Hippo/YAP signaling pathway protects against neomycin-induced hair cell damage in the mouse cochlea

Dynamic patterns of YAP1 expression and cellular localization in the developing and injured utricle

(2021) Vikrant Borse et al.   Scientific Reports

YAP Mediates Hair Cell Regeneration in Balance Organs of Chickens, But LATS Kinases Suppress Its Activity in Mice

(2020) Mark A. Rudolf et al.   JOURNAL OF NEUROSCIENCE

Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal

(2020) Ksenia Gnedeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Mechanism of Hippo–YAP1/TAZ Pathway in Heart Development, Disease, and Regeneration

(2020) Xiaoqing Chen et al.   Frontiers in Physiology

VGLL4 Protects against Oxidized-LDL-Induced Endothelial Cell Dysfunction and Inflammation by Activating Hippo-YAP/TEAD1 Signaling Pathway

(2020) Kaicheng Xu et al.   MEDIATORS OF INFLAMMATION

New molecular therapies for the treatment of hearing loss

(2019) Yutian Ma et al.   PHARMACOLOGY & THERAPEUTICS

Pharmacological Inhibition of Hippo Pathway using XMU‐MP‐1 Protects The Heart Against Adverse Effects during Pressure Overload

(2019) Efta Triastuti et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Hippo Signaling Pathway in Development and Disease

(2019) Yonggang Zheng et al.   DEVELOPMENTAL CELL

Increased oxidative stress, inflammation, and glutamate: Potential preventive and therapeutic targets for hearing disorders

(2019) Kadar N. Prasad et al.   MECHANISMS OF AGEING AND DEVELOPMENT

YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration

(2018) Shiro Yui et al.   Cell Stem Cell

The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration

(2018) Jun Wang et al.   Nature Reviews Cardiology

Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine

(2018) Iván M. Moya et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanobiology of YAP and TAZ in physiology and disease

(2017) Tito Panciera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hearing Loss in Adults

(2017) Lisa L. Cunningham et al.   NEW ENGLAND JOURNAL OF MEDICINE

NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in the HeartNovelty and Significance

(2016) Takahisa Matsuda et al.   CIRCULATION RESEARCH

Non-Photoinduced Biological Properties of Verteporfin

(2016) Floriane Gibault et al.   CURRENT MEDICINAL CHEMISTRY

Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye

(2016) Jin Young Kim et al.   DEVELOPMENTAL BIOLOGY

Photodynamic therapy: current role in the treatment of chorioretinal conditions

(2016) D K Newman   EYE

Fluorescent aminoglycosides reveal intracellular trafficking routes in mechanosensory hair cells

(2016) Dale W. Hailey et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration

(2016) Fuqin Fan et al.   Science Translational Medicine

New insights into posttranslational modifications of Hippo pathway in carcinogenesis and therapeutics

(2016) Mingjing He et al.   Cell Division

Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus

(2016) Raehee Park et al.   Nature Communications

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

(2015) Fa-Xing Yu et al.   CELL

The Hippo Pathway in Heart Development, Regeneration, and Diseases

(2015) Q. Zhou et al.   CIRCULATION RESEARCH

Designer aminoglycosides prevent cochlear hair cell loss and hearing loss

(2015) Markus E. Huth et al.   JOURNAL OF CLINICAL INVESTIGATION

A gp130–Src–YAP module links inflammation to epithelial regeneration

(2015) Koji Taniguchi et al.   NATURE

Molecular regulation of auditory hair cell death and approaches to protect sensory receptor cells and/or stimulate repair following acoustic trauma

(2015) Christine T. Dinh et al.   Frontiers in Cellular Neuroscience

Mechanisms of sensorineural cell damage, death and survival in the cochlea

(2015) Ann C. Y. Wong et al.   Frontiers in Aging Neuroscience

c-Abl antagonizes the YAP oncogenic function

(2014) R Keshet et al.   CELL DEATH AND DIFFERENTIATION

VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex

(2014) Wenjing Zhang et al.   CELL RESEARCH

The Hippo signaling pathway in stem cell biology and cancer

(2014) J.-S. Mo et al.   EMBO REPORTS

Inhibition of the Activation and Recruitment of Microglia-Like Cells Protects Against Neomycin-Induced Ototoxicity

(2014) Shan Sun et al.   MOLECULAR NEUROBIOLOGY

Inhibition of H3K4me2 Demethylation Protects Auditory Hair Cells from Neomycin-Induced Apoptosis

(2014) Yingzi He et al.   MOLECULAR NEUROBIOLOGY

In vivo overexpression of X-linked inhibitor of apoptosis protein protects against neomycin-induced hair cell loss in the apical turn of the cochlea during the ototoxic-sensitive period

(2014) Shan Sun et al.   Frontiers in Cellular Neuroscience

The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl

(2013) N Reuven et al.   CELL DEATH AND DIFFERENTIATION

Yes-associated Protein (YAP) Promotes Cell Survival by Inhibiting Proapoptotic Dendrin Signaling

(2013) Kirk N. Campbell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YAP and TAZ Regulate Skin Wound Healing

(2013) Min-Jung Lee et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Regulation of the Hippo pathway and implications for anticancer drug development

(2013) Hyun Woo Park et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Cotransfection of Pax2 and Math1 promote in situ cochlear hair cell regeneration after neomycin insult

(2013) Yan Chen et al.   Scientific Reports

Cisplatin and Aminoglycoside Antibiotics: Hearing Loss and Its Prevention

(2012) Jochen Schacht et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Yes-associated protein regulates the hepatic response after bile duct ligation

(2012) Haibo Bai et al.   HEPATOLOGY

New developments in aminoglycoside therapy and ototoxicity

(2011) Jing Xie et al.   HEARING RESEARCH

Intracellular mechanisms of aminoglycoside-induced cytotoxicity

(2011) Takatoshi Karasawa et al.   Integrative Biology

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

PP1A-Mediated Dephosphorylation Positively Regulates YAP2 Activity

(2011) Pei Wang et al.   PLoS One

Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32

(2011) S P Francis et al.   Cell Death & Disease

Oxidative stress caused by mitochondrial calcium overload

(2010) Tsung-I Peng et al.   Annals of the New York Academy of Sciences

Hippo signaling: growth control and beyond

(2010) G. Halder et al.   DEVELOPMENT

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

(2010) B. Zhao et al.   GENES & DEVELOPMENT

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

(2010) H. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Primary Culture and Plasmid Electroporation of the Murine Organ of Corti.

(2010) Mark Parker et al.   Jove-Journal of Visualized Experiments

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Bmi1 regulates mitochondrial function and the DNA damage response pathway

(2009) Jie Liu et al.   NATURE

Generation of highly-reactive oxygen species is closely related to hair cell damage in rat organ of corti treated with gentamicin

(2009) Y.H. Choung et al.   NEUROSCIENCE

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

A Regulatory Circuit Controlling Itch-mediated p73 Degradation by Runx

(2008) Dan Levy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Yap1 Phosphorylation by c-Abl Is a Critical Step in Selective Activation of Proapoptotic Genes in Response to DNA Damage

(2008) Dan Levy et al.   MOLECULAR CELL

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

(2008) Heng Du et al.   NATURE MEDICINE