Temporal Modulation of Differential Alternative Splicing in HaCaT Human Keratinocyte Cell Line Chronically Exposed to Arsenic for up to 28 Wk

Alternative splicing modulates cancer aggressiveness: role in EMT/metastasis and chemoresistance

(2021) Debanwita Roy Burman et al.   MOLECULAR BIOLOGY REPORTS

Alternative polyadenylation: methods, mechanism, function, and role in cancer

(2021) Yi Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Arsenic-induced epigenetic changes in cancer development

(2021) Wesley N. Saintilnord et al.   SEMINARS IN CANCER BIOLOGY

Alternative splicing acts as an independent prognosticator in ovarian carcinoma

(2021) Yan Ouyang et al.   Scientific Reports

Dynamic alteration in miRNA and mRNA expression profiles at different stages of chronic arsenic exposure-induced carcinogenesis in a human cell culture model of skin cancer

(2021) Mayukh Banerjee et al.   ARCHIVES OF TOXICOLOGY

Multilayered regulation of proteome stoichiometry

(2021) Koji Ishikawa   CURRENT GENETICS

Comprehensive analysis of aberrant alternative splicing related to carcinogenesis and prognosis of papillary thyroid cancer

(2021) Xiaobo Zheng et al.   Aging-US

Molecular Mechanisms of Arsenic-Induced Disruption of DNA Repair

(2020) Lok Ming Tam et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Prognostic role of alternative splicing events in head and neck squamous cell carcinoma

(2020) Yanni Ding et al.   Cancer Cell International

Arsenite Exposure Displaces Zinc from ZRANB2 Leading to Altered Splicing

(2020) Mayukh Banerjee et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Arsenic Exposure and Compromised Protein Quality Control

(2020) Lok Ming Tam et al.   CHEMICAL RESEARCH IN TOXICOLOGY

LAMB3 promotes tumour progression through the AKT–FOXO3/4 axis and is transcriptionally regulated by the BRD2/acetylated ELK4 complex in colorectal cancer

(2020) Zhehui Zhu et al.   ONCOGENE

Global threat of arsenic in groundwater

(2020) Joel Podgorski et al.   SCIENCE

Ran GTPase: A Key Player in Tumor Progression and Metastasis

(2020) Zied Boudhraa et al.   Frontiers in Cell and Developmental Biology

Stochastic epigenetic mutations are associated with risk of breast cancer, lung cancer and mature B-cell neoplasms

(2020) Amedeo Gagliardi et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Redox States of Protein Cysteines in Pathways of Protein Turnover and Cytoskeleton Dynamics Are Changed with Aging and Reversed by Slc7a11 Restoration in Mouse Lung Fibroblasts

(2020) Yuxuan Zheng et al.   Oxidative Medicine and Cellular Longevity

The role of alternative splicing in cancer: From oncogenesis to drug resistance

(2020) Rocco Sciarrillo et al.   DRUG RESISTANCE UPDATES

Alternative Splicing: Expanding the Landscape of Cancer Biomarkers and Therapeutics

(2020) Cláudia Bessa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA‑744‑5p is downregulated in colorectal cancer and targets SEPT2 to suppress the malignant phenotype

(2020) Wei Zhang et al.   Molecular Medicine Reports

The Nuclear Pore Complex and mRNA Export in Cancer

(2020) Katherine L. B. Borden   Cancers

Arsenic Exposure and Cancer-Related Proteins in Urine of Indigenous Bolivian Women

(2020) Jessica De Loma et al.   Frontiers in Public Health

The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

(2019) Ying Ge et al.   Nature Communications

The Role of Selenium in Arsenic and Cadmium Toxicity: an Updated Review of Scientific Literature

(2019) Iwona Zwolak   BIOLOGICAL TRACE ELEMENT RESEARCH

g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)

(2019) Uku Raudvere et al.   NUCLEIC ACIDS RESEARCH

Current Knowledge of Germline Genetic Risk Factors for the Development of Non-Medullary Thyroid Cancer

(2019) Kinga Hińcza et al.   Genes

Proteomic characterization of arsenic and cadmium exposure in bladder cells

(2019) Yi‐Ting Chen et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Silencing of long noncoding RNA SRRM2‐AS exerts suppressive effects on angiogenesis in nasopharyngeal carcinoma via activating MYLK‐mediated cGMP‐PKG signaling pathway

(2019) Shaoqing Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Stochastic modelling of multistage carcinogenesis and progression of human lung cancer

(2019) Lingling Li et al.   JOURNAL OF THEORETICAL BIOLOGY

Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution

(2019) Jernej Ule et al.   MOLECULAR CELL

Dynamic Transcriptome-Proteome Correlation Networks Reveal Human Myeloid Differentiation and Neutrophil-Specific Programming

(2019) Arie J. Hoogendijk et al.   Cell Reports

Impact of Phosphorylation on the Mass Spectrometry Quantification of Intact Phosphoproteins

(2018) Zhijie Wu et al.   ANALYTICAL CHEMISTRY

Environmental arsenic exposure: From genetic susceptibility to pathogenesis

(2018) Brenda C. Minatel et al.   ENVIRONMENT INTERNATIONAL

Alternative splicing isoforms in health and disease

(2018) Hyoung Kyu Kim et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Alternative splicing in cancers: From aberrant regulation to new therapeutics

(2018) Xiaowei Song et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Arsenic-Induced Carcinogenesis: The Impact of miRNA Dysregulation

(2018) Ana P Ferragut Cardoso et al.   TOXICOLOGICAL SCIENCES

Differentially Expressed mRNA Targets of Differentially Expressed miRNAs Predict Changes in the TP53 Axis and Carcinogenesis-Related Pathways in Human Keratinocytes Chronically Exposed to Arsenic

(2018) Laila Al-Eryani et al.   TOXICOLOGICAL SCIENCES

Cellular stress alters 3′UTR landscape through alternative polyadenylation and isoform-specific degradation

(2018) Dinghai Zheng et al.   Nature Communications

Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics

(2018) Laura M. Urbanski et al.   Wiley Interdisciplinary Reviews-RNA

Prognostic value and potential function of splicing events in prostate adenocarcinoma

(2018) Zhi-Guang Huang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

miRNA expression profiles of premalignant and malignant arsenic-induced skin lesions

(2018) Laila Al-Eryani et al.   PLoS One

Activated Rho GTPases in Cancer—The Beginning of a New Paradigm

(2018) Pontus Aspenström   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Distinct mechanisms govern the phosphorylation of different SR protein splicing factors

(2018) Yunxin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative 3′ UTRs direct localization of functionally diverse protein isoforms in neuronal compartments

(2018) Camilla Ciolli Mattioli et al.   NUCLEIC ACIDS RESEARCH

Cutaneous Squamous Cell Carcinoma

(2018) Abigail Waldman et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Abnormalities in alternative splicing in diabetes: therapeutic targets

(2017) Zodwa Dlamini et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Wanted DEAD/H or Alive: Helicases Winding Up in Cancers

(2017) Wanpei Cai et al.   JNCI-Journal of the National Cancer Institute

HaCaT Cells as a Reliable In Vitro Differentiation Model to Dissect the Inflammatory/Repair Response of Human Keratinocytes

(2017) Irma Colombo et al.   MEDIATORS OF INFLAMMATION

Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors

(2017) Hong Han et al.   MOLECULAR CELL

The landscape of human mutually exclusive splicing

(2017) Klas Hatje et al.   Molecular Systems Biology

Transient and permanent changes in DNA methylation patterns in inorganic arsenic-mediated epithelial-to-mesenchymal transition

(2017) Meredith Eckstein et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Growing Toolbox for Protein Synthesis Studies

(2017) Shintaro Iwasaki et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression

(2017) Ryuhjin Ahn et al.   Nature Communications

Integration of microRNAome, proteomics and metabolomics to analyze arsenic-induced malignant cell transformation

(2017) Youyou Zhou et al.   Oncotarget

Impact of Alternative Splicing on the Human Proteome

(2017) Yansheng Liu et al.   Cell Reports

XRRA1 Targets ATM/CHK1/2-Mediated DNA Repair in Colorectal Cancer

(2017) Wenjun Wang et al.   Biomed Research International

Wanted DEAD/H or Alive: Helicases Winding Up in Cancers

(2017) Wanpei Cai et al.   JNCI-Journal of the National Cancer Institute

Epigenomic reprogramming in inorganic arsenic-mediated gene expression patterns during carcinogenesis

(2017) Meredith Eckstein et al.   REVIEWS ON ENVIRONMENTAL HEALTH

Alternative splicing regulates distinct subcellular localization of Epithelial splicing regulatory protein 1 (Esrp1) isoforms

