P5C as an Interface of Proline Interconvertible Amino Acids and Its Role in Regulation of Cell Survival and Apoptosis
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Title
P5C as an Interface of Proline Interconvertible Amino Acids and Its Role in Regulation of Cell Survival and Apoptosis
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 21, Pages 11763
Publisher
MDPI AG
Online
2021-11-02
DOI
10.3390/ijms222111763
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Note: Only part of the references are listed.- Proline metabolism and transport in retinal health and disease
- (2021) Jianhai Du et al. AMINO ACIDS
- Proline metabolism in cancer
- (2021) Pengyu Geng et al. AMINO ACIDS
- PYCR, a key enzyme in proline metabolism, functions in tumorigenesis
- (2021) Yutong Li et al. AMINO ACIDS
- Isozymes of P5C reductase (PYCR) in human diseases: focus on cancer
- (2021) Chien-An A. Hu AMINO ACIDS
- The Multifaceted Roles of Proline in Cell Behavior
- (2021) Eduardo J. Patriarca et al. Frontiers in Cell and Developmental Biology
- PROLIDASE: A Review from Discovery to its Role in Health and Disease
- (2021) Ireti Eni-Aganga et al. Frontiers in Molecular Biosciences
- Mitochondrial oxidative stress by Lon-PYCR1 maintains an immunosuppressive tumor microenvironment that promotes cancer progression and metastasis
- (2020) Cheng-Liang Kuo et al. CANCER LETTERS
- Proline Metabolism in Tumor Growth and Metastatic Progression
- (2020) Cristina D'Aniello et al. Frontiers in Oncology
- The Janus-like role of proline metabolism in cancer
- (2020) Lynsey Burke et al. Cell Death Discovery
- Kindlin-2 links mechano-environment to proline synthesis and tumor growth
- (2019) Ling Guo et al. Nature Communications
- The Diverse Functions of Non-Essential Amino Acids in Cancer
- (2019) Bo-Hyun Choi et al. Cancers
- The clinical significance of PYCR1 expression in renal cell carcinoma
- (2019) Fu Weijin et al. MEDICINE
- Proline-dependent regulation of collagen metabolism
- (2019) Ewa Karna et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Metabolic pathway analyses identify proline biosynthesis pathway as a promoter of liver tumorigenesis
- (2019) Zhaobing Ding et al. JOURNAL OF HEPATOLOGY
- PYCR1 interference inhibits cell growth and survival via c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathway in hepatocellular cancer
- (2019) Juhua Zhuang et al. Journal of Translational Medicine
- Knockdown of PYCR1 inhibits proliferation, drug resistance and EMT in colorectal cancer cells by regulating STAT3-Mediated p38 MAPK and NF-κB signalling pathway
- (2019) Kun Yan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Proline Cycle As a Potential Cancer Therapy Target
- (2018) John J. Tanner et al. BIOCHEMISTRY
- Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis
- (2018) Kate E.R. Hollinshead et al. Cell Reports
- The Metabolism of Proline as Microenvironmental Stress Substrate
- (2018) James M. Phang et al. JOURNAL OF NUTRITION
- Glutamine Metabolism and Function in Relation to Proline Synthesis and the Safety of Glutamine and Proline Supplementation
- (2018) Malcolm Watford JOURNAL OF NUTRITION
- Pyrroline-5-carboxylate reductase 1 promotes cell proliferation via inhibiting apoptosis in human malignant melanoma
- (2018) Yingyi Ye et al. Cancer Management and Research
- Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1
- (2017) Emily M. Christensen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side
- (2017) Jennifer R. Chao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer
- (2017) Tengyue Zeng et al. MEDICAL ONCOLOGY
- Exogenous proline stimulates type I collagen and HIF-1α expression and the process is attenuated by glutamine in human skin fibroblasts
- (2017) Lukasz Szoka et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass
- (2017) Jessica B. Spinelli et al. SCIENCE
- Pyrroline‑5‑carboxylate reductase 1 promotes proliferation and inhibits apoptosis in non‑small cell lung cancer
