRENDS IN BIOTECHNOLOGY

Expression of cecropin B in Pichia pastoris and its bioactivity in vitro

(2011) XIUQING WANG et al.   Experimental and Therapeutic Medicine

Novel Synthetic, Salt-Resistant Analogs of Human Beta-Defensins 1 and 3 Endowed with Enhanced Antimicrobial Activity

(2010) O. Scudiero et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Advances in plant molecular farming

(2010) Olawole O. Obembe et al.   BIOTECHNOLOGY ADVANCES

Primary structure and cellular localization of callinectin, an antimicrobial peptide from the blue crab

(2010) Edward J. Noga et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Review article: Commercialization of whole-plant systems for biomanufacturing of protein products: evolution and prospects

(2010) H. Maelor Davies   PLANT BIOTECHNOLOGY JOURNAL

Swine intestine antimicrobial peptides inhibit infectious bronchitis virus infectivity in chick embryos

(2010) Q. Sun et al.   POULTRY SCIENCE

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

The importance of plant health to food security

(2010) Julie Flood   Food Security

Alpha-helical cationic antimicrobial peptides: relationships of structure and function

(2010) Yibing Huang et al.   Protein & Cell

Sifuvirtide, a potent HIV fusion inhibitor peptide

(2009) Rui-Rui Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Solution NMR studies of amphibian antimicrobial peptides: Linking structure to function?

(2009) Evan F. Haney et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A novel antifungal hevein-type peptide fromTriticum kiharaeseeds with a unique 10-cysteine motif

(2009) Tatyana I. Odintsova et al.   FEBS Journal

A peptidomics study reveals the impressive antimicrobial peptide arsenal of the wax moth Galleria mellonella

(2009) Susan E. Brown et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Production of bioactive human α-defensin 5 in Pichia pastoris

(2009) Kung-Hao Hsu et al.   JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY

Antibacterial activity of recombinant hCAP18/LL37 protein secreted from Pichia pastoris

(2009) Soon-ja Kim et al.   JOURNAL OF MICROBIOLOGY

Application of antimicrobial peptides in agriculture and food industry

(2009) Keykhosrow Keymanesh et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Incorporation of a Hydrophobic Antibacterial Peptide into Amphiphilic Polyelectrolyte Multilayers: A Bioinspired Approach to Prepare Biocidal Thin Coatings

(2008) Aurélie Guyomard et al.   ADVANCED FUNCTIONAL MATERIALS

Effects of dietary supplementation with an expressed fusion peptide bovine lactoferricin–lactoferrampin on performance, immune function and intestinal mucosal morphology in piglets weaned at age 21 d

(2008) Zhiru Tang et al.   BRITISH JOURNAL OF NUTRITION

Oyster hemocytes express a proline-rich peptide displaying synergistic antimicrobial activity with a defensin

(2008) Yannick Gueguen et al.   MOLECULAR IMMUNOLOGY

APD2: the updated antimicrobial peptide database and its application in peptide design

(2008) Guangshun Wang et al.   NUCLEIC ACIDS RESEARCH

Expression and characterization of antimicrobial peptide CecropinAD in the methylotrophic yeast Pichia pastoris

(2008) Feng-liang Jin et al.   PROCESS BIOCHEMISTRY

Discovery of six families of fungal defensin-like peptides provides insights into origin and evolution of the CSαβ defensins

(2007) Shunyi Zhu   MOLECULAR IMMUNOLOGY

Expression of active recombinant human lactoferrin in the milk of transgenic goats

(2007) Jie Zhang et al.   PROTEIN EXPRESSION AND PURIFICATION