Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer

Human pyrroline-5-carboxylate reductase (PYCR1) acts on Δ1-piperideine-6-carboxylate generating L-pipecolic acid

(2014) Eduard A. Struys et al.   JOURNAL OF INHERITED METABOLIC DISEASE

DJ-1 cooperates with PYCR1 in cell protection against oxidative stress

(2013) Tatsuki Yasuda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012

(2013) J. Ferlay et al.   EUROPEAN JOURNAL OF CANCER

Mutations in PYCR1 gene in three families with autosomal recessive cutis laxa, type 2

(2013) D.Z. Scherrer et al.   European Journal of Medical Genetics

Cancer Statistics

(2013)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genotype–phenotype spectrum of PYCR1-related autosomal recessive cutis laxa

(2013) Aikaterini Dimopoulou et al.   MOLECULAR GENETICS AND METABOLISM

Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC

(2012) W. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel mutation in PYCR1 causes an autosomal recessive cutis laxa with premature aging features in a family

(2011) Dar-Shong Lin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Defect in proline synthesis: pyrroline-5-carboxylate reductase 1 deficiency leads to a complex clinical phenotype with collagen and elastin abnormalities

(2011) Rita Kretz et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Mutation in Pyrroline-5-Carboxylate Reductase 1 Gene in Families with Cutis Laxa Type 2

(2009) Duane L. Guernsey et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in PYCR1 cause cutis laxa with progeroid features

(2009) Bruno Reversade et al.   NATURE GENETICS

Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress

(2007) Navasona Krishnan et al.   FREE RADICAL BIOLOGY AND MEDICINE