- (2017) Feng Cai et al. Oncology Letters
- Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells
- (2017) Ilaria Elia et al. Nature Communications
- Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses
- (2017) James M. Phang ANTIOXIDANTS & REDOX SIGNALING
- Structural Biology of Proline Catabolic Enzymes
- (2017) John J. Tanner ANTIOXIDANTS & REDOX SIGNALING
- 'Nothing of chemistry disappears in biology: the Top 30 damage-prone endogenous metabolites
- (2016) C. Lerma-Ortiz et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Prolidase-proline dehydrogenase/proline oxidase-collagen biosynthesis axis as a potential interface of apoptosis/autophagy
- (2016) Ilona Zareba et al. BIOFACTORS
- Proline Starvation Induces Unresolved ER Stress and Hinders mTORC1-Dependent Tumorigenesis
- (2016) Nisebita Sahu et al. Cell Metabolism
- Proline Oxidase (POX) as A Target for Cancer Therapy
- (2015) Joanna Kononczuk et al. CURRENT DRUG TARGETS
- Proline metabolism and cancer
- (2015) James M. Phang et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Downregulation of pyrroline-5-carboxylate reductase-2 induces the autophagy of melanoma cells via AMPK/mTOR pathway
- (2015) Rongying Ou et al. TUMOR BIOLOGY
- Proline biosynthesis augments tumor cell growth and aerobic glycolysis: involvement of pyridine nucleotides
- (2015) Wei Liu et al. Scientific Reports
- Evolution of proline biosynthesis: enzymology, bioinformatics, genetics, and transcriptional regulation
- (2014) Yosef Fichman et al. BIOLOGICAL REVIEWS
- Proline Oxidase Promotes Tumor Cell Survival in Hypoxic Tumor Microenvironments
- (2012) W. Liu et al. CANCER RESEARCH
- Functional Specialization in Proline Biosynthesis of Melanoma
- (2012) Jessica De Ingeniis et al. PLoS One
- Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC
- (2012) W. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Proline Regulatory Axis and Cancer
- (2012) James Ming Phang et al. Frontiers in Oncology
- The amino acid transporter SNAT2 mediates l-proline-induced differentiation of ES cells
- (2011) Boon Siang Nicholas Tan et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Metabolic Flux and the Regulation of Mammalian Cell Growth
- (2011) Jason W. Locasale et al. Cell Metabolism
- The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
- (2011) Ruoning Wang et al. IMMUNITY
- Proline Metabolism and Microenvironmental Stress
- (2010) James M. Phang et al. Annual Review of Nutrition
- The Collagen Family
- (2010) S. Ricard-Blum Cold Spring Harbor Perspectives in Biology
- The molecular determinants of de novo nucleotide biosynthesis in cancer cells
- (2009) Xuemei Tong et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Regulation and function of proline oxidase under nutrient stress
- (2009) Jui Pandhare et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- p53 Regulation of Metabolic Pathways
- (2009) E. Gottlieb et al. Cold Spring Harbor Perspectives in Biology
- Human Δ1-pyrroline-5-carboxylate synthase: function and regulation
- (2008) C.-A. A. Hu et al. AMINO ACIDS
- The metabolism of proline, a stress substrate, modulates carcinogenic pathways
- (2008) James M. Phang et al. AMINO ACIDS
- Prolidase-dependent regulation of collagen biosynthesis
- (2008) A. Surazynski et al. AMINO ACIDS
- The importance of proline residues in the structure, stability and susceptibility to proteolytic degradation of collagens
- (2008) Stephen M. Krane AMINO ACIDS
- Regulation of glutathione synthesis
- (2008) Shelly C. Lu MOLECULAR ASPECTS OF MEDICINE
- Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers
- (2008) Y Liu et al. ONCOGENE
- JNK signaling in apoptosis
- (2008) D N Dhanasekaran et al. ONCOGENE
- PPARγand Proline Oxidase in Cancer
- (2008) James M. Phang et al. PPAR Research
- Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress
- (2007) Navasona Krishnan et al. FREE RADICAL BIOLOGY AND MEDICINE
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