Selective Ni-catalyzed cross-electrophile coupling of alkynes, fluoroalkyl halides, and vinyl halides

Copper Catalyzed Three‐component Reactions of 2‐Iodo‐2,2‐difluoroacetophenones, Alkynes and Trimethylsilyl Cyanide

(2021) Pingjie Wu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Nickel-catalyzed site- and stereoselective reductive alkylalkynylation of alkynes

(2021) Yi Jiang et al.   Chem

Hydrogen-Bonding Controlled Nickel-Catalyzed Regioselective Cyclotrimerization of Terminal Alkynes

(2021) Kai Yang et al.   ORGANIC LETTERS

Pd-Catalyzed Perfluoroalkylative Aryloxycarbonylation of Alkynes with Formates as CO Surrogates

(2021) Beata Gatlik et al.   ACS Catalysis

Three-Component Coupling of Acyl Fluorides, Silyl Enol Ethers, and Alkynes by P(III)/P(V) Catalysis

(2021) Hayato Fujimoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalyzing the Hydrodefluorination of CF3-Substituted Alkenes by PhSiH3. H• Transfer from a Nickel Hydride

(2020) Chengbo Yao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Difluoroalkylated Benzofuran, Benzothiophene, and Indole Derivatives via Palladium-Catalyzed Cascade Difluoroalkylation and Arylation of 1,6-Enynes

(2020) Pengbo Zhang et al.   ORGANIC LETTERS

Recent Advances in Nickel-Catalyzed Three-Component Difunctionalization of Unactivated Alkenes

(2020) Hai-Yong Tu et al.   SYNTHESIS-STUTTGART

Mechanisms of Nickel-Catalyzed Coupling Reactions and Applications in Alkene Functionalization

(2020) Justin Diccianni et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nickel‐Catalyzed Dicarbofunctionalization of Alkenes †

(2020) Yun‐Cheng Luo et al.   CHINESE JOURNAL OF CHEMISTRY

Nickel-Catalyzed Enantioselective Reductive Cross-Coupling Reactions

(2020) Kelsey E. Poremba et al.   ACS Catalysis

Nickel-Catalyzed Dicarbofunctionalization of Alkenes

(2020) Xiaoxu Qi et al.   ACS Catalysis

Cross-Electrophile Couplings of Activated and Sterically Hindered Halides and Alcohol Derivatives

(2020) Jiandong Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

General Method for Enantioselective Three-Component Carboarylation of Alkenes Enabled by Visible-Light Dual Photoredox/Nickel Catalysis

(2020) Lei Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ynoate-Initiated Selective C–N Esterification of Tertiary Amines under Transition-Metal and Oxidant-Free Conditions

(2020) Huangdi Feng et al.   SYNLETT

Selective, Intermolecular Alkylarylation of Alkenes via Photoredox/Nickel Dual Catalysis

(2019) Lei Guo et al.   ORGANIC LETTERS

Mechanistic Investigation of Enantioconvergent Kumada Reactions of Racemic α-Bromoketones Catalyzed by a Nickel/Bis(oxazoline) Complex

(2019) Haolin Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper(I)-Catalyzed Cyanoperfluoroalkylation of Alkynes

(2019) Muhammad Israr et al.   ORGANIC LETTERS

Visible-Light-Enabled Stereodivergent Synthesis of E - and Z -Configured 1,4-Dienes by Photoredox/Nickel Dual Catalysis

(2019) Fan Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism of Ni-Catalyzed Reductive 1,2-Dicarbofunctionalization of Alkenes

(2019) Qiao Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium‐Catalyzed Carboperfluoroalkylation of Alkynes with Fluoroalkyl Iodides and Arylstannanes

(2019) Nitinkumar Satyadev Upadhyay et al.   ADVANCED SYNTHESIS & CATALYSIS

Trifluoromethylation of Electron-Rich Alkenyl Iodides with Fluoroform-Derived “Ligandless” CuCF3

(2018) Jordi Mestre et al.   JOURNAL OF ORGANIC CHEMISTRY

Transition-Metal (Cu, Pd, Ni)-Catalyzed Difluoroalkylation via Cross-Coupling with Difluoroalkyl Halides

(2018) Zhang Feng et al.   ACCOUNTS OF CHEMICAL RESEARCH

Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay

(2018) Xian Zhao et al.   Nature Communications

syn-Selective alkylarylation of terminal alkynes via the combination of photoredox and nickel catalysis

(2018) Lei Guo et al.   Nature Communications

Fluoroalkylation–Borylation of Alkynes: An Efficient Method To Obtain (Z)-Tri- and Tetrasubstituted Fluoroalkylated Alkenylboronates

(2018) Wen-Hao Guo et al.   ACS Catalysis

Palladium-Catalyzed Selective Synthesis of Perfluoroalkylated Enynes from Perfluoroalkyl Iodides and Alkynes

(2017) Xinxin Qi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Nickel-Catalyzed Asymmetric Reductive Cross-Coupling To Access 1,1-Diarylalkanes

(2017) Kelsey E. Poremba et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Preformulation studies for nortriptyline

(2017) Ionuţ Ledeţi et al.   JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY

Copper-Catalyzed C–H Difluoroalkylations and Perfluoroalkylations of Alkenes and (Hetero)arenes

(2017) Xiaoyang Wang et al.   ORGANIC LETTERS

Transition-metal-free direct perfluoroalkylation of quinoline amides at C5 position through radical cross-coupling under mild conditions

(2017) Jun Xu et al.   Organic Chemistry Frontiers

Controlled Fluoroalkylation Reactions by Visible-Light Photoredox Catalysis

(2016) Tanmay Chatterjee et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cross-Electrophile Coupling of Vinyl Halides with Alkyl Halides

(2016) Keywan A. Johnson et al.   CHEMISTRY-A EUROPEAN JOURNAL

Homodimericin A: A Complex Hexacyclic Fungal Metabolite

(2016) Emily Mevers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of β-Difluoroalkylated Acrylonitriles in the Presence of Copper Powder

(2016) Yu-Tao He et al.   ORGANIC LETTERS

Palladium-Catalyzed Regioselective Difluoroalkylation and Carbonylation of Alkynes

(2016) Qiang Wang et al.   ORGANIC LETTERS

A Broadly Applicable Method for Pd-Catalyzed Carboperfluoro-alkylation of Terminal and Internal Alkynes: A Convenient Route to Tri- and Tetrasubstituted Olefins

(2016) Sylwester Domański et al.   ACS Catalysis

Decarboxylative Perfluoroalkylation of Vinyl Bromides with Copper(I) Perfluorocarboxylato Complexes

(2016) Chuyi Wu et al.   Asian Journal of Organic Chemistry

Methods and Mechanisms for Cross-Electrophile Coupling of Csp2 Halides with Alkyl Electrophiles

(2015) Daniel J. Weix   ACCOUNTS OF CHEMICAL RESEARCH

Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity

(2015) Ruth Dorel et al.   CHEMICAL REVIEWS

Pd-Catalyzed Difluoromethylation of Vinyl Bromides, Triflates, Tosylates, and Nonaflates

(2015) Dalu Chang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Progress toward the Introduction of Functionalized Difluoromethylated Building Blocks onto C(sp2) and C(sp) Centers

(2015) Marie-Charlotte Belhomme et al.   CHEMISTRY-A EUROPEAN JOURNAL

Direct Vicinal Difunctionalization of Alkynes: An Efficient Approach Towards the Synthesis of Highly Functionalized Fluorinated Alkenes

(2015) Tatiana Besset et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Pd-Catalyzed Stereoselective Carboperfluoroalkylation of Alkynes

(2015) Zhaodong Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Intermolecular Aryldifluoroalkylation of Alkynes

(2015) Yu-Tao He et al.   ORGANIC LETTERS

Oxidative Trifluoromethylation and Trifluoromethylthiolation Reactions Using (Trifluoromethyl)trimethylsilane as a Nucleophilic CF3 Source

(2014) Lingling Chu et al.   ACCOUNTS OF CHEMICAL RESEARCH

A General Synthesis of Fluoroalkylated Alkenes by Palladium-Catalyzed Heck-Type Reaction of Fluoroalkyl Bromides

(2014) Zhang Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modern Carbon–Fluorine Bond Forming Reactions for Aryl Fluoride Synthesis

(2014) Michael G. Campbell et al.   CHEMICAL REVIEWS

Reductive Cross-Coupling Reactions between Two Electrophiles

(2014) Christiane E. I. Knappke et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cross-Electrophile Coupling: Principles of Reactivity and Selectivity

(2014) Daniel A. Everson et al.   JOURNAL OF ORGANIC CHEMISTRY

Nickel-Catalyzed Negishi Arylations of Propargylic Bromides: A Mechanistic Investigation

(2014) Nathan D. Schley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Industrial Applications of the Diels-Alder Reaction

(2013) Jacques-Alexis Funel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemicals from Alkynes with Palladium Catalysts

(2013) Rafael Chinchilla et al.   CHEMICAL REVIEWS

Bimetallic Oxidative Addition Involving Radical Intermediates in Nickel-Catalyzed Alkyl–Alkyl Kumada Coupling Reactions

(2013) Jan Breitenfeld et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism and Selectivity in Nickel-Catalyzed Cross-Electrophile Coupling of Aryl Halides with Alkyl Halides

(2013) Soumik Biswas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Reductive Acyl Cross-Coupling: Synthesis of Enantioenriched Acyclic α,α-Disubstituted Ketones

(2013) Alan H. Cherney et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Decarboxylative Trifluoromethylation of Allylic Bromodifluoroacetates

(2013) Brett R. Ambler et al.   ORGANIC LETTERS

Living Anionic Polymerization of Benzofulvene: Highly Reactive Fixed Transoid 1,3-Diene

(2013) Yuki Kosaka et al.   ACS Macro Letters

Tamed Arene and Heteroarene Trifluoromethylation

(2012) Tatiana Besset et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Mediated Difluoromethylation of (Hetero)aryl Iodides and β-Styryl Halides with Tributyl(difluoromethyl)stannane

(2012) G. K. Surya Prakash et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radical Cascades Initiated by Intermolecular Radical Addition to Alkynes and Related Triple Bond Systems

(2012) Uta Wille   CHEMICAL REVIEWS

Palladium-Mediated Heck-Type Reactions of [(Bromodifluoromethyl)sulfonyl]benzene: Synthesis of α-Alkenyl- and α-Heteroaryl-Substituted α,α-Difluoromethyl Phenyl Sulfones

(2012) Nakin Surapanich et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Discovery of Novel 5,5-Diarylpentadienamides as Orally Available Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists

(2012) Osamu Saku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Copper-Mediated Difluoromethylation of Aryl and Vinyl Iodides

(2012) Patrick S. Fier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric 1,2-Reduction of Enones with Potassium Borohydride Catalyzed by Chiral N,N′-Dioxide–Scandium(III) Complexes

(2012) Peng He et al.   ORGANIC LETTERS

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

The sorbicillinoid family of natural products: Isolation, biosynthesis, and synthetic studies

(2011) Andrew M. Harned et al.   NATURAL PRODUCT REPORTS

Catalysis for fluorination and trifluoromethylation

(2011) Takeru Furuya et al.   NATURE

Nickel-Catalyzed Reductive Cross-Coupling of Aryl Halides with Alkyl Halides

(2010) Daniel A. Everson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS