Single-cell RNA analysis reveals the potential risk of organ-specific cell types vulnerable to SARS-CoV-2 infections

rs1990622 variant associates with Alzheimer’s disease and regulates TMEM106B expression in human brain tissues

(2021) Yang Hu et al.   BMC Medicine

Functional alterations caused by mutations reflect evolutionary trends of SARS-CoV-2

(2021) Liang Cheng et al.   BRIEFINGS IN BIOINFORMATICS

Inference and analysis of cell-cell communication using CellChat

(2021) Suoqin Jin et al.   Nature Communications

Distinct uptake, amplification, and release of SARS-CoV-2 by M1 and M2 alveolar macrophages

(2021) Jiadi Lv et al.   Cell Discovery

Integration of Multiple-Omics Data to Analyze the Population-Specific Differences for Coronary Artery Disease

(2021) Yang Hu et al.   Computational and Mathematical Methods in Medicine

Essential role of M1 macrophages in blocking cytokine storm and pathology associated with murine HSV-1 infection

(2021) Ujjaldeep Jaggi et al.   PLoS Pathogens

GeneSwitches: Ordering gene-expression and functional events in single-cell experiments

(2020) Elaine Y Cao et al.   BIOINFORMATICS

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function

(2020) Li Wang et al.   NATURE CELL BIOLOGY

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

(2020) Lirong Zou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Single-cell RNA sequencing of human kidney

(2020) Jinling Liao et al.   Scientific Data

Identifying cell types to interpret scRNA-seq data: how, why and more possibilities

(2020) Ziwei Wang et al.   Briefings in Functional Genomics

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

(2020) Jun Lan et al.   NATURE

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

(2020) Waradon Sungnak et al.   NATURE MEDICINE

Severe Covid-19

(2020) David A. Berlin et al.   NEW ENGLAND JOURNAL OF MEDICINE

SARS-CoV-2 productively infects human gut enterocytes

(2020) Mart M. Lamers et al.   SCIENCE

Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)

(2020) W. Joost Wiersinga et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Repurpose Open Data to Discover Therapeutics for COVID-19 Using Deep Learning

(2020) Xiangxiang Zeng et al.   JOURNAL OF PROTEOME RESEARCH

Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

(2020) Yujun Tang et al.   Frontiers in Immunology

The COVID-19 Cytokine Storm; What We Know So Far

(2020) Dina Ragab et al.   Frontiers in Immunology

Unveiling COVID-19-associated organ-specific cell types and cell-specific pathway cascade

(2020) Ashmita Dey et al.   BRIEFINGS IN BIOINFORMATICS

Databases for the targeted COVID‐19 therapeutics

(2020) Yunxia Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

(2020) Ludovico Cantuti-Castelvetri et al.   SCIENCE

Elucidation of Biological Networks across Complex Diseases Using Single-Cell Omics

(2020) Yang Li et al.   TRENDS IN GENETICS

Furin: A Potential Therapeutic Target for COVID-19

(2020) Canrong Wu et al.   iScience

Cytokine Storm

(2020) David C. Fajgenbaum et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comprehensive analysis of TCR repertoire in COVID-19 using single cell sequencing

(2020) Pingping Wang et al.   GENOMICS

RMDB: An integrated database of single-cytosine-resolution DNA methylation in Oryza sativa

(2019) Tiansheng Zhu et al.   Current Bioinformatics

Computational methods for identifying the critical nodes in biological networks

(2019) Xiangrong Liu et al.   BRIEFINGS IN BIOINFORMATICS

Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis

(2019) Christina Morse et al.   EUROPEAN RESPIRATORY JOURNAL

QUBIC2: a novel and robust biclustering algorithm for analyses and interpretation of large-scale RNA-Seq data

(2019) Juan Xie et al.   BIOINFORMATICS

Single-Cell Transcriptomic Map of the Human and Mouse Bladders

(2019) Zhenyuan Yu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Clustering of Single-cell RNA-seq Data by Unsupervised Learning Methods

(2018) Xiaoshu Zhu et al.   Current Bioinformatics

Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations

(2018) Sonya A. MacParland et al.   Nature Communications

Meta-path methods for prioritizing candidate disease miRNAs

(2017) Xuan Zhang et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Single-cell mRNA quantification and differential analysis with Census

(2017) Xiaojie Qiu et al.   NATURE METHODS

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Fast unfolding of communities in large networks

(2008) Vincent D Blondel et al.   JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT