The CXCL2/IL8/CXCR2 Pathway Is Relevant for Brain Tumor Malignancy and Endothelial Cell Function

The CXCR2/CXCL2 signalling pathway – An alternative therapeutic approach in high-grade glioma

(2020) Güliz Acker et al.   EUROPEAN JOURNAL OF CANCER

Tumor Development and Angiogenesis in Adult Brain Tumor: Glioblastoma

(2020) Bhavesh K. Ahir et al.   MOLECULAR NEUROBIOLOGY

Microglia/macrophages express alternative proangiogenic factors depending on granulocyte content in human glioblastoma

(2020) Anne Blank et al.   JOURNAL OF PATHOLOGY

Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma

(2019) Tanwir Hasan et al.   Cell Death & Disease

CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma

(2018) Kartik Angara et al.   NEOPLASIA

VEGF as a modulator of the innate immune response in glioblastoma

(2017) Kati Turkowski et al.   GLIA

New Directions in Anti-Angiogenic Therapy for Glioblastoma

(2017) Nancy Wang et al.   Neurotherapeutics

Tumor refractoriness to anti-VEGF therapy

(2016) Domenico Ribatti   Oncotarget

Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors

(2015) Susan Brandenburg et al.   ACTA NEUROPATHOLOGICA

SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1

(2015) Jaíra Ferreira de Vasconcellos et al.   PLoS One

Chemokine expression profile of freshly isolated human glioblastoma-associated macrophages/microglia

(2014) KIRSTEN HATTERMANN et al.   ONCOLOGY REPORTS

Molecular mechanisms of the antitumor activity of SB225002: A novel microtubule inhibitor

(2013) Ahmed E. Goda et al.   BIOCHEMICAL PHARMACOLOGY

VEGF-A induces its negative regulator, soluble form of VEGFR-1, by modulating its alternative splicing

(2013) Tetsuya Saito et al.   FEBS LETTERS

CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-β

(2013) J. Jablonska et al.   INTERNATIONAL JOURNAL OF CANCER

Mechanisms of neovascularization and resistance to anti-angiogenic therapies in glioblastoma multiforme

(2013) Yasushi Soda et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Signal Transduction by Vascular Endothelial Growth Factor Receptors

(2013) S. Koch et al.   Cold Spring Harbor Perspectives in Medicine

Anti-Angiogenic Approaches to Malignant Gliomas

(2012) R. Soffietti et al.   CURRENT CANCER DRUG TARGETS

Autocrine VEGF–VEGFR2–Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

(2012) Petra Hamerlik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype

(2012) Y. Piao et al.   NEURO-ONCOLOGY

Glioblastoma Cell-Secreted Interleukin-8 Induces Brain Endothelial Cell Permeability via CXCR2

(2012) Julie Dwyer et al.   PLoS One

Post-radiation increase in VEGF enhances glioma cell motility in vitro

(2012) Whoon Kil et al.   Radiation Oncology

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Signal transduction inhibitors and antiangiogenic therapies for malignant glioma

(2011) Ingo K. Mellinghoff et al.   GLIA

Quantification and cell-to-cell variation of vascular endothelial growth factor receptors

(2010) P.I. Imoukhuede et al.   EXPERIMENTAL CELL RESEARCH

Transcriptional Regulation of an Axonemal Central Apparatus Gene, Sperm-associated Antigen 6, by a SRY-related High Mobility Group Transcription Factor, S-SOX5

(2010) Elizabeth Anne Kiselak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Spheroid-based human endothelial cell microvessel formation in vivo

(2009) Anna M Laib et al.   Nature Protocols

Human Brain Microvascular Endothelial Cells and Umbilical Vein Endothelial Cells Differentially Facilitate Leukocyte Recruitment and Utilize Chemokines for T Cell Migration

(2008) Shumei Man et al.   Clinical & Developmental Immunology

Antiangiogenic therapy in malignant gliomas

(2008) Andrew D Norden et al.   CURRENT OPINION IN ONCOLOGY

The chemokine receptor CXCR2 is differentially regulated on glial cellsin vivo but is not required for successful remyelination after cuprizone-induced demyelination

(2008) Maren Lindner et al.   GLIA