Magnesium in renal fibrosis

Long noncoding RNA NEAT1 is involved in the protective effect of Klotho on renal tubular epithelial cells in diabetic kidney disease through the ERK1/2 signaling pathway

(2020) Yan-Lin Yang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

IRF‐1 promotes renal fibrosis by downregulation of Klotho

(2020) Yan Li et al.   FASEB JOURNAL

Serum magnesium, mortality and disease progression in chronic kidney disease

(2020) Rami Azem et al.   BMC Nephrology

TRPM7 contributes to progressive nephropathy

(2020) Sayuri Suzuki et al.   Scientific Reports

Blood Magnesium Level and Selected Oxidative Stress Indices in Lead-Exposed Workers

(2020) Magdalena Wyparło-Wszelaki et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Identification of histone deacetylase 8 as a novel therapeutic target for renal fibrosis

(2020) Yunhe Zhang et al.   FASEB JOURNAL

Normalization of magnesium deficiency attenuated mechanical allodynia, depressive-like behaviors, and memory deficits associated with cyclophosphamide-induced cystitis by inhibiting TNF-α/NF-κB signaling in female rats

(2020) Jia-Liang Chen et al.   Journal of Neuroinflammation

Dietary Magnesium Intake and Leukocyte Telomere Attrition in Adults: The Regulatory Role of Serum Tumor Necrosis Factor α

(2020) Jie Yu et al.   MEDIATORS OF INFLAMMATION

WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling

(2020) Xiaoyu Zhou et al.   Oxidative Medicine and Cellular Longevity

Isoliquiritigenin Attenuates UUO-Induced Renal Inflammation and Fibrosis by Inhibiting Mincle/Syk/NF-Kappa B Signaling Pathway

(2020) Yuan Liao et al.   Drug Design Development and Therapy

Increasing the Magnesium Concentration in Various Dialysate Solutions Differentially Modulates Oxidative Stress in a Human Monocyte Cell Line

(2020) Carmen Vida et al.   Antioxidants

Magnesium bioavailability of dried and thinly shaved kombu in rats

(2020) Manami Nishiyama et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model

(2020) Zhengzhou Shi et al.   Stem Cell Research & Therapy

Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells

(2020) Yan Li et al.   BMC Molecular and Cell Biology

Ibrolipim attenuates early-stage nephropathy in diet-induced diabetic minipigs: Focus on oxidative stress and fibrogenesis

(2020) Yi Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

The Transient Receptor Potential Melastatin 7 (TRPM7) Inhibitors Suppress Seizure-Induced Neuron Death by Inhibiting Zinc Neurotoxicity

(2020) Jeong Hyun Jeong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cathelicidin-BF attenuate kidney injury through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced diabetic rats

(2020) Yuan Liu et al.   LIFE SCIENCES

Chronic Oral Administration of Magnesium-L-Threonate Prevents Oxaliplatin-Induced Memory and Emotional Deficits by Normalization of TNF-α/NF-κB Signaling in Rats

(2020) Xin Zhou et al.   Neuroscience Bulletin

A study of Titanium and Magnesium particle-induced oxidative stress and toxicity to human osteoblasts

(2020) Niyou Wang et al.   Materials Science & Engineering C-Materials for Biological Applications

Oral Antioxidant Vitamins and Magnesium Limit Noise-Induced Hearing Loss by Promoting Sensory Hair Cell Survival: Role of Antioxidant Enzymes and Apoptosis Genes

(2020) Juan C. Alvarado et al.   Antioxidants

Magnesium lithospermate B protects the endothelium from inflammation-induced dysfunction through activation of Nrf2 pathway

(2019) Fei Gao et al.   ACTA PHARMACOLOGICA SINICA

The effects of magnesium-zinc-calcium-vitamin D co-supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes

(2019) Mehri Jamilian et al.   BMC Pregnancy and Childbirth

Magnesium lithospermate B improves renal hemodynamics and reduces renal oxygen consumption in 5/6th renal ablation/infarction rats

(2019) Pinglan Lin et al.   BMC Nephrology

Klotho recovery by genistein via promoter histone acetylation and DNA demethylation mitigates renal fibrosis in mice

(2019) Yanning Li et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Fetal neuroprotective mechanism of maternal magnesium sulfate for late gestation inflammation: in a rodent model

(2019) Nizar Khatib et al.   Journal of Maternal-Fetal & Neonatal Medicine

Effect of magnesium on reducing the UV-induced oxidative damage in marrow mesenchymal stem cells

(2019) Yangmei Chen et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis

(2019) Francisco J Rios et al.   CARDIOVASCULAR RESEARCH

KLF4 in Macrophages Attenuates TNFα-Mediated Kidney Injury and Fibrosis

(2019) Yi Wen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Protective Effect of Magnesium Lithospermate B on Hepatic Ischemia/Reperfusion via Inhibiting the Jak2/Stat3 Signaling Pathway

(2019) Ning Zhang et al.   Frontiers in Pharmacology

Magnesium isoglycyrrhizinate ameliorates fructose-induced podocyte apoptosis through downregulation of miR-193a to increase WT1

(2019) Tu-Shuai Li et al.   BIOCHEMICAL PHARMACOLOGY

Magnesium supplementation ameliorates toxic effects of 2,4-dichlorophenoxyacetic acid in rat model

(2019) S Shafeeq et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Magnesium-Induced Cell Survival Is Dependent on TRPM7 Expression and Function

(2019) Yuyang Sun et al.   MOLECULAR NEUROBIOLOGY

Role of Magnesium in Type 2 Diabetes Mellitus

(2019) Jianan Feng et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Magnesium lithospermate B attenuates renal injury in 5/6 renal ablation/infarction rats by mitochondrial pathway of apoptosis

(2019) Meng Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Ameliorative effect of Magnesium Isoglycyrrhizinate on hepatic encephalopathy by Epirubicin

(2019) Wenjiao Jiang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Magnesium prevents vascular calcification in Klotho deficiency

(2019) Anique D. ter Braake et al.   KIDNEY INTERNATIONAL

The Role of Magnesium in the Secondary Phase After Traumatic Spinal Cord Injury. A Prospective Clinical Observer Study

(2019) André Sperl et al.   Antioxidants

Inflammatory response to magnesium-based biodegradable implant materials

(2019) M.D. Costantino et al.   Acta Biomaterialia

Quercetin-induced yeast apoptosis through mitochondrial dysfunction under the accumulation of magnesium in Candida albicans

(2019) Min Seok Kwun et al.   Fungal Biology

Modified Magnesium Hydroxide Nanoparticles Inhibit the Inflammatory Response to Biodegradable Poly(lactide-co-glycolide) Implants

(2018) Eugene Lih et al.   ACS Nano

Versatile effects of magnesium hydroxide nanoparticles in PLGA scaffold–mediated chondrogenesis

(2018) Kwang-Sook Park et al.   Acta Biomaterialia

Magnesium sulfate differentially modulates fetal membrane inflammation in a time-dependent manner

(2018) Sarah N. Cross et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The inhibition of Hippo/Yap signaling pathway is required for magnesium isoglycyrrhizinate to ameliorate hepatic stellate cell inflammation and activation

(2018) Li Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Magnesium as a Neuroprotective Agent: A Review of Its Use in the Fetus, Term Infant with Neonatal Encephalopathy, and the Adult Stroke Patient

(2018) Ingran Lingam et al.   DEVELOPMENTAL NEUROSCIENCE

Protective effects of magnesium sulfate against doxorubicin induced cardiotoxicity in rats

(2018) Mina Khalilzadeh et al.   LIFE SCIENCES

Cellular and molecular mechanisms of kidney fibrosis

(2018) Sonja Djudjaj et al.   MOLECULAR ASPECTS OF MEDICINE

TRPM6 is Essential for Magnesium Uptake and Epithelial Cell Function in the Colon

(2018) Francesca Luongo et al.   Nutrients

Neuroprotective Effects of Magnesium Lithospermate B against Subarachnoid Hemorrhage in Rats

(2018) Yucong Peng et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Dietary magnesium deficiency impaired intestinal structural integrity in grass carp (Ctenopharyngodon idella)

(2018) Shuo-Peng Wei et al.   Scientific Reports

Low magnesium diet aggravates phosphate-induced kidney injury

(2018) Yusuke Sakaguchi et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Magnesium isoglycyrrhizinate alleviates liver injury in obese rats with acute necrotizing pancreatitis

(2018) Fangchao Mei et al.   PATHOLOGY RESEARCH AND PRACTICE

Magnesium isoglycyrrhizinate suppresses LPS-induced inflammation and oxidative stress through inhibiting NF-κB and MAPK pathways in RAW264.7 cells

(2018) Chunfeng Xie et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Magnesium induces preconditioning of the neonatal brain via profound mitochondrial protection

(2017) Gabriella Koning et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Magnesium Lithospermate B Suppresses Lipopolysaccharide-Induced Neuroinflammation in BV2 Microglial Cells and Attenuates Neurodegeneration in Lipopolysaccharide-Injected Mice

(2017) Yaojun Tai et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Rhein reverses Klotho repression via promoter demethylation and protects against kidney and bone injuries in mice with chronic kidney disease

(2017) Qin Zhang et al.   KIDNEY INTERNATIONAL

Recombinant α-Klotho may be prophylactic and therapeutic for acute to chronic kidney disease progression and uremic cardiomyopathy

(2017) Ming Chang Hu et al.   KIDNEY INTERNATIONAL

Chronic Kidney Disease

(2017) Angela C Webster et al.   LANCET

Magnesium isoglycyrrhizinate protects against renal-ischemia-reperfusion injury in a rat model via anti-inflammation, anti-oxidation and anti-apoptosis

(2017) Zhigang Zhao et al.   Molecular Medicine Reports

Magnesium isoglycyrrhizinate ameliorates doxorubicin‑induced acute cardiac and hepatic toxicity via anti‑oxidant and anti‑apoptotic mechanisms in mice

(2017) Zhonglin Wu et al.   Experimental and Therapeutic Medicine

Klotho mitigates cyclosporine A (CsA)-induced epithelial–mesenchymal transition (EMT) and renal fibrosis in rats

(2016) Qi-feng Liu et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival

(2016) Vladimir Chubanov et al.   eLife

The coordinated roles of miR-26a and miR-30c in regulating TGFβ1-induced epithelial-to-mesenchymal transition in diabetic nephropathy

(2016) Zongji Zheng et al.   Scientific Reports

Protective Effect of Astragaloside IV Against Paraquat-Induced Lung Injury in Mice by Suppressing Rho Signaling

(2015) Tong Chen et al.   INFLAMMATION

Effects of angiotensin II on transient receptor potential melastatin 7 channel function in cardiac fibroblasts

(2015) YANLI ZHOU et al.   Experimental and Therapeutic Medicine

Mycelia glycoproteins from Cordyceps sobolifera ameliorate cyclosporine-induced renal tubule dysfunction in rats

(2014) Charny-Cherng Chyau et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hypomagnesemia and the Risk of Death and GFR Decline in Chronic Kidney Disease

(2013) Steven Van Laecke et al.   AMERICAN JOURNAL OF MEDICINE

Dysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemia

(2011) Alvaro Yogi et al.   JOURNAL OF HYPERTENSION

Downregulation of Renal TRPM7 and Increased Inflammation and Fibrosis in Aldosterone-Infused Mice

(2008) Bruno Sontia et al.   HYPERTENSION