LncRNA MEG3 suppresses PI3K/AKT/mTOR signalling pathway to enhance autophagy and inhibit inflammation in TNF-α-treated keratinocytes and psoriatic mice

Pathophysiology, Clinical Presentation, and Treatment of Psoriasis

(2020) April W. Armstrong et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Psoriasis Pathogenesis and Treatment

(2019) Adriana Rendon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cellular functions of long noncoding RNAs

(2019) Run-Wen Yao et al.   NATURE CELL BIOLOGY

Autophagy in Skin Diseases

(2019) Yeye Guo et al.   DERMATOLOGY

SOCS5 inhibition induces autophagy to impair metastasis in hepatocellular carcinoma cells via the PI3K/Akt/mTOR pathway

(2019) Mao Zhang et al.   Cell Death & Disease

Anti-inflammation activity of brazilin in TNF-α induced human psoriasis dermatitis skin model

(2019) Da Hee Choi et al.   Applied Biological Chemistry

Long non-coding RNAs in diseases related to inflammation and immunity

(2019) Jiao Chen et al.   Annals of Translational Medicine

Maternally expressed gene 3 (MEG3): A tumor suppressor long non coding RNA

(2019) Soudeh Ghafouri-Fard et al.   BIOMEDICINE & PHARMACOTHERAPY

Autophagy and Inflammation

(2018) Yu Matsuzawa-Ishimoto et al.   Annual Review of Immunology

PI3K/AKT/mTOR activation and autophagy inhibition plays a key role in increased cholesterol during IL-17A mediated inflammatory response in psoriasis

(2018) Pallavi Varshney et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

TNF stimulates IL-6, CXCL8 and VEGF secretion from human keratinocytes via activation of mTOR, inhibited by tetramethoxyluteolin

(2018) Arti B. Patel et al.   EXPERIMENTAL DERMATOLOGY

Comparison of normal versus imiquimod-induced psoriatic skin in mice for penetration of drugs and nanoparticles

(2018) Lin Sun et al.   International Journal of Nanomedicine

Epidermal mTORC1 Signaling Contributes to the Pathogenesis of Psoriasis and Could Serve as a Therapeutic Target

(2018) Claudia Buerger   Frontiers in Immunology

Models in the Research Process of Psoriasis

(2017) Katarzyna Bocheńska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Long non-coding RNAs involved in autophagy regulation

(2017) Lixian Yang et al.   Cell Death & Disease

Network analysis of psoriasis reveals biological pathways and roles for coding and long non-coding RNAs

(2016) Richard Ahn et al.   BMC GENOMICS

The Inflammatory Response in Psoriasis: a Comprehensive Review

(2016) Yaxiong Deng et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer

(2016) Yiwen Fang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy

(2016) Kamlesh Pawar et al.   Scientific Reports

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

(2014) David Heras-Sandoval et al.   CELLULAR SIGNALLING

Targeting PI3K/Akt/mTOR Signaling in Cancer

(2014) Camillo Porta et al.   Frontiers in Oncology

Autophagy and human diseases

(2013) Peidu Jiang et al.   CELL RESEARCH

Long Noncoding RNAs: Past, Present, and Future

(2013) J. T. Y. Kung et al.   GENETICS

mTOR signaling cascade in psoriatic disease: Double kinase mtor inhibitor a novel therapeutic target

(2013) SibaR Raychaudhuri et al.   INDIAN JOURNAL OF DERMATOLOGY

Autophagy and bacterial infectious diseases

(2012) Jae-Min Yuk et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Psoriasis

(2009) Frank O. Nestle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL