The Inflammatory Response in Psoriasis: a Comprehensive Review

GITR+ regulatory T cells in the treatment of autoimmune diseases

(2015) Maria Grazia Petrillo et al.   AUTOIMMUNITY REVIEWS

Emerging role of long noncoding RNAs in autoimmune diseases

(2015) Guo-Cui Wu et al.   AUTOIMMUNITY REVIEWS

Humoral autoimmunity: A failure of regulatory T cells?

(2015) Tessa Dhaeze et al.   AUTOIMMUNITY REVIEWS

Treatment of Eczema: Corticosteroids and Beyond

(2015) Melanie Chong et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Genetics of Psoriasis

(2015) Satveer K. Mahil et al.   DERMATOLOGIC CLINICS

Therapeutic and immunomodulatory effects of glucosamine in combination with low-dose cyclosporine A in a murine model of imiquimod-induced psoriasis

(2015) Chang-Hyun Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Laser capture microdissection followed by next-generation sequencing identifies disease-related microRNAs in psoriatic skin that reflect systemic microRNA changes in psoriasis

(2015) Marianne B. Løvendorf et al.   EXPERIMENTAL DERMATOLOGY

Secukinumab (AIN457) for the treatment of psoriasis

(2015) Anna López-Ferrer et al.   Expert Review of Clinical Immunology

Human mast cells are major IL-22 producers in patients with psoriasis and atopic dermatitis

(2015) Shunya Mashiko et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells

(2015) Charles J.M. Bell et al.   JOURNAL OF AUTOIMMUNITY

Regulatory dendritic cells in autoimmunity: A comprehensive review

(2015) Juan Liu et al.   JOURNAL OF AUTOIMMUNITY

The interleukin-15 system suppresses T cell-mediated autoimmunity by regulating negative selection and nTH17 cell homeostasis in the thymus

(2015) Mau-Sheng Hou et al.   JOURNAL OF AUTOIMMUNITY

A T cell extrinsic mechanism by which IL-2 dampens Th17 differentiation

(2015) Ana C. Anderson et al.   JOURNAL OF AUTOIMMUNITY

The genetics of human autoimmune disease: A perspective on progress in the field and future directions

(2015) Michael F. Seldin   JOURNAL OF AUTOIMMUNITY

Inflammasomes and human autoimmunity: A comprehensive review

(2015) Chin-An Yang et al.   JOURNAL OF AUTOIMMUNITY

Interleukin-17 and innate immunity in infections and chronic inflammation

(2015) Natasa Isailovic et al.   JOURNAL OF AUTOIMMUNITY

Thymic B cells promote thymus-derived regulatory T cell development and proliferation

(2015) Fang-Ting Lu et al.   JOURNAL OF AUTOIMMUNITY

TNF inhibitors directly target Th17 cells via attenuation of autonomous TNF/TNFR2 signalling in psoriasis

(2015) Takeo Shiga et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

IL-4 Downregulates IL-1β and IL-6 and Induces GATA3 in Psoriatic Epidermal Cells: Route of Action of a Th2 Cytokine

(2015) Armanda J. Onderdijk et al.   JOURNAL OF IMMUNOLOGY

Efficacy and safety of etanercept and adalimumab with and without a loading dose for psoriasis: A systematic review

(2015) Kathleen E. Gilbert et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Psoriasis

(2015) Wolf-Henning Boehncke et al.   LANCET

Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial

(2015) Hervé Bachelez et al.   LANCET

Genetic and epigenetic basis of psoriasis pathogenesis

(2015) Aditi Chandra et al.   MOLECULAR IMMUNOLOGY

NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis

(2015) Sha Yan et al.   Nature Communications

Risk of Serious Infection With Biologic and Systemic Treatment of Psoriasis

(2015) Robert E. Kalb et al.   JAMA Dermatology

Patterns of Medication Utilization and Costs Associated with the Use of Etanercept, Adalimumab, and Ustekinumab in the Management of Moderate-to-Severe Psoriasis

(2015) Steven R. Feldman et al.   Journal of Managed Care & Specialty Pharmacy

Novel Epigenetic Changes Unveiled by Monozygotic Twins Discordant for Smoking Habits

(2015) Alessandra Allione et al.   PLoS One

Immunology of Psoriasis

(2014) Michelle A. Lowes et al.   Annual Review of Immunology

Characterization and profiling of immunomodulatory genes in resident mesenchymal stem cells reflect the Th1-Th17/Th2 imbalance of psoriasis

(2014) A. Campanati et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Diagnosis and classification of psoriasis

(2014) Smriti K. Raychaudhuri et al.   AUTOIMMUNITY REVIEWS

Unmet Needs in Autoimmunity and Potential New Tools

(2014) Qianjin Lu   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

NOS2 and CCL27: clinical implications for psoriasis and eczema diagnosis and management

