Effects of the Toxic Metals Arsenite and Cadmium on α-Synuclein Aggregation In Vitro and in Cells
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Effects of the Toxic Metals Arsenite and Cadmium on α-Synuclein Aggregation In Vitro and in Cells
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 21, Pages 11455
Publisher
MDPI AG
Online
2021-10-25
DOI
10.3390/ijms222111455
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes
- (2021) Danilo Milardi et al. CHEMICAL REVIEWS
- Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity
- (2021) Stefanie Andersson et al. JOURNAL OF CELL SCIENCE
- Metals associated neurodegeneration in Parkinson’s disease: Insight to physiological, pathological mechanisms and management
- (2021) Khadga Raj et al. NEUROSCIENCE LETTERS
- Mechanisms of amyloid proteins aggregation and their inhibition by antibodies, small molecule inhibitors, nano-particles and nano-bodies
- (2021) Parveen Salahuddin et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils
- (2020) Francesco Simone Ruggeri et al. ACS Nano
- Differential effects of Cu2+ and Fe3+ ions on in vitro amyloid formation of biologically-relevant α-synuclein variants
- (2020) Emma Lorentzon et al. BIOMETALS
- Cryo-EM structure of full-length α-synuclein amyloid fibril with Parkinson’s disease familial A53T mutation
- (2020) Yunpeng Sun et al. CELL RESEARCH
- Parkinson’s disease associated mutation E46K of α-synuclein triggers the formation of a distinct fibril structure
- (2020) Kun Zhao et al. Nature Communications
- Lipid-Chaperone Hypothesis: A Common Molecular Mechanism of Membrane Disruption by Intrinsically Disordered Proteins
- (2020) Michele F. Sciacca et al. ACS Chemical Neuroscience
- Structural Insights into α-Synuclein Fibril Polymorphism: Effects of Parkinson's Disease-Related C-Terminal Truncations
- (2019) Xiaodan Ni et al. JOURNAL OF MOLECULAR BIOLOGY
- α‐synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities
- (2019) Parvez Alam et al. JOURNAL OF NEUROCHEMISTRY
- Regulation of α-synuclein by chaperones in mammalian cells
- (2019) Björn M. Burmann et al. NATURE
- Metal Ion Effects on Aβ and Tau Aggregation
- (2018) Anne Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade
- (2018) Erika N. Cline et al. JOURNAL OF ALZHEIMERS DISEASE
- Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy
- (2018) Yaowang Li et al. CELL RESEARCH
- Phospholipids Critical Micellar Concentrations Trigger Different Mechanisms of Intrinsically Disordered Proteins Interaction with Model Membranes
- (2018) Federica Scollo et al. Journal of Physical Chemistry Letters
- Cadmium Causes Misfolding and Aggregation of Cytosolic Proteins in Yeast
- (2017) Therese Jacobson et al. MOLECULAR AND CELLULAR BIOLOGY
- The Impact of N-terminal Acetylation of α-Synuclein on Phospholipid Membrane Binding and Fibril Structure
- (2016) Aditya Iyer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein
- (2016) Marcus D Tuttle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- From the Cover: Arsenic Induces Accumulation of α-Synuclein: Implications for Synucleinopathies and Neurodegeneration
- (2016) Aram B. Cholanians et al. TOXICOLOGICAL SCIENCES
- Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein
- (2016) Marcus D Tuttle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Copper(I/II), α/β-Synuclein and Amyloid-β: Menage à Trois?
- (2015) Riccardo De Ricco et al. CHEMBIOCHEM
- α-Synuclein Amyloid Fibrils with Two Entwined, Asymmetrically Associated Protofibrils
- (2015) Altaira D. Dearborn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases
- (2015) Miguel Chin-Chan et al. Frontiers in Cellular Neuroscience
- A Revised Picture of the Cu(II)−α-Synuclein Complex: The Role of N-Terminal Acetylation
- (2014) Gina M. Moriarty et al. BIOCHEMISTRY
- A novel α-synuclein mutation A53E associated with atypical multiple system atrophy and Parkinson's disease-type pathology
- (2014) Petra Pasanen et al. NEUROBIOLOGY OF AGING
- Global analysis of protein aggregation in yeast during physiological conditions and arsenite stress
- (2014) S. Ibstedt et al. Biology Open
- Arsenic Binding to Proteins
- (2013) Shengwen Shen et al. CHEMICAL REVIEWS
- The Broad Scope of Health Effects from Chronic Arsenic Exposure: Update on a Worldwide Public Health Problem
- (2013) Marisa F. Naujokas et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Copper(I)-α-Synuclein Interaction: Structural Description of Two Independent and Competing Metal Binding Sites
- (2013) Francesca Camponeschi et al. INORGANIC CHEMISTRY
- Antimicrobial activity of metals: mechanisms, molecular targets and applications
- (2013) Joseph A. Lemire et al. NATURE REVIEWS MICROBIOLOGY
- Cadmium and Its Neurotoxic Effects
- (2013) Bo Wang et al. Oxidative Medicine and Cellular Longevity
- Aggregate Clearance of α-Synuclein inSaccharomyces cerevisiaeDepends More on Autophagosome and Vacuole Function Than on the Proteasome
- (2012) Doris Petroi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Arsenite interferes with protein folding and triggers formation of protein aggregates in yeast
- (2012) T. Jacobson et al. JOURNAL OF CELL SCIENCE
- Structural basis behind the interaction of Zn2+ with the protein α-synuclein and the Aβ peptide: A comparative analysis
- (2012) Ariel A. Valiente-Gabioud et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Metals, oxidative stress and neurodegeneration: A focus on iron, manganese and mercury
- (2012) Marcelo Farina et al. NEUROCHEMISTRY INTERNATIONAL
- Industrial toxicants and Parkinson's disease
- (2012) W. Michael Caudle et al. NEUROTOXICOLOGY
- α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
- (2011) Tim Bartels et al. NATURE
- In vivo demonstration that -synuclein oligomers are toxic
- (2011) B. Winner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Arsenic Exposure Hypothesis for Alzheimer Disease
- (2010) Gordon Gong et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Interaction Between α-Synuclein and Metal Ions, Still Looking for a Role in the Pathogenesis of Parkinson’s Disease
- (2009) Marco Bisaglia et al. NEUROMOLECULAR MEDICINE
- Heavy metal ions are potent inhibitors of protein folding
- (2008) Sandeep K. Sharma et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Arsenic(III) Species Inhibit Oxidative Protein Foldingin Vitro†
- (2008) Danny Ramadan et al. BIOCHEMISTRY
- Phosphorylation, lipid raft interaction and traffic of α-synuclein in a yeast model for Parkinson
- (2008) Piotr Zabrocki et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Calcium(II) selectively induces α-synuclein annular oligomers via interaction with the C-terminal domain
- (2004) Rachel Lowe et al. PROTEIN SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now