Excessive mechanical strain accelerates intervertebral disc degeneration by disrupting intrinsic circadian rhythm

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Mechanobiology of annulus fibrosus and nucleus pulposus cells in intervertebral discs

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The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration

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Herniated Lumbar Intervertebral Disk

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Cyclic tensile stress of human annulus fibrosus cells induces MAPK activation: involvement in proinflammatory gene expression

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Aging and age related stresses: a senescence mechanism of intervertebral disc degeneration

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Environmental Disruption of Circadian Rhythm Predisposes Mice to Osteoarthritis-Like Changes in Knee Joint

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Effects of Cyclic Tensile Strain on Chondrocyte Metabolism: A Systematic Review

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Quantitative T2 Magnetic Resonance Imaging Compared to Morphological Grading of the Early Cervical Intervertebral Disc Degeneration: An Evaluation Approach in Asymptomatic Young Adults

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Cyclic stretch-induced apoptosis in rat annulus fibrosus cells is mediated in part by endoplasmic reticulum stress through nitric oxide production

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Effects of aging and degeneration on the human intervertebral disc during the diurnal cycle: A finite element study

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The response of human anulus fibrosus cells to cyclic tensile strain is frequency-dependent and altered with disc degeneration

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Cell mechanics and the cytoskeleton

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Prolonged Upright Posture Induces Degenerative Changes in Intervertebral Discs of Rat Cervical Spine

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