Irisin Protects the Human Placenta from Oxidative Stress and Apoptosis via Activation of the Akt Signaling Pathway

Induction of the PPARγ (Peroxisome Proliferator-Activated Receptor γ)-GCM1 (Glial Cell Missing 1) Syncytialization Axis Reduces sFLT1 (Soluble fms-Like Tyrosine Kinase 1) in the Preeclamptic Placenta

(2021) Brooke Armistead et al.   HYPERTENSION

The Role of NFκB in Healthy and Preeclamptic Placenta: Trophoblasts in the Spotlight

(2020) Brooke Armistead et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The expression and biological function of chemokine CXCL12 and receptor CXCR4/CXCR7 in placenta accreta spectrum disorders

(2020) Yu Long et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Irisin induces trophoblast differentiation via AMPK activation in the human placenta

(2020) Sascha Drewlo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Irisin promotes cementoblast differentiation via p38 MAPK pathway

(2020) Jiaqi Zhu et al.   ORAL DISEASES

Placental regulation of energy homeostasis during human pregnancy

(2020) Brooke Armistead et al.   ENDOCRINOLOGY

Irisin alleviates LPS-induced liver injury and inflammation through inhibition of NLRP3 inflammasome and NF-κB signaling

(2020) Qian Li et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin

(2020) Eun Jeong Park et al.   Frontiers in Cell and Developmental Biology

Preeclampsia

(2019) Sarosh Rana et al.   CIRCULATION RESEARCH

ANXA4 promotes trophoblast invasion via the PI3K/Akt/eNOS pathway in preeclampsia

(2019) Yalan Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Preeclampsia link to gestational hypoxia

(2019) W. Tong et al.   Journal of Developmental Origins of Health and Disease

Human placenta and trophoblast development: key molecular mechanisms and model systems

(2019) Martin Knöfler et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Irisin Prevents Disuse‐Induced Osteocyte Apoptosis

(2019) Giuseppina Storlino et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A glance at the therapeutic potential of irisin against diseases involving inflammation, oxidative stress, and apoptosis: An introductory review

(2018) Hassan Askari et al.   PHARMACOLOGICAL RESEARCH

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

(2018) Hyeonwoo Kim et al.   CELL

Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress

(2018) Jianbin Bi et al.   Redox Biology

Effects and underlying mechanisms of irisin on the proliferation and apoptosis of pancreatic β cells

(2017) Shiwei Liu et al.   PLoS One

Luteolin Inhibits Proliferation and Induces Apoptosis of Human Placental Choriocarcinoma Cells by Blocking the PI3K/AKT Pathway and Regulating Sterol Regulatory Element Binding Protein Activity

(2016) W. Lim et al.   BIOLOGY OF REPRODUCTION

HBxAg suppresses apoptosis of human placental trophoblastic cell lines via activation of the PI3K/Akt pathway

(2016) Weimin Wang et al.   CELL BIOLOGY INTERNATIONAL

Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination

(2016) Jason S. L. Yu et al.   DEVELOPMENT

Alteration of maternal serum irisin levels in gestational diabetes mellitus

(2016) Ulku Mete Ural et al.   Ginekologia Polska

Circulating Antiangiogenic Factors and Myocardial Dysfunction in Hypertensive Disorders of PregnancyNovelty and Significance

(2016) Sajid Shahul et al.   HYPERTENSION

Knockdown of TACC3 inhibits trophoblast cell migration and invasion through the PI3K/Akt signaling pathway

(2016) Xiaojun Zhu et al.   Molecular Medicine Reports

Irisin protects against endothelial injury and ameliorates atherosclerosis in apolipoprotein E-Null diabetic mice

(2015) Junyan Lu et al.   ATHEROSCLEROSIS

The critical role of Akt in cardiovascular function

(2015) Prasanna Abeyrathna et al.   VASCULAR PHARMACOLOGY

Irisin Levels During Pregnancy and Changes Associated With the Development of Preeclampsia

(2014) María F. Garcés et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Oxidative stress and apoptosis in preeclampsia

(2014) Murat Can et al.   TISSUE & CELL

Review of Poly (ADP-ribose) Polymerase (PARP) Mechanisms of Action and Rationale for Targeting in Cancer and Other Diseases

(2013) Julio Morales et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Lysosomal and mitochondrial permeabilization mediates zinc(II) cationic phthalocyanine phototoxicity

(2013) Julieta Marino et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Detecting endogenous SUMO targets in mammalian cells and tissues

(2013) Janina Becker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Irisin-immunoreactivity in neural and non-neural cells of the rodent

(2013) S.L. Dun et al.   NEUROSCIENCE

FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise

(2012) Joo Young Huh et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Evaluation and management of severe preeclampsia before 34 weeks' gestation

(2011) Baha M. Sibai   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Molecular biology of Bax and Bak activation and action

(2010) Dana Westphal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mechanism of Hypoxia-induced GCM1 Degradation

(2009) Meng-Hsiu Chiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hypoxia-Inducible Factor 1/NOR-1 Axis Regulates the Survival Response of Endothelial Cells to Hypoxia

(2009) L. Martorell et al.   MOLECULAR AND CELLULAR BIOLOGY

The PTEN/PI3K/AKT Signalling Pathway in Cancer, Therapeutic Implications

(2008) Amancio Carnero et al.   CURRENT CANCER DRUG TARGETS