Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis
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Title
Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis
Authors
Keywords
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Journal
Cell Metabolism
Volume 33, Issue 12, Pages 2355-2366.e8
Publisher
Elsevier BV
Online
2021-11-29
DOI
10.1016/j.cmet.2021.11.004
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Note: Only part of the references are listed.- A pilot integrative analysis of colonic gene expression, gut microbiota and immune infiltration in primary sclerosing cholangitis-inflammatory bowel disease: association of disease with bile acid pathways
- (2020) Mohammed Nabil Quraishi et al. Journal of Crohns & Colitis
- Microbial butyrate synthesis indicates therapeutic efficacy of azathioprine in IBD patients
- (2020) M Effenberger et al. Journal of Crohns & Colitis
- Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR
- (2019) Denis A. Mogilenko et al. CELL
- Immune effects of glycolysis or oxidative phosphorylation metabolic pathway in protecting against bacterial infection
- (2019) Yan Li et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases
- (2019) Jason Lloyd-Price et al. NATURE
- Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients with Inflammatory Bowel Diseases
- (2019) Konrad Aden et al. GASTROENTEROLOGY
- Composition of the Intestinal Microbiota Determines the Outcome of Virus-Triggered Colitis in Mice
- (2019) Silvia Bolsega et al. Frontiers in Immunology
- The still uncertain identity of the channel-forming unit(s) of the mitochondrial permeability transition pore
- (2018) Christopher P. Baines et al. CELL CALCIUM
- Sex-based Differences in Incidence of Inflammatory Bowel Diseases—Pooled Analysis of Population-based Studies from Western Countries
- (2018) Shailja C. Shah et al. GASTROENTEROLOGY
- Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection
- (2018) Christoph A. Thaiss et al. SCIENCE
- Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development
- (2018) Wei-Hung Pan et al. Genome Medicine
- Genome-wide DNA Methylation in Treatment-naïve Ulcerative Colitis
- (2018) Hagar Taman et al. Journal of Crohns & Colitis
- ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING
- (2018) Konrad Aden et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Toll-like Receptor 4–Induced Glycolytic Burst in Human Monocyte-Derived Dendritic Cells Results from p38-Dependent Stabilization of HIF-1α and Increased Hexokinase II Expression
- (2018) Laure Perrin-Cocon et al. JOURNAL OF IMMUNOLOGY
- Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition
- (2018) Marcus Fulde et al. NATURE
- Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris
- (2018) et al. NATURE
- Microbiomarkers in inflammatory bowel diseases: caveats come with caviar
- (2017) Felix Sommer et al. GUT
- Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease
- (2017) Urko M Marigorta et al. NATURE GENETICS
- Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability
- (2017) Thomas Briston et al. Scientific Reports
- Cyclophilin D ablation is associated with increased end-ischemic mitochondrial hexokinase activity
- (2017) Rianne Nederlof et al. Scientific Reports
- Cyclophilin D regulates the dynamic assembly of mitochondrial ATP synthase into synthasomes
- (2017) Gisela Beutner et al. Scientific Reports
- Cyclophilin D regulates necrosis, but not apoptosis, of murine eosinophils
- (2016) Xiang Zhu et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Know your neighbor: Microbiota and host epithelial cells interact locally to control intestinal function and physiology
- (2016) Felix Sommer et al. BIOESSAYS
- From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
- (2016) Ara Koh et al. CELL
- Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan
- (2016) Andrea J. Wolf et al. CELL
- Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease
- (2016) Floris Imhann et al. GUT
- Molecular classification of Crohn's disease reveals two clinically relevant subtypes
- (2016) Matthew Weiser et al. GUT
- Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease
- (2016) Robert Häsler et al. GUT
- Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues
- (2016) Kimberly A. Krautkramer et al. MOLECULAR CELL
- The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos
- (2016) Felix Sommer et al. Cell Reports
- Genome-guided design of a defined mouse microbiota that confers colonization resistance against Salmonella enterica serovar Typhimurium
- (2016) Sandrine Brugiroux et al. Nature Microbiology
- CycleFreeFlux: efficient removal of thermodynamically infeasible loops from flux distributions
- (2015) A. A. Desouki et al. BIOINFORMATICS
- Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome
- (2015) Laurence Macia et al. Nature Communications
- Site-specific programming of the host epithelial transcriptome by the gut microbiota
- (2015) Felix Sommer et al. GENOME BIOLOGY
- Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits
- (2014) Filipe De Vadder et al. CELL
- Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
- (2014) Nagendra Singh et al. IMMUNITY
- Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
- (2014) Yael Haberman et al. JOURNAL OF CLINICAL INVESTIGATION
- TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation
- (2014) Bart Everts et al. NATURE IMMUNOLOGY
- Altered Mucus Glycosylation in Core 1 O-Glycan-Deficient Mice Affects Microbiota Composition and Intestinal Architecture
- (2014) Felix Sommer et al. PLoS One
- The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
- (2014) Pamela V. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Mitochondrial Permeability Transition Pore and Cancer: Molecular Mechanisms Involved in Cell Death
- (2014) Massimo Bonora et al. Frontiers in Oncology
- Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit
- (2013) Anita Wichmann et al. Cell Host & Microbe
- TNFα and IL-17 cooperatively stimulate glucose metabolism and growth factor production in human colorectal cancer cells
- (2013) Daniel S Straus Molecular Cancer
- Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
- (2013) Yukihiro Furusawa et al. NATURE
- In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture
- (2013) Hiroyuki Miyoshi et al. Nature Protocols
- The gut microbiota — masters of host development and physiology
- (2013) Felix Sommer et al. NATURE REVIEWS MICROBIOLOGY
- Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D
- (2012) Bo Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Hexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS production
- (2012) Rongxue Wu et al. EMBO Molecular Medicine
- Disruption of Hexokinase II–Mitochondrial Binding Blocks Ischemic Preconditioning and Causes Rapid Cardiac Necrosis
- (2011) Kirsten M.A. Smeele et al. CIRCULATION RESEARCH
- Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
- (2011) Toshiro Sato et al. GASTROENTEROLOGY
- Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons
- (2011) B. J. Haas et al. GENOME RESEARCH
- Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88
- (2011) Erik Larsson et al. GUT
- Search and clustering orders of magnitude faster than BLAST
- (2010) Robert C. Edgar BIOINFORMATICS
- Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models
- (2010) Nathan E Lewis et al. Molecular Systems Biology
- QIIME allows analysis of high-throughput community sequencing data
- (2010) J Gregory Caporaso et al. NATURE METHODS
- FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments
- (2010) Morgan N. Price et al. PLoS One
- PyNAST: a flexible tool for aligning sequences to a template alignment
- (2009) J. G. Caporaso et al. BIOINFORMATICS
- Identifying Genetic Determinants Needed to Establish a Human Gut Symbiont in Its Habitat
- (2009) Andrew L. Goodman et al. Cell Host & Microbe
- G Protein-Coupled Receptor 43 Is Essential for Neutrophil Recruitment during Intestinal Inflammation
- (2009) C. Sina et al. JOURNAL OF IMMUNOLOGY
- Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
- (2009) Kendle M. Maslowski et al. NATURE
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
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