Intracellular mechanisms of aminoglycoside-induced cytotoxicity

Drug screening for hearing loss: Using the zebrafish lateral line to screen for drugs that prevent and cause hearing loss

(2010) Henry C. Ou et al.   DRUG DISCOVERY TODAY

Assembly of outer-membrane proteins in bacteria and mitochondria

(2010) J. Tommassen   MICROBIOLOGY-SGM

Aminoglycosides Inhibit KCNQ4 Channels in Cochlear Outer Hair Cells via Depletion of Phosphatidylinositol(4,5)bisphosphate

(2010) M. G. Leitner et al.   MOLECULAR PHARMACOLOGY

Channelopathies linked to plasma membrane phosphoinositides

(2010) Diomedes E. Logothetis et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

An otoprotective role for the apoptosis inhibitor protein survivin

(2010) S K Knauer et al.   Cell Death & Disease

CLIMP-63 is a gentamicin-binding protein that is involved in drug-induced cytotoxicity

(2010) T Karasawa et al.   Cell Death & Disease

Bcl-2 Gene Therapy Prevents Aminoglycoside-Induced Degeneration of Auditory and Vestibular Hair Cells

(2009) Susanna C. Pfannenstiel et al.   AUDIOLOGY AND NEURO-OTOLOGY

Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways

(2009) Kelly N. Owens et al.   HEARING RESEARCH

Trafficking of Systemic Fluorescent Gentamicin into the Cochlea and Hair Cells

(2009) Qi Wang et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Identification of FDA-Approved Drugs and Bioactives that Protect Hair Cells in the Zebrafish (Danio rerio) Lateral Line and Mouse (Mus musculus) Utricle

(2009) Henry C. Ou et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Serine 58 of 14-3-3  Is a Molecular Switch Regulating ASK1 and Oxidant Stress-Induced Cell Death

(2009) J. Zhou et al.   MOLECULAR AND CELLULAR BIOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Do we still need the aminoglycosides?

(2008) Emanuele Durante-Mangoni et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Hsp70 Inhibits Aminoglycoside-Induced Hair Cell Death and is Necessary for the Protective Effect of Heat Shock

(2008) Mona Taleb et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

TRPV4 enhances the cellular uptake of aminoglycoside antibiotics

(2008) T. Karasawa et al.   JOURNAL OF CELL SCIENCE

Caspase-independent cell death: leaving the set without the final cut

(2008) S W G Tait et al.   ONCOGENE

The endocochlear potential depends on two K+ diffusion potentials and an electrical barrier in the stria vascularis of the inner ear

(2008) F. Nin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity

(2008) S. N. Hobbie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Introducing sense into nonsense in treatments of human genetic diseases

(2008) Liat Linde et al.   TRENDS IN GENETICS

A systemic gentamicin pathway across the stria vascularis

(2007) Chun Fu Dai et al.   HEARING RESEARCH