Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion

A Drug Screening Pipeline Using 2D and 3D Patient-Derived In Vitro Models for Pre-Clinical Analysis of Therapy Response in Glioblastoma

(2021) Sakthi Lenin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In Vitro Glioblastoma Models: A Journey into the Third Dimension

(2021) Mayra Paolillo et al.   Cancers

Contemporary Mouse Models in Glioma Research

(2021) William H. Hicks et al.   Cells

Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon

(2021) Emilie Darrigues et al.   Frontiers in Oncology

Tracking Gold Nanorods’ Interaction with Large 3D Pancreatic-Stromal Tumor Spheroids by Multimodal Imaging: Fluorescence, Photoacoustic, and Photothermal Microscopies

(2020) Emilie Darrigues et al.   Scientific Reports

Tumor Cell Invasion in Glioblastoma

(2020) Arabel Vollmann-Zwerenz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mimicking tumor hypoxia and tumor-immune interactions employing three-dimensional in vitro models

(2020) Somshuvra Bhattacharya et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Rapid and Efficient Invasion Assay of Glioblastoma in Human Brain Organoids

(2020) Gladiola Goranci-Buzhala et al.   Cell Reports

Radioresistance in Glioblastoma and the Development of Radiosensitizers

(2020) Md Yousuf Ali et al.   Cancers

Multi-Cell Type Glioblastoma Tumor Spheroids for Evaluating Sub-Population-Specific Drug Response

(2020) Hemamylammal Sivakumar et al.   Frontiers in Bioengineering and Biotechnology

Molecular Mechanisms of Treatment Resistance in Glioblastoma

(2020) Alexander Ou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Plasmonic gap-enhanced Raman tag nanorods for imaging 3D pancreatic spheroids using surface-enhanced Raman spectroscopy and darkfield microscopy

(2020) Emilie Darrigues et al.   NANOTECHNOLOGY

Modeling Patient-Derived Glioblastoma with Cerebral Organoids

(2019) Amanda Linkous et al.   Cell Reports

A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity

(2019) Fadi Jacob et al.   CELL

3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment

(2018) Sofia P. Rebelo et al.   BIOMATERIALS

Multidimensional communication in the microenvirons of glioblastoma

(2018) Marike L. Broekman et al.   Nature Reviews Neurology

Role of the NFκB-signaling pathway in cancer

(2018) Longzheng Xia et al.   OncoTargets and Therapy

The comparison genomics analysis with glioblastoma multiforme (GBM) cells under 3D and 2D cell culture conditions

(2018) Liang Ma et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

MMB triazole analogs are potent NF-κB inhibitors and anti-cancer agents against both hematological and solid tumor cells

(2018) Venumadhav Janganati et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Glioblastoma Chemoresistance: The Double Play by Microenvironment and Blood-Brain Barrier

(2018) Martina Da Ros et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Drug Screening of Human GBM Spheroids in Brain Cancer Chip

(2018) Metin Akay et al.   Scientific Reports

Chemoresistance caused by the microenvironment of glioblastoma and the corresponding solutions

(2018) Xin Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells

(2017) Shobanbabu Bommagani et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

INSIDIA: A FIJI Macro Delivering High-Throughput and High-Content Spheroid Invasion Analysis

(2017) Chiara Moriconi et al.   Biotechnology Journal

A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo

(2016) Christopher G. Hubert et al.   CANCER RESEARCH

Small-molecule inhibitors of FGFR, integrins and FAK selectively decrease L1CAM-stimulated glioblastoma cell motility and proliferation

(2016) Hannah J. Anderson et al.   CELLULAR ONCOLOGY

1-Benzyl-2-methyl-3-indolylmethylene barbituric acid derivatives: Anti-cancer agents that target nucleophosmin 1 (NPM1)

(2015) Narsimha Reddy Penthala et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of novel 4,5-disubstituted 2H-1,2,3-triazoles as cis-constrained analogues of combretastatin A-4

(2015) Nikhil R. Madadi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents

(2015) Narsimha Reddy Penthala et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Dimers of Melampomagnolide B Exhibit Potent Anticancer Activity against Hematological and Solid Tumor Cells

(2015) Venumadhav Janganati et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer

(2015) YOSHINORI IMAMURA et al.   ONCOLOGY REPORTS

Synthesis and anti-cancer screening of novel heterocyclic-(2H)-1,2,3-triazoles as potential anti-cancer agents

(2015) Narsimha Reddy Penthala et al.   MedChemComm

Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin

(2015) Nikhil R. Madadi et al.   MedChemComm

Three-Dimensional (3D) Tumor Spheroid Invasion Assay

(2015) Maria Vinci et al.   Jove-Journal of Visualized Experiments

Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing

(2015) Xue Gong et al.   PLoS One

3D cell culture systems modeling tumor growth determinants in cancer target discovery

(2014) Claudio R. Thoma et al.   ADVANCED DRUG DELIVERY REVIEWS

Multilayer Spheroids To Quantify Drug Uptake and Diffusion in 3D

(2014) Toni-Marie Achilli et al.   MOLECULAR PHARMACEUTICS

Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity

(2014) Yao Yao et al.   Nature Communications

Disruption of astrocyte–vascular coupling and the blood–brain barrier by invading glioma cells

(2014) Stacey Watkins et al.   Nature Communications

U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells

(2014) Anja Torsvik et al.   Cancer Medicine

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr

(2011) Carlos A Fedrigo et al.   Radiation Oncology