Essential role of M1 macrophages in blocking cytokine storm and pathology associated with murine HSV-1 infection

CD8+ T cells in the central nervous system of mice with herpes simplex infection are highly activated and express high levels of CCR5 and CXCR3

(2021) Liza Lind et al.   JOURNAL OF NEUROVIROLOGY

Bone Marrow-Derived and Elicited Peritoneal Macrophages Are Not Created Equal: The Questions Asked Dictate the Cell Type Used

(2020) Cheryl M. Zajd et al.   Frontiers in Immunology

Establishment and Maintenance of the Macrophage Niche

(2020) Martin Guilliams et al.   IMMUNITY

Increased phagocytosis in the presence of enhanced M2-like macrophage responses correlates with increased primary and latent HSV-1 infection

(2020) Ujjaldeep Jaggi et al.   PLoS Pathogens

β1 and β2 integrins: central players in regulating vascular permeability and leukocyte recruitment during acute inflammation

(2020) Ziwei Ou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

COVID 19: in the eye of the cytokine storm

(2020) Giovanna Liuzzo et al.   EUROPEAN HEART JOURNAL

In-Depth Characterization of Monocyte-Derived Macrophages using a Mass Cytometry-Based Phagocytosis Assay

(2019) Daniel Schulz et al.   Scientific Reports

Roles of type 1, 2 and 3 innate lymphoid cells in HSV-1 infection in vitro and in vivo

(2019) Satoshi Hirose et al.   JOURNAL OF VIROLOGY

CCR2+ migratory macrophages with M1 status are the early-responders in the cornea of HSV-1 infected mice

(2019) Dhong Hyun Lee et al.   PLoS One

Expression of Murine CD80 by Herpes Simplex Virus 1 in Place of Latency-Associated Transcript (LAT) Can Compensate for Latency Reactivation and Anti-apoptotic Functions of LAT

(2019) Ujjaldeep Jaggi et al.   JOURNAL OF VIROLOGY

On the role of retinoic acid in virus induced inflammatory response in cornea

(2018) Ujjaldeep Jaggi et al.   MICROBES AND INFECTION

Deficiency of GATA3-Positive Macrophages Improves Cardiac Function Following Myocardial Infarction or Pressure Overload Hypertrophy

(2018) Mingjie Yang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Pathological processes activated by herpes simplex virus-1 (HSV-1) infection in the cornea

(2018) Lulia Koujah et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Role of Herpes Simplex Virus Type 1 (HSV-1) Glycoprotein K (gK) Pathogenic CD8+ T Cells in Exacerbation of Eye Disease

(2018) Ujjaldeep Jaggi et al.   Frontiers in Immunology

Cytokine storm and sepsis disease pathogenesis

(2017) Benjamin G. Chousterman et al.   Seminars in Immunopathology

Dendritic cells, macrophages, NK and CD8+ T lymphocytes play pivotal roles in controlling HSV-1 in the trigeminal ganglia by producing IL1-beta, iNOS and granzyme B

(2017) Natália Lucinda et al.   Virology Journal

Suppression of IL-12p70 formation by IL-2 or following macrophage depletion causes T-cell autoreactivity leading to CNS demyelination in HSV-1-infected mice

(2017) Dhong Hyun Lee et al.   PLoS Pathogens

Neutrophils are dispensable in the modulation of T cell immunity against cutaneous HSV-1 infection

(2017) Jyh Liang Hor et al.   Scientific Reports

CD8+T Cells Play a Bystander Role in Mice Latently Infected with Herpes Simplex Virus 1

(2016) Kevin R. Mott et al.   JOURNAL OF VIROLOGY

STAT1 Signaling within Macrophages Is Required for Antifungal Activity against Cryptococcus neoformans

(2015) Chrissy M. Leopold Wager et al.   INFECTION AND IMMUNITY

Interferon-γ Inhibits Ebola Virus Infection

(2015) Bethany A. Rhein et al.   PLoS Pathogens

Innate and Adaptive Immune Regulation During Chronic Viral Infections

(2015) Elina I. Zuniga et al.   Annual Review of Virology

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice

(2014) Clare L. Abram et al.   JOURNAL OF IMMUNOLOGICAL METHODS

JNK MAPK Pathway Regulates Constitutive Transcription of CCL5 by Human NK Cells through SP1

(2014) D. Kumar et al.   JOURNAL OF IMMUNOLOGY

IRF7-Dependent Type I Interferon Production Induces Lethal Immune-Mediated Disease in STAT1 Knockout Mice Infected with Lymphocytic Choriomeningitis Virus

(2014) W. Li et al.   JOURNAL OF VIROLOGY

Inducible, Dose-Adjustable and Time-Restricted Reconstitution of Stat1 Deficiency In Vivo

(2014) Nicole R. Leitner et al.   PLoS One

Commensal microbes and interferon-  determine persistence of enteric murine norovirus infection

(2014) M. T. Baldridge et al.   SCIENCE

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

An Inquiry into the Molecular Basis of HSV Latency and Reactivation

(2013) Bernard Roizman et al.   Annual Review of Microbiology

Interactions between Herpesvirus Entry Mediator (TNFRSF14) and Latency-Associated Transcript during Herpes Simplex Virus 1 Latency

(2013) S. J. Allen et al.   JOURNAL OF VIROLOGY

Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages

(2013) Wei Ying et al.   Jove-Journal of Visualized Experiments

Into the Eye of the Cytokine Storm

(2012) J. R. Tisoncik et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Pathogenesis of herpes stromal keratitis – A focus on corneal neovascularization

(2012) Fernanda Giménez et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Transcriptional regulation by STAT6

(2011) Shreevrat Goenka et al.   IMMUNOLOGIC RESEARCH

Early Responding Dendritic Cells Direct the Local NK Response To Control Herpes Simplex Virus 1 Infection within the Cornea

(2011) G. M. Frank et al.   JOURNAL OF IMMUNOLOGY

Functional Genomics Reveals an Essential and Specific Role for Stat1 in Protection of the Central Nervous System following Herpes Simplex Virus Corneal Infection

(2011) T. J. Pasieka et al.   JOURNAL OF VIROLOGY

Generation of mice with a conditional Stat1 null allele

(2011) Barbara Wallner et al.   TRANSGENIC RESEARCH

A novel form of human STAT1 deficiency impairing early but not late responses to interferons

(2010) X.-F. Kong et al.   BLOOD

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Depletion of Gr-1+, but not Ly6G+, immune cells exacerbates virus replication and disease in an intranasal model of herpes simplex virus type 1 infection

(2010) M. Wojtasiak et al.   JOURNAL OF GENERAL VIROLOGY

The macrophage in HIV-1 infection: From activation to deactivation?

(2010) Georges Herbein et al.   Retrovirology

Contribution of Macrophages to Angiogenesis Induced by Vascular Endothelial Growth Factor Receptor-3-Specific Ligands

(2009) Eui-Sang Chung et al.   AMERICAN JOURNAL OF PATHOLOGY

Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases

(2009) Xiaoyu Hu et al.   IMMUNITY

A partial form of recessive STAT1 deficiency in humans

(2009) Ariane Chapgier et al.   JOURNAL OF CLINICAL INVESTIGATION

A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages

(2009) Kevin R Mott et al.   Virology Journal

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Role of Dendritic Cells in Enhancement of Herpes Simplex Virus Type 1 Latency and Reactivation in Vaccinated Mice

(2008) K. R. Mott et al.   Clinical and Vaccine Immunology

Host Responses to Wild-Type and Attenuated Herpes Simplex Virus Infection in the Absence of Stat1

(2008) T. J. Pasieka et al.   JOURNAL OF VIROLOGY

Traffic of leukocytes in the central nervous system is associated with chemokine up-regulation in a severe model of herpes simplex encephalitis: An intravital microscopy study

(2008) Márcia Carvalho Vilela et al.   NEUROSCIENCE LETTERS