Tumor-Associated Microglia/Macrophages as a Predictor for Survival in Glioblastoma and Temozolomide-Induced Changes in CXCR2 Signaling with New Resistance Overcoming Strategy by Combination Therapy
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Title
Tumor-Associated Microglia/Macrophages as a Predictor for Survival in Glioblastoma and Temozolomide-Induced Changes in CXCR2 Signaling with New Resistance Overcoming Strategy by Combination Therapy
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 20, Pages 11180
Publisher
MDPI AG
Online
2021-10-18
DOI
10.3390/ijms222011180
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Note: Only part of the references are listed.- The CXCL2/IL8/CXCR2 Pathway Is Relevant for Brain Tumor Malignancy and Endothelial Cell Function
- (2021) Ruth M. Urbantat et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cancer cell heterogeneity & plasticity in glioblastoma and brain tumors
- (2021) Adam Lauko et al. SEMINARS IN CANCER BIOLOGY
- TAMs in Brain Metastasis: Molecular Signatures in Mouse and Man
- (2021) Michael Schulz et al. Frontiers in Immunology
- Establishment and Validation of CyberKnife Irradiation in a Syngeneic Glioblastoma Mouse Model
- (2021) Claudius Jelgersma et al. Cancers
- Antitumor and Radiosensitization Effects of a CXCR2 Inhibitor in Nasopharyngeal Carcinoma
- (2021) Xiaobei Liu et al. Frontiers in Cell and Developmental Biology
- The CXCR2/CXCL2 signalling pathway – An alternative therapeutic approach in high-grade glioma
- (2020) Güliz Acker et al. EUROPEAN JOURNAL OF CANCER
- Revealing and Harnessing Tumour-Associated Microglia/Macrophage Heterogeneity in Glioblastoma
- (2020) Yolanda Pires-Afonso et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Role of Selected Chemokines and Their Receptors in the Development of Gliomas
- (2020) Magdalena Groblewska et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Trends in glioblastoma: outcomes over time and type of intervention: a systematic evidence based analysis
- (2020) Lina Marenco-Hillembrand et al. JOURNAL OF NEURO-ONCOLOGY
- Tumor Development and Angiogenesis in Adult Brain Tumor: Glioblastoma
- (2020) Bhavesh K. Ahir et al. MOLECULAR NEUROBIOLOGY
- Single-Cell Atlas Reveals Complexity of the Immunosuppressive Microenvironment of Initial and Recurrent Glioblastoma
- (2020) Weilun Fu et al. Frontiers in Immunology
- Microglia/macrophages express alternative proangiogenic factors depending on granulocyte content in human glioblastoma
- (2020) Anne Blank et al. JOURNAL OF PATHOLOGY
- Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma
- (2019) Tanwir Hasan et al. Cell Death & Disease
- Challenges to curing primary brain tumours
- (2019) Kenneth Aldape et al. Nature Reviews Clinical Oncology
- Glioblastoma heterogeneity and the tumour microenvironment: implications for preclinical research and development of new treatments
- (2019) Sally L. Perrin et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Intertumoral heterogeneity in patient-specific drug sensitivities in treatment-naïve glioblastoma
- (2019) Erlend Skaga et al. BMC CANCER
- Predictive MGMT status in a homogeneous cohort of IDH wildtype glioblastoma patients
- (2019) Josefine Radke et al. Acta Neuropathologica Communications
- CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2012–2016
- (2019) Quinn T Ostrom et al. NEURO-ONCOLOGY
- A guide to chemokines and their receptors
- (2018) Catherine E. Hughes et al. FEBS Journal
- DMC is not better than TMZ on intracranial anti-glioma effects
- (2018) Lei Shi et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- IL-8 associates with a pro-angiogenic and mesenchymal subtype in glioblastoma
- (2018) Siobhan Conroy et al. Oncotarget
- Interactions between tumor-associated macrophages and tumor cells in glioblastoma: unraveling promising targeted therapies
- (2018) Mony Chenda Morisse et al. Expert Review of Neurotherapeutics
- Challenges in the Treatment of Glioblastoma: Multisystem Mechanisms of Therapeutic Resistance
- (2018) Evan K. Noch et al. World Neurosurgery
- CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma
- (2018) Kartik Angara et al. NEOPLASIA
- Glioblastoma Recurrence Correlates With Increased APE1 and Polarization Toward an Immuno-Suppressive Microenvironment
- (2018) Amanda L. Hudson et al. Frontiers in Oncology
- Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist
- (2017) Haiyan Wang et al. JOURNAL OF NEUROSURGERY
- European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas
- (2017) Michael Weller et al. LANCET ONCOLOGY
- Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma
- (2017) Spyros Darmanis et al. Cell Reports
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Bevacizumab Plus Irinotecan Versus Temozolomide in Newly Diagnosed O6-Methylguanine–DNA Methyltransferase Nonmethylated Glioblastoma: The Randomized GLARIUS Trial
- (2016) Ulrich Herrlinger et al. JOURNAL OF CLINICAL ONCOLOGY
- F8-SIP mediated targeted photodynamic therapy leads to microvascular dysfunction and reduced glioma growth
- (2016) G. Acker et al. JOURNAL OF NEURO-ONCOLOGY
- The role of microglia and macrophages in glioma maintenance and progression
- (2016) Dolores Hambardzumyan et al. NATURE NEUROSCIENCE
- KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment
- (2016) Giuseppina D'Alessandro et al. Oncotarget
- Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors
- (2015) Susan Brandenburg et al. ACTA NEUROPATHOLOGICA
- Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1
- (2015) Frank Szulzewsky et al. PLoS One
- SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1
- (2015) Jaíra Ferreira de Vasconcellos et al. PLoS One
- Correlation of C-X-C chemokine receptor 2 upregulation with poor prognosis and recurrence in human glioma
- (2015) Mei Liu et al. OncoTargets and Therapy
- MGMT testing—the challenges for biomarker-based glioma treatment
- (2014) Wolfgang Wick et al. Nature Reviews Neurology
- Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma
- (2014) Olivier L. Chinot et al. NEW ENGLAND JOURNAL OF MEDICINE
- Molecular imaging coupled to pattern recognition distinguishes response to temozolomide in preclinical glioblastoma
- (2014) Teresa Delgado-Goñi et al. NMR IN BIOMEDICINE
- Blockage of CXCR2 suppresses tumor growth of intrahepatic cholangiocellular carcinoma
- (2014) Hideaki Sueoka et al. SURGERY
- Combined temozolomide and sunitinib treatment leads to better tumour control but increased vascular resistance in O6-methylguanine methyltransferase-methylated gliomas
- (2013) M. Czabanka et al. EUROPEAN JOURNAL OF CANCER
- Vasculogenic mimicry is a prognostic factor for postoperative survival in patients with glioblastoma
- (2013) Shi-yong Wang et al. JOURNAL OF NEURO-ONCOLOGY
- Combination of anti-VEGF therapy and temozolomide in two experimental human glioma models
- (2013) Rachel Grossman et al. JOURNAL OF NEURO-ONCOLOGY
- Impact of extent of resection for recurrent glioblastoma on overall survival
- (2012) Orin Bloch et al. JOURNAL OF NEUROSURGERY
- Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial
- (2012) Annika Malmström et al. LANCET ONCOLOGY
- Combined therapy of temozolomide and ZD6474 (vandetanib) effectively reduces glioblastoma tumor volume through anti-angiogenic and anti-proliferative mechanisms
- (2012) Hyeon Ho Kim Molecular Medicine Reports
- Microvascular biodistribution of L19-SIP in angiogenesis targeting strategies
- (2011) Marcus Czabanka et al. EUROPEAN JOURNAL OF CANCER
- Temozolomide-induced modification of the CXC chemokine network in experimental gliomas
- (2011) Kiss INTERNATIONAL JOURNAL OF ONCOLOGY
- Characteristics of the Alternative Phenotype of Microglia/Macrophages and its Modulation in Experimental Gliomas
- (2011) Konrad Gabrusiewicz et al. PLoS One
- Microglia/macrophages promote glioma progression
- (2010) Haiyan Zhai et al. GLIA
- The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies
- (2009) J. Hol et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The Interleukin-8 Pathway in Cancer
- (2008) D. J.J. Waugh et al. CLINICAL CANCER RESEARCH
- Antiangiogenic therapy in malignant gliomas
- (2008) Andrew D Norden et al. CURRENT OPINION IN ONCOLOGY
- Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas
- (2008) Y Komohara et al. JOURNAL OF PATHOLOGY
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