(2017) Yueqin Yang et al.   Scientific Reports

Widespread and dynamic translational control of red blood cell development

(2016) Juan R. Alvarez-Dominguez et al.   BLOOD

The ribosome-engaged landscape of alternative splicing

(2016) Robert J Weatheritt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SILAC-based quantitative proteomic analysis reveals widespread molecular alterations in human skin keratinocytes upon chronic arsenic exposure

(2016) Sartaj Ahmad Mir et al.   PROTEOMICS

Low doses of arsenic, via perturbing p53, promotes tumorigenesis

(2016) Suthakar Ganapathy et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The ribosome-engaged landscape of alternative splicing

(2016) Robert J Weatheritt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tunable protein synthesis by transcript isoforms in human cells

(2016) Stephen N Floor et al.   eLife

c-Fos importance for brain development

(2015) Fabiola N. Velazquez et al.   Aging-US

Disruption of Mitotic Progression by Arsenic

(2015) J. Christopher States   BIOLOGICAL TRACE ELEMENT RESEARCH

Inorganic Arsenic-induced cellular transformation is coupled with genome wide changes in chromatin structure, transcriptome and splicing patterns

(2015) Caitlyn Riedmann et al.   BMC GENOMICS

Splicing inhibition of U2AF65leads to alternative exon skipping

(2015) Sunghee Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-coding functions of alternative pre-mRNA splicing in development

(2015) Stefan Mockenhaupt et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Emerging functions of alternative splicing coupled with nonsense-mediated decay

(2014) Fursham M. Hamid et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The mechanistic basis of arsenicosis: Pathogenesis of skin cancer

(2014) Katherine M. Hunt et al.   CANCER LETTERS

Epigenome-wide DNA methylation changes with development of arsenic-induced skin lesions in Bangladesh: A case-control follow-up study

(2014) Wei Jie Seow et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

(2014) Shihao Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prenatal Arsenic Exposure and Shifts in the Newborn Proteome: Interindividual Differences in Tumor Necrosis Factor (TNF)-Responsive Signaling

(2014) Kathryn A. Bailey et al.   TOXICOLOGICAL SCIENCES

Association of low-level arsenic exposure in drinking water with cardiovascular disease: A systematic review and risk assessment

(2014) Joyce S. Tsuji et al.   TOXICOLOGY

Dynamic Integration of Splicing within Gene Regulatory Pathways

(2013) Ulrich Braunschweig et al.   CELL

From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing

(2013) G. K. Marinov et al.   GENOME RESEARCH

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Before It Gets Started: Regulating Translation at the 5′ UTR

(2012) Patricia R. Araujo et al.   COMPARATIVE AND FUNCTIONAL GENOMICS

Function of alternative splicing

(2012) Olga Kelemen et al.   GENE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

(2012) Christine Vogel et al.   NATURE REVIEWS GENETICS

Primer3—new capabilities and interfaces

(2012) Andreas Untergasser et al.   NUCLEIC ACIDS RESEARCH

Selenium interactions and toxicity: a review

(2011) Iwona Zwolak et al.   CELL BIOLOGY AND TOXICOLOGY

Arsenic Toxicology: Translating between Experimental Models and Human Pathology

(2011) J. Christopher States et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

DEGRADE, MOVE, REGROUP: signaling control of splicing proteins

(2011) Florian Heyd et al.   TRENDS IN BIOCHEMICAL SCIENCES

Alternative splicing and evolution: diversification, exon definition and function

(2010) Hadas Keren et al.   NATURE REVIEWS GENETICS

Proteomic analysis of low dose arsenic and ionizing radiation exposure on keratinocytes

(2009) Susanne R. Berglund et al.   PROTEOMICS

Aberrant cytokeratin expression during arsenic-induced acquired malignant phenotype in human HaCaT keratinocytes consistent with epidermal carcinogenesis

(2009) Yang Sun et al.   TOXICOLOGY

Rho GTPases in cancer cell biology

(2008) Francisco M. Vega et al.   FEBS LETTERS

Arsenic-induced malignant transformation of human keratinocytes: Involvement of Nrf2

(2008) Jingbo Pi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Arsenic Exposure and Prevalence of Type 2 Diabetes in US Adults

(2008) Ana Navas-Acien   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Differential Isoform Expression and Interaction with the P32 Regulatory Protein Controls the Subcellular Localization of the Splicing Factor U2AF26

(2008) Florian Heyd et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuation of DNA damage-induced p53 expression by arsenic: A possible mechanism for arsenic co-carcinogenesis

(2007) Shengwen Shen et al.   MOLECULAR CARCINOGENESIS