(2014) Natalie Garzorz et al.   Expert Review of Clinical Immunology

Autoimmunity: From black water fever to regulatory function

(2014) Christopher Chang   JOURNAL OF AUTOIMMUNITY

Polymyalgia rheumatica – Diagnosis and classification

(2014) Gideon Nesher   JOURNAL OF AUTOIMMUNITY

Analysis of Th1/Th2 response pattern for erythrodermic psoriasis

(2014) Ping Zhang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Induction of IL-17+ T Cell Trafficking and Development by IFN- : Mechanism and Pathological Relevance in Psoriasis

(2014) I. Kryczek et al.   JOURNAL OF IMMUNOLOGY

IL-19 Is a Component of the Pathogenetic IL-23/IL-17 Cascade in Psoriasis

(2014) Ellen Witte et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CARD14 Expression in Dermal Endothelial Cells in Psoriasis

(2014) Jamie L. Harden et al.   PLoS One

Safety and Tolerability of Tumor Necrosis Factor-α Inhibitors in Psoriasis: A Narrative Review

(2013) Ashley L. Semble et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Cost Effectiveness of Biologic Therapies for Plaque Psoriasis

(2013) Christine S. Ahn et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

The new era for the treatment of psoriasis and psoriatic arthritis: Perspectives and validated strategies

(2013) Lucia Novelli et al.   AUTOIMMUNITY REVIEWS

Up-regulation of microRNA-210 induces immune dysfunction via targeting FOXP3 in CD4+ T cells of psoriasis vulgaris

(2013) Ming Zhao et al.   CLINICAL IMMUNOLOGY

Novel Mechanisms of Action of the Biologicals in Rheumatic Diseases

(2013) Cecilia Beatrice Chighizola et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Advances on regulatory T cells from the 15th International Congress of Immunology

(2013) Shawn DP Ellis et al.   Expert Review of Clinical Immunology

Human dendritic cell subsets

(2013) Matthew Collin et al.   IMMUNOLOGY

Dermal γδ T cells — A new player in the pathogenesis of psoriasis

(2013) Yihua Cai et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

DNA methylation of dermal MSCs in psoriasis: Identification of epigenetically dysregulated genes

(2013) Ruixia Hou et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Cardiovascular disease event rates in patients with severe psoriasis treated with systemic anti-inflammatory drugs: a Danish real-world cohort study

(2013) O. Ahlehoff et al.   JOURNAL OF INTERNAL MEDICINE

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

Involvement of IL-9 in Th17-Associated Inflammation and Angiogenesis of Psoriasis

(2013) Tej Pratap Singh et al.   PLoS One

Oral apremilast in the treatment of active psoriatic arthritis: Results of a multicenter, randomized, double-blind, placebo-controlled study

(2012) Georg Schett et al.   ARTHRITIS AND RHEUMATISM

The characteristics of genome-wide DNA methylation in naïve CD4+ T cells of patients with psoriasis or atopic dermatitis

(2012) Jihye Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A randomized, double-blind, placebo-controlled study to evaluate the addition of methotrexate to etanercept in patients with moderate to severe plaque psoriasis

(2012) A.B. Gottlieb et al.   BRITISH JOURNAL OF DERMATOLOGY

New insights of T cells in the pathogenesis of psoriasis

(2012) Yihua Cai et al.   Cellular & Molecular Immunology

The Antimicrobial Protein REG3A Regulates Keratinocyte Proliferation and Differentiation after Skin Injury

(2012) Yuping Lai et al.   IMMUNITY

Effects ofMalasseziayeasts on serum Th1 and Th2 cytokines in patients with guttate psoriasis

(2012) Kenan Aydogan et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

S3 - Guidelines on the treatment of psoriasis vulgaris (English version). Update

(2012) Alexander Nast et al.   JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT

IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis

(2012) James G. Krueger et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice

(2012) Stanislav Pantelyushin et al.   JOURNAL OF CLINICAL INVESTIGATION

NF-κB: An essential transcription factor in psoriasis

(2012) A.M. Goldminz et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Etanercept provides an effective, safe and flexible short- and long-term treatment regimen for moderate-to-severe psoriasis: a systematic review of current evidence

(2012) Robert Strohal et al.   JOURNAL OF DERMATOLOGICAL TREATMENT

A Single Intradermal Injection of IFN-γ Induces an Inflammatory State in Both Non-Lesional Psoriatic and Healthy Skin

(2012) Leanne M. Johnson-Huang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

(2012) Lam C Tsoi et al.   NATURE GENETICS

Hiding under the skin: Interleukin-17–producing γδ T cells go under the skin?

