Charcot–Leyden crystals and other protein crystals driving type 2 immunity and allergy

Charcot-Leyden crystal protein/galectin-10 interacts with cationic ribonucleases and is required for eosinophil granulogenesis

(2020) Milica M. Grozdanovic et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Kinetic studies of galectin‐10 release from eosinophils exposed to proliferating T cells

(2020) Christine Lingblom et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

A substantial neutrophilic inflammation as regular part of severe type 2 chronic rhinosinusitis with nasal polyps

(2020) Tim Delemarre et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Natural polymorphism of Ym1 regulates pneumonitis through alternative activation of macrophages

(2020) Wenhua Zhu et al.   Science Advances

Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma

(2019) Marrah E Lachowicz-Scroggins et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Protein crystallization promotes type 2 immunity and is reversible by antibody treatment

(2019) Emma K. Persson et al.   SCIENCE

Charcot–Leyden crystal protein/galectin-10 is a surrogate biomarker of eosinophilic airway inflammation in asthma

(2019) Sharmilee M Nyenhuis et al.   Biomarkers in Medicine

Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis

(2019) Elien Gevaert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Chitinase-like proteins as regulators of innate immunity and tissue repair: helpful lessons for asthma?

(2018) Tara E. Sutherland   BIOCHEMICAL SOCIETY TRANSACTIONS

Protein crystallization in living cells

(2018) Robert Schönherr et al.   BIOLOGICAL CHEMISTRY

Charcot–Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1β Inflammation in Human Macrophages

(2018) Juan Francisco Rodríguez-Alcázar et al.   JOURNAL OF IMMUNOLOGY

Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection

(2018) Tara E. Sutherland et al.   PLoS Pathogens

Eosinophil Extracellular Traps and Inflammatory Pathologies—Untangling the Web!

(2018) Manali Mukherjee et al.   Frontiers in Immunology

Charcot–Leyden crystals: do they exist in veterinary species? A case report and literature review

(2017) Eunju Choi et al.   JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION

Eosinophil ETosis and DNA Traps: a New Look at Eosinophilic Inflammation

(2016) Shigeharu Ueki et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung

(2016) Ismé M. de Kleer et al.   IMMUNITY

The Peripheral Blood Eosinophil Proteome

(2016) Emily M. Wilkerson et al.   JOURNAL OF PROTEOME RESEARCH

Diabetic Wounds Exhibit Decreased Ym1 and Arginase Expression with Increased Expression of IL-17 and IL-20

(2016) Phillip J. Finley et al.   Advances in Wound Care

IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation

(2015) Ben Roediger et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Therapeutic response to HMGB1-R3V6-conjugated Ym1/Ym2 siRNA complex in ovalbumin-induced murine asthma

(2015) Jahyun Gu et al.   JOURNAL OF CONTROLLED RELEASE

Uptake of Neutrophil-Derived Ym1 Protein Distinguishes Wound Macrophages in the Absence of Interleukin-4 Signaling in Murine Wound Healing

(2014) Itamar Goren et al.   AMERICAN JOURNAL OF PATHOLOGY

Establishment of a quantitative PCR system for discriminating chitinase-like proteins: catalytically inactive breast regression protein-39 and Ym1 are constitutive genes in mouse lung

(2014) Misa Ohno et al.   BMC MOLECULAR BIOLOGY

Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage

(2014) Tara E Sutherland et al.   NATURE IMMUNOLOGY

M2 macrophage polarisation is associated with alveolar formation during postnatal lung development

(2013) Christina V Jones et al.   RESPIRATORY RESEARCH

Galectin-10, a Potential Biomarker of Eosinophilic Airway Inflammation

(2012) Justin C. Chua et al.   PLoS One

Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo

(2012) P. C. Cook et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ym1/2 Promotes Th2 Cytokine Expression by Inhibiting 12/15(S)-Lipoxygenase: Identification of a Novel Pathway for Regulating Allergic Inflammation

(2009) Y. Cai et al.   JOURNAL OF IMMUNOLOGY

Ym1 and Ym2 expression in a mouse model exposed to diesel exhaust particles

(2008) Hyun-Mi Song et al.   ENVIRONMENTAL TOXICOLOGY

Proteome Analysis of Chronically Inflamed Lungs in a Mouse Chronic Asthma Model

(2008) W.S. Fred Wong et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY