Natural polymorphism of Ym1 regulates pneumonitis through alternative activation of macrophages

Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation

(2019) Sarah C. Starossom et al.   Nature Communications

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases

(2019) Marzena Mazur et al.   JOURNAL OF MEDICINAL CHEMISTRY

Association of NOX2 subunits genetic variants with autoimmune diseases

(2018) Jianghong Zhong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chronic Active Arthritis Driven by Macrophages Without Involvement of T Cells

(2018) Cecilia Hagert et al.   Arthritis & Rheumatology

Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection

(2018) Tara E. Sutherland et al.   PLoS Pathogens

Characterisation of asthma subgroups associated with circulating YKL-40 levels

(2017) Jose L. Gomez et al.   EUROPEAN RESPIRATORY JOURNAL

A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases

(2017) Jian Zhao et al.   NATURE GENETICS

Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death

(2017) Neta Shlezinger et al.   SCIENCE

Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease

(2016) Anna J. James et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Smoke and autoimmunity: The fire behind the disease

(2016) Carlo Perricone et al.   AUTOIMMUNITY REVIEWS

Rheumatoid arthritis: identifying and characterising polymorphisms using rat models

(2016) Anthony C. Y. Yau et al.   Disease Models & Mechanisms

Molecular control of activation and priming in macrophages

(2016) Christopher K Glass et al.   NATURE IMMUNOLOGY

Genetic variation in chitinase 3-like 1 (CHI3L1) contributes to asthma severity and airway expression of YKL-40

(2015) Jose L. Gomez et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites

(2015) Lark Kyun Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization

(2015) Geming Lu et al.   Nature Communications

Tryptophan catabolism is unaffected in chronic granulomatous disease

(2014) Ghassan J. Maghzal et al.   NATURE

Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage

(2014) Tara E Sutherland et al.   NATURE IMMUNOLOGY

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

(2014) Christine Schauer et al.   NATURE MEDICINE

Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice

(2014) I. Khmaladze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Reprograming in Macrophage Polarization

(2014) Silvia Galván-Peña et al.   Frontiers in Immunology

Enhancement of Antibody-Induced Arthritis via Toll-Like Receptor 2 Stimulation Is Regulated by Granulocyte Reactive Oxygen Species

(2012) Tiina Kelkka et al.   AMERICAN JOURNAL OF PATHOLOGY

High-resolution mapping of a complex disease, a model for rheumatoid arthritis, using heterogeneous stock mice

(2011) Emma Ahlqvist et al.   HUMAN MOLECULAR GENETICS

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

(2009) Denis Bedoret et al.   JOURNAL OF CLINICAL INVESTIGATION

Ym1/2 Promotes Th2 Cytokine Expression by Inhibiting 12/15(S)-Lipoxygenase: Identification of a Novel Pathway for Regulating Allergic Inflammation

(2009) Y. Cai et al.   JOURNAL OF IMMUNOLOGY

Adipocyte-Derived Th2 Cytokines and Myeloid PPARδ Regulate Macrophage Polarization and Insulin Sensitivity

(2008) Kihwa Kang et al.   Cell Metabolism

The “Classical” Ovalbumin Challenge Model of Asthma in Mice

(2008) Rakesh Kumar et al.   CURRENT DRUG TARGETS