(2012) Burkhard Becher et al.   NATURE MEDICINE

Proteins derived from neutrophil extracellular traps may serve as self-antigens and mediate organ damage in autoimmune diseases

(2012) Jason S. Knight et al.   Frontiers in Immunology

IFN-γ, IL-17 and TGF-β involvement in shaping the tumor microenvironment: The significance of modulating such cytokines in treating malignant solid tumors

(2011) Heba A Alshaker et al.   Cancer Cell International

The IL-23 axis in Salmonella gastroenteritis

(2011) Ivan Godinez et al.   CELLULAR MICROBIOLOGY

Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation

(2011) Yihua Cai et al.   IMMUNITY

NK Cells and Psoriasis

(2011) Sinéad Dunphy et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Alternative splicing of CARMA2/CARD14 transcripts generates protein variants with differential effect on NF-κB activation and endoplasmic reticulum stress-induced cell death

(2011) Ivan Scudiero et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Epidermal CCR6 + γδ T Cells Are Major Producers of IL-22 and IL-17 in a Murine Model of Psoriasiform Dermatitis

(2011) Tomotaka Mabuchi et al.   JOURNAL OF IMMUNOLOGY

Identification of a Novel Proinflammatory Human Skin-Homing V 9V 2 T Cell Subset with a Potential Role in Psoriasis

(2011) U. Laggner et al.   JOURNAL OF IMMUNOLOGY

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

(2011) Vladimir Ramirez-Carrozzi et al.   NATURE IMMUNOLOGY

The IL23R R381Q Gene Variant Protects against Immune-Mediated Diseases by Impairing IL-23-Induced Th17 Effector Response in Humans

(2011) Paola Di Meglio et al.   PLoS One

Involvement of IL-17F via the induction of IL-6 in psoriasis

(2010) Sawa Fujishima et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Clinical development of onercept, a tumor necrosis factor binding protein, in psoriasis

(2010) Kim Papp   CURRENT MEDICAL RESEARCH AND OPINION

MicroRNAs and potential target interactions in psoriasis

(2010) John R. Zibert et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Abnormal DNA methylation in skin lesions and PBMCs of patients with psoriasis vulgaris

(2010) Peng Zhang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

The IFN- -Dependent Suppressor of Cytokine Signaling 1 Promoter Activity Is Positively Regulated by IFN Regulatory Factor-1 and Sp1 but Repressed by Growth Factor Independence-1b and Kruppel-Like Factor-4, and It Is Dysregulated in Psoriatic Keratinocytes

(2010) S. Madonna et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: A Critical Functional Role for IL-23 in Psoriasis

(2010) G. Tonel et al.   JOURNAL OF IMMUNOLOGY

A Subpopulation of CD163-Positive Macrophages Is Classically Activated in Psoriasis

(2010) Judilyn Fuentes-Duculan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

(2010) Ju-Hyun Park et al.   NATURE GENETICS

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

(2010) Eva Ellinghaus et al.   NATURE GENETICS

Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis

(2010) Ulrike Hüffmeier et al.   NATURE GENETICS

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

(2010) Amy Strange et al.   NATURE GENETICS

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

(2010) W. Hueber et al.   Science Translational Medicine

Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin

(2009) C. Johansen et al.   BRITISH JOURNAL OF DERMATOLOGY

New biologics for psoriasis and psoriatic arthritis

(2009) Mariya Rozenblit et al.   Dermatologic Therapy

Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling

(2009) Yeonseok Chung et al.   IMMUNITY

Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals

(2009) Bruno Martin et al.   IMMUNITY

Increased expression of IL-12p70 and IL-23 by multiple dendritic cell and macrophage subsets in plaque psoriasis

(2009) Nikhil Yawalkar et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis

(2009) L. van der Fits et al.   JOURNAL OF IMMUNOLOGY

Th17 Cytokines Stimulate CCL20 Expression in Keratinocytes In Vitro and In Vivo: Implications for Psoriasis Pathogenesis

(2009) Erin G. Harper et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular Dissection of Psoriasis: Integrating Genetics and Biology

(2009) James T. Elder et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21

(2009) Xue-Jun Zhang et al.   NATURE GENETICS

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

(2009) Rafael de Cid et al.   NATURE GENETICS

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

(2009) Jian-Wen Han et al.   NATURE GENETICS

Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

(2009) Rajan P Nair et al.   NATURE GENETICS

IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells

(2009) W. Elyaman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion

(2008) C. Chizzolini et al.   BLOOD

The methylation pattern of p16INK4agene promoter in psoriatic epidermis and its clinical significance

(2008) M. Chen et al.   BRITISH JOURNAL OF DERMATOLOGY

Novel primary immunodeficiencies revealed by the investigation of paediatric infectious diseases

(2008) Jacinta Bustamante et al.   CURRENT OPINION IN IMMUNOLOGY

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

TGF-β–dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis

(2008) Honglin Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Polymorphisms of the IL12B and IL23R Genes Are Associated with Psoriasis

(2008) Rajan P. Nair et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Resident and “Inflammatory” Dendritic Cells in Human Skin

(2008) Lisa C. Zaba et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY