Synthesis of active pharmaceutical ingredients using electrochemical methods: keys to improve sustainability

Reproducibility in Electro‐organic Synthesis – Myths and Misunderstandings

(2021) Sebastian Beil et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemically Enabled One‐Pot Multistep Synthesis of C19 Androgen Steroids

(2021) Florian Sommer et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organic Electrochemistry: Molecular Syntheses with Potential

(2021) Cuiju Zhu et al.   ACS Central Science

Synthesis of Morphinans through Anodic Aryl‐Aryl Coupling

(2021) Nina Vierengel et al.   CHEMICAL RECORD

Scalable Flow Electrochemical Alcohol Oxidation: Maintaining High Stereochemical Fidelity in the Synthesis of Levetiracetam

(2021) Xing Zhong et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Chemoselective Electrochemical Oxidation of Secondary Alcohols using a Recyclable Chloride-Based Mediator

(2021) Florian Sommer et al.   SYNLETT

Evolution of Earth‐Abundant 3 d‐Metallaelectro‐Catalyzed C−H Activation: From Chelation‐Assistance to C−H Functionalization without Directing Groups

(2021) Ramesh C. Samanta et al.   CHEMICAL RECORD

Constant Potential and Constant Current Electrolysis: An Introduction and Comparison of Different Techniques for Organic Electrosynthesis

(2021) Mohammad Rafiee et al.   JOURNAL OF ORGANIC CHEMISTRY

“How Should I Think about Voltage? What Is Overpotential?”: Establishing an Organic Chemistry Intuition for Electrochemistry

(2021) Jordan E. Nutting et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalyzing Electrosynthesis: A Homogeneous Electrocatalytic Approach to Reaction Discovery

(2020) Juno C. Siu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Transition Metal-Mediated C-C Single Bond Cleavage: Making the Cut in Total Synthesis

(2020) Richmond Sarpong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Is electrosynthesis always green and advantageous compared to traditional methods?

(2020) Yong Yuan et al.   Nature Communications

Translating batch electrochemistry to single-pass continuous flow conditions: an organic chemist’s guide

(2020) Snjezana Maljuric et al.   Journal of Flow Chemistry

An Electrochemical Flow-Through Cell for Rapid Reactions

(2020) Matthias Lehmann et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Electrode Materials in Modern Organic Electrochemistry

(2020) David Heard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemical N-Demethylation of 14-Hydroxy Morphinans: Sustainable Access to Opioid Antagonists

(2020) Gabriel Glotz et al.   ORGANIC LETTERS

A Continuous Flow Cell for High‐Temperature/High‐Pressure Electroorganic Synthesis

(2020) Wolfgang Jud et al.   ChemElectroChem

Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes

(2020) George L. Bakris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Powering the Future: How Can Electrochemistry Make a Difference in Organic Synthesis?

(2020) Tjark H. Meyer et al.   Chem

Bridging Lab and Industry with Flow Electrochemistry

(2020) Nour Tanbouza et al.   iScience

Unraveling Two Pathways for Electrochemical Alcohol and Aldehyde Oxidation on NiOOH

(2020) Michael T. Bender et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Harnessing Radical Chemistry via Electrochemical Transition Metal Catalysis

(2020) Jiaqing Lu et al.   iScience

Gas bubbles have controversial effects on Taylor flow electrochemistry

(2020) Yiran Cao et al.   CHEMICAL ENGINEERING JOURNAL

Scalable and safe synthetic organic electroreduction inspired by Li-ion battery chemistry

(2019) Byron K. Peters et al.   SCIENCE

Total Synthesis of (−)-Oxycodone via Anodic Aryl–Aryl Coupling

(2019) Alexander Lipp et al.   ORGANIC LETTERS

Organic Electrosynthesis: Applications in Complex Molecule Synthesis

(2019) Andrey Shatskiy et al.   ChemElectroChem

The Fundamentals Behind the Use of Flow Reactors in Electrochemistry

(2019) Timothy Noël et al.   ACCOUNTS OF CHEMICAL RESEARCH

Basic Strategies and Types of Applications in Organic Electrochemistry

(2019) Gerhard Hilt   ChemElectroChem

A Regio- and Diastereoselective Anodic Aryl-Aryl Coupling in the Biomimetic Total Synthesis of (−)-Thebaine

(2018) Alexander Lipp et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrifying Organic Synthesis

(2018) Anton Wiebe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetramethylpiperidine N-Oxyl (TEMPO), Phthalimide N-Oxyl (PINO), and Related N-Oxyl Species: Electrochemical Properties and Their Use in Electrocatalytic Reactions

(2018) Jordan E. Nutting et al.   CHEMICAL REVIEWS

Electrochemical strategies for C–H functionalization and C–N bond formation

(2018) Markus D. Kärkäs   CHEMICAL SOCIETY REVIEWS

Organic electrosynthesis – A road to greater application. A mini review

(2018) Derek Pletcher   ELECTROCHEMISTRY COMMUNICATIONS

Electrochemical Oxidation of Alcohols and Aldehydes to Carboxylic Acids Catalyzed by 4-Acetamido-TEMPO: An Alternative to “Anelli” and “Pinnick” Oxidations

(2018) Mohammad Rafiee et al.   ACS Catalysis

Organic Electrosynthesis: From Laboratorial Practice to Industrial Applications

(2017) David S. P. Cardoso et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Electrochemical Alcohol Oxidation Mediated by TEMPO-like Nitroxyl Radicals

(2017) Rosaria Ciriminna et al.   ChemistryOpen

Bi(OTf)3 -Catalysed Access to 2,3-Substituted Isoindolinones and Tricyclic N,O-Acetals by Trapping of Bis-N -Acyliminium Species in a Tandem Process

(2016) Ahmed Aliyenne et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Electrosynthesis in extended channel length microfluidic electrolysis cells

(2016) Robert A. Green et al.   Journal of Flow Chemistry

Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method

(2016) Evan J. Horn et al.   ACS Central Science

Electrolytic Macrocyclizations: Scalable Synthesis of a Diazonamide-Based Drug Development Candidate

(2015) Hui Ding et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemical flow-reactor for expedient synthesis of copper–N-heterocyclic carbene complexes

(2015) Michael R. Chapman et al.   CHEMICAL COMMUNICATIONS

A Novel Cathode Material for Cathodic Dehalogenation of 1,1-Dibromo Cyclopropane Derivatives

(2015) Christoph Gütz et al.   CHEMISTRY-A EUROPEAN JOURNAL

Towards a holistic approach to metrics for the 21st century pharmaceutical industry

(2015) C. Robert McElroy et al.   GREEN CHEMISTRY

Development and Scale-Up of the Electrochemical Dehalogenation for the Synthesis of a Key Intermediate for NS5A Inhibitors

(2015) Christoph Gütz et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Electrochemical Synthesis in Microreactors

(2015) Kevin Watts et al.   Journal of Flow Chemistry

Renaissance of Electrosynthetic Methods for the Construction of Complex Molecules

(2014) Siegfried R. Waldvogel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox catalysis in organic electrosynthesis: basic principles and recent developments

(2014) Robert Francke et al.   CHEMICAL SOCIETY REVIEWS

Total Synthesis of Dixiamycin B by Electrochemical Oxidation

(2014) Brandon R. Rosen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nucleophilic substitution of the acetoxy group in 3-methylbenzoylaminomethyl acetate

(2012) L. Labanauskas et al.   RUSSIAN CHEMICAL BULLETIN

Contributions of organic electrosynthesis to green chemistry

(2011) Hans J. Schäfer   COMPTES RENDUS CHIMIE

Organic electrosynthesis: a promising green methodology in organic chemistry

(2010) Bernardo A. Frontana-Uribe et al.   GREEN CHEMISTRY

Electrochemical microstructured reactors: design and application in organic synthesis

(2009) A. Ziogas et al.   JOURNAL OF APPLIED ELECTROCHEMISTRY

Electrochemical routes for industrial synthesis

(2009) C. A. C. Sequeira et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY