TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury

Long noncoding RNA LINC00339 promotes renal tubular epithelial pyroptosis by regulating the miR-22-3p/NLRP3 axis in calcium oxalate-induced kidney stone

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LncRNA H19 initiates microglial pyroptosis and neuronal death in retinal ischemia/reperfusion injury

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(2019) Grégoire Courtine et al.   NATURE MEDICINE

Long Non-coding RNA MALAT1 Inhibits Neuron Apoptosis and Neuroinflammation While Stimulates Neurite Outgrowth and Its Correlation With MiR-125b Mediates PTGS2, CDK5 and FOXQ1 in Alzheimer's Disease

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TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease

(2019) Youliang Wang et al.   Frontiers in Endocrinology

Type I collagen or gelatin stimulates mouse peritoneal macrophages to aggregate and produce pro-inflammatory molecules through upregulated ROS levels

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Inflammasome: Its role in traumatic brain and spinal cord injury

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Inducible knockdown of procollagen I protects mice from liver fibrosis and leads to dysregulated matrix genes and attenuated inflammation

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The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways

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Nurr1: A vital participant in the TLR4-NF-κB signal pathway stimulated by α-synuclein in BV-2 cells

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Crosstalk among lncRNAs, microRNAs and mRNAs in the muscle ‘degradome’ of rainbow trout

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Paeonol Inhibits IL-1β-Induced Inflammation via PI3K/Akt/NF-κB Pathways: In Vivo and Vitro Studies

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Dl-3-n-butylphthalide attenuates acute inflammatory activation in rats with spinal cord injury by inhibiting microglial TLR4/NF-κB signalling

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Long Noncoding RNA Malat1 Regulates Cerebrovascular Pathologies in Ischemic Stroke

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Long Noncoding RNA LINC00673 Is Activated by SP1 and Exerts Oncogenic Properties by Interacting with LSD1 and EZH2 in Gastric Cancer

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The long noncoding RNA Malat1: Its physiological and pathophysiological functions

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Long Noncoding RNAs in Cancer Pathways

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The Long Non-Coding RNAs in Neurodegenerative Diseases: Novel Mechanisms of Pathogenesis

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Macrophage polarization: a key event in the secondary phase of acute spinal cord injury

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Competing endogenous RNAs: a target-centric view of small RNA regulation in bacteria

(2016) Lionello Bossi et al.   NATURE REVIEWS MICROBIOLOGY

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Long noncoding RNAs (lncRNAs) and the molecular hallmarks of aging

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Immunotherapy Strategies for Spinal Cord Injury

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Role of Toll like receptor 4 signaling pathway in the secondary damage induced by experimental spinal cord injury

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Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model

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The role of inflammation in perinatal brain injury

(2015) Henrik Hagberg et al.   Nature Reviews Neurology

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Priming the Inflammatory Pump of the CNS after Traumatic Brain Injury

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Toll-like receptor 4 is associated with seizures following ischemia with hyperglycemia

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STAT1 plays a role in TLR signal transduction and inflammatory responses

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Toll-Like Receptor 4-Dependent Microglial Activation Mediates Spinal Cord Ischemia-Reperfusion Injury

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Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

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A Molecular Platform in Neurons Regulates Inflammation after Spinal Cord Injury

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