PI3K/ NF-κB-dependent TNF-α and HDAC activities facilitate LPS-induced RGS10 suppression in pulmonary macrophages

Cigarette smoke extract-induced downregulation of p300 is responsible for the impaired inflammatory cytokine response of macrophages

(2021) Kyoung-Hee Lee et al.   CELLULAR SIGNALLING

Inhibition of regulator of G protein signaling 10, aggravates rheumatoid arthritis progression by promoting NF-κB signaling pathway

(2021) Jie Ren et al.   MOLECULAR IMMUNOLOGY

Microglia Mediated Neuroinflammation: Focus on PI3K Modulation

(2020) Antonia Cianciulli et al.   Biomolecules

RGS10 and RGS18 differentially limit platelet activation, promote platelet production, and prolong platelet survival

(2020) Daniel J DeHelian et al.   BLOOD

A Global Map of G Protein Signaling Regulation by RGS Proteins

(2020) Ikuo Masuho et al.   CELL

Macrophages and the maintenance of homeostasis

(2020) David M. Mosser et al.   Cellular & Molecular Immunology

TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury

(2020) Shun Xu et al.   Cell Death & Disease

Gαi2 Signaling Regulates Inflammasome Priming and Cytokine Production by Biasing Macrophage Phenotype Determination

(2019) Ali Vural et al.   JOURNAL OF IMMUNOLOGY

Epigenetic regulation of macrophages: from homeostasis maintenance to host defense

(2019) Siyuan Chen et al.   Cellular & Molecular Immunology

Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner

(2018) Moumita Datta et al.   IMMUNITY

Genetic Analysis of Rare Human Variants of Regulators of G Protein Signaling Proteins and Their Role in Human Physiology and Disease

(2018) Katherine E. Squires et al.   PHARMACOLOGICAL REVIEWS

Histone deacetylase 2 is essential for LPS-induced inflammatory responses in macrophages

(2018) Chenming Wu et al.   IMMUNOLOGY AND CELL BIOLOGY

RGS10 Regulates the Expression of Cyclooxygenase-2 and Tumor Necrosis Factor Alpha through a G Protein–Independent Mechanism

(2018) Mohammed Alqinyah et al.   MOLECULAR PHARMACOLOGY

CNS inflammation and neurodegeneration

(2017) Tanuja Chitnis et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of histone deacetylase 1 or 2 reduces induced cytokine expression in microglia through a protein synthesis independent mechanism

(2017) Benjamin S. Durham et al.   JOURNAL OF NEUROCHEMISTRY

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis

(2016) Jae-Kyung Lee et al.   Journal of Neuroinflammation

Regulator of G Protein Signaling 10 ( Rgs10 ) Expression Is Transcriptionally Silenced in Activated Microglia by Histone Deacetylase Activity

(2016) Mohammed Alqinyah et al.   MOLECULAR PHARMACOLOGY

RGS10 Negatively Regulates Platelet Activation and Thrombogenesis

(2016) Nicole R. Hensch et al.   PLoS One

The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

(2016) Anja Henn   ALTEX-Alternatives to Animal Experimentation

Diseases of Pulmonary Surfactant Homeostasis

(2015) Jeffrey A. Whitsett et al.   Annual Review of Pathology-Mechanisms of Disease

Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells

(2015) Molly K. Altman et al.   CANCER LETTERS

Protein Lysine Acetylation by p300/CBP

(2015) Beverley M. Dancy et al.   CHEMICAL REVIEWS

Cellular deficiency in the RGS10 protein facilitates chemoresistant ovarian cancer

(2015) Shelley B Hooks et al.   Future Medicinal Chemistry

Regulator of G-Protein Signaling 10 Negatively Regulates Cardiac Remodeling by Blocking Mitogen-Activated Protein Kinase–Extracellular Signal-Regulated Protein Kinase 1/2 SignalingNovelty and Significance

(2015) Rujia Miao et al.   HYPERTENSION

The development and function of lung-resident macrophages and dendritic cells

(2015) Manfred Kopf et al.   NATURE IMMUNOLOGY

Histone exchange, chromatin structure and the regulation of transcription

(2015) Swaminathan Venkatesh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

KAT5-mediated SOX4 acetylation orchestrates chromatin remodeling during myoblast differentiation

(2015) S-M Jang et al.   Cell Death & Disease

Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity

(2014) Kristin Westphalen et al.   NATURE

Inhibition of Rgs10 Expression Prevents Immune Cell Infiltration in Bacteria-induced Inflammatory Lesions and Osteoclast-mediated Bone Destruction

(2014) Sen Yang et al.   Bone Research

Role of alveolar macrophages in chronic obstructive pulmonary disease

(2014) Ross Vlahos   Frontiers in Immunology

Downregulation of NO and PGE2 in LPS-stimulated BV2 microglial cells by trans-isoferulic acid via suppression of PI3K/Akt-dependent NF-κB and activation of Nrf2-mediated HO-1

(2013) Matharage Gayani Dilshara et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Protein Kinase CK2 Regulates the Dimerization of Histone Deacetylase 1 (HDAC1) and HDAC2 during Mitosis

(2013) Dilshad H. Khan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

DNA methylation: roles in mammalian development

(2013) Zachary D. Smith et al.   NATURE REVIEWS GENETICS

Transcriptional Suppression, DNA Methylation, and Histone Deacetylation of the Regulator of G-Protein Signaling 10 (RGS10) Gene in Ovarian Cancer Cells

(2013) Mourad W. Ali et al.   PLoS One

Critical Role of Regulator G-Protein Signaling 10 (RGS10) in Modulating Macrophage M1/M2 Activation

(2013) Jae-Kyung Lee et al.   PLoS One

Acetylation of Retinal Histones in Diabetes Increases Inflammatory Proteins

(2012) Chandra Sekhar Rao Kadiyala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RGS10 exerts a neuroprotective role through the PKA/c-AMP response-element (CREB) pathway in dopaminergic neuron-like cells

(2012) Jae-Kyung Lee et al.   JOURNAL OF NEUROCHEMISTRY

Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update

(2012) John M. Kyriakis et al.   PHYSIOLOGICAL REVIEWS

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

(2012) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors

(2012) Geneviève P Delcuve et al.   Clinical Epigenetics

The NF-κB Subunit c-Rel Stimulates Cardiac Hypertrophy and Fibrosis

(2011) Silvia Gaspar-Pereira et al.   AMERICAN JOURNAL OF PATHOLOGY

Multiple Facets of NF-κB in the Heart

(2011) Joseph W. Gordon et al.   CIRCULATION RESEARCH

RGS10 Restricts Upregulation by Chemokines of T Cell Adhesion Mediated by  4 1 and  L 2 Integrins

(2011) D. Garcia-Bernal et al.   JOURNAL OF IMMUNOLOGY

Regulator of G-Protein Signaling-10 Negatively Regulates NF- B in Microglia and Neuroprotects Dopaminergic Neurons in Hemiparkinsonian Rats

(2011) J.-K. Lee et al.   JOURNAL OF NEUROSCIENCE

Histone Deacetylase-3 Activation Promotes Tumor Necrosis Factor-α (TNF-α) Expression in Cardiomyocytes during Lipopolysaccharide Stimulation

(2010) Huaqing Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coactivation of the CLOCK-BMAL1 complex by CBP mediates resetting of the circadian clock

(2010) Y. Lee et al.   JOURNAL OF CELL SCIENCE

Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells

(2010) Shelley B Hooks et al.   Molecular Cancer

Chemical phylogenetics of histone deacetylases

(2010) James E Bradner et al.   Nature Chemical Biology

Regulator of G-Protein Signaling 10 Promotes Dopaminergic Neuron Survival via Regulation of the Microglial Inflammatory Response

(2008) J.-K. Lee et al.   JOURNAL OF NEUROSCIENCE

A role for RGS10 in β-adrenergic modulation of G-protein-activated K+(GIRK) channel current in rat atrial myocytes

(2008) Kirsten Bender et al.   JOURNAL OF PHYSIOLOGY-LONDON