Magnesium Lithospermate B Suppresses Lipopolysaccharide-Induced Neuroinflammation in BV2 Microglial Cells and Attenuates Neurodegeneration in Lipopolysaccharide-Injected Mice

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

Pharmacological Modulation of Functional Phenotypes of Microglia in Neurodegenerative Diseases

(2017) Gyun Jee Song et al.   Frontiers in Aging Neuroscience

Microglia Responses in Acute and Chronic Neurological Diseases: What Microglia-Specific Transcriptomic Studies Taught (and did Not Teach) Us

(2017) Hélène E. Hirbec et al.   Frontiers in Aging Neuroscience

The Role of Microglia in Retinal Neurodegeneration: Alzheimer's Disease, Parkinson, and Glaucoma

(2017) Ana I. Ramirez et al.   Frontiers in Aging Neuroscience

Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain

(2016) Katarzyna Popiolek-Barczyk et al.   CURRENT MEDICINAL CHEMISTRY

Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway

(2016) Haroon Badshah et al.   Scientific Reports

How microglia kill neurons

(2015) Guy C. Brown et al.   BRAIN RESEARCH

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Beneficial effect of magnesium lithospermate B on cerebral ischemia–reperfusion injury in rats involves the regulation of miR-107/glutamate transporter 1 pathway

(2015) Zhong-Bao Yang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Microglia-Mediated Inflammation and Neurodegenerative Disease

(2015) Ling Xu et al.   MOLECULAR NEUROBIOLOGY

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

(2015) Yu Tang et al.   MOLECULAR NEUROBIOLOGY

Magnesium Lithospermate B Protects Neurons Against Amyloid β (1–42)-Induced Neurotoxicity Through the NF-κB Pathway

(2015) Feng Jiang et al.   NEUROCHEMICAL RESEARCH

Innate Immune Response in Brain, NF-Kappa B Signaling and Cystatins

(2015) Nataša Kopitar-Jerala   Frontiers in Molecular Neuroscience

Benfotiamine Attenuates Inflammatory Response in LPS Stimulated BV-2 Microglia

(2015) Iva Bozic et al.   PLoS One

Activation of BV2 microglia by lipopolysaccharide triggers an inflammatory reaction in PC12 cell apoptosis through a toll-like receptor 4-dependent pathway

(2014) Xiao-jing Dai et al.   CELL STRESS & CHAPERONES

Lipopolysaccharide treatment arrests the cell cycle of BV-2 microglial cells in G1 phase and protects them from UV light-induced apoptosis

(2014) Yoko S. Kaneko et al.   JOURNAL OF NEURAL TRANSMISSION

Anti-Wrinkle Effect of Magnesium Lithospermate B from Salvia miltiorrhiza BUNGE: Inhibition of MMPs via NF-kB Signaling

(2014) Yu Ri Jung et al.   PLoS One

Magnesium Lithospermate B Protects Neurons from N-Methyl-d-Aspartic Acid Injury and Attenuates Kainic Acid-Induced Neurodegeration in FVB Mice

(2013) Guodong Xiao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Magnesium sulfate provides neuroprotection in lipopolysaccharide-activated primary microglia by inhibiting NF-κB pathway

(2013) Feng Gao et al.   JOURNAL OF SURGICAL RESEARCH

Microglia: Multiple roles in surveillance, circuit shaping, and response to injury

(2013) E. E. Benarroch   NEUROLOGY

Magnesium lithospermate B reduces myocardial ischemia/reperfusion injury in ratsviaregulating the inflammation response

(2013) Wei Quan et al.   PHARMACEUTICAL BIOLOGY

The Classification of Microglial Activation Phenotypes on Neurodegeneration and Regeneration in Alzheimer’s Disease Brain

(2012) Megan M. Varnum et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Suppression of LPS-induced inflammatory responses by inflexanin B in BV2 microglial cells

(2012) Ji-Youn Lim et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Repeated Lipopolysaccharide Stimulation Induces Cellular Senescence in BV2 Cells

(2012) Hong-Mei Yu et al.   NEUROIMMUNOMODULATION

Review: Activation patterns of microglia and their identification in the human brain

(2012) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Inhibitors of Microglial Neurotoxicity: Focus on Natural Products

(2011) Dong Kug Choi et al.   MOLECULES

Chemical genetics of neuroinflammation: natural and synthetic compounds as microglial inhibitors

(2011) Kyoungho Suk et al.   INFLAMMOPHARMACOLOGY

Mg2+ ions reduce microglial and THP-1 cell neurotoxicity by inhibiting Ca2+ entry through purinergic channels

(2010) Moonhee Lee et al.   BRAIN RESEARCH

Anti-inflammatory Activity of Salvianolic Acid B in Microglia Contributes to its Neuroprotective Effect

(2010) Shao-Xia Wang et al.   NEUROCHEMICAL RESEARCH

The Multifaceted Profile of Activated Microglia

(2009) Marina A. Lynch   MOLECULAR NEUROBIOLOGY

The lipopolysaccharide Parkinson’s disease animal model: mechanistic studies and drug discovery

(2008) Garima Dutta et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Induction of myeloid-derived suppressor cells by tumor exosomes

(2008) Xiaoyu Xiang et al.   INTERNATIONAL JOURNAL OF CANCER

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols