Androgen receptor splice variant 7 functions independently of the full length receptor in prostate cancer cells

A detailed characterization of stepwise activation of the androgen receptor variant 7 in prostate cancer cells

(2021) Carlos M. Roggero et al.   ONCOGENE

Increased transcription and high translation efficiency lead to accumulation of androgen receptor splice variant after androgen deprivation therapy

(2021) Tianfang Ma et al.   CANCER LETTERS

Diverse AR Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer

(2020) Yingming Li et al.   CLINICAL CANCER RESEARCH

Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer

(2020) Shuai Gao et al.   NATURE GENETICS

Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors

(2020) Yezi Zhu et al.   ONCOGENE

Targeting the androgen receptor and overcoming resistance in prostate cancer

(2019) David J. Einstein et al.   CURRENT OPINION IN ONCOLOGY

ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer

(2019) Laura Cato et al.   CANCER CELL

Clinical Utility of Circulating Tumour Cell Androgen Receptor Splice Variant-7 Status in Metastatic Castration-resistant Prostate Cancer

(2019) Adam Sharp et al.   EUROPEAN UROLOGY

SF3B2-mediated RNA splicing drives human prostate cancer progression

(2019) Norihiko Kawamura et al.   CANCER RESEARCH

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

(2018) David A. Quigley et al.   CELL

A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer

(2018) David Y. Takeda et al.   CELL

Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing

(2018) Srinivas R. Viswanathan et al.   CELL

Androgen receptor splice variants bind to constitutively open chromatin and promote abiraterone-resistant growth of prostate cancer

(2018) Yundong He et al.   NUCLEIC ACIDS RESEARCH

Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13

(2018) Zhong Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes

(2018) Evangelia K. Papachristou et al.   Nature Communications

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer

(2018) Ling Cai et al.   MOLECULAR CELL

Alternative splicing in prostate cancer

(2018) Alec Paschalis et al.   Nature Reviews Clinical Oncology

Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer

(2018) Adam Sharp et al.   JOURNAL OF CLINICAL INVESTIGATION

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping

(2017) Joanna K. Lempiäinen et al.   MOLECULAR & CELLULAR PROTEOMICS

Endogenous androgen receptor proteomic profiling reveals genomic subcomplex involved in prostate tumorigenesis

(2017) S Stelloo et al.   ONCOGENE

Interplay between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediates Castration Resistance

(2016) Yang Zhan et al.   MOLECULAR CANCER RESEARCH

Rapid immunoprecipitation mass spectrometry of endogenous proteins (RIME) for analysis of chromatin complexes

(2016) Hisham Mohammed et al.   Nature Protocols

Association of AR-V7 on Circulating Tumor Cells as a Treatment-Specific Biomarker With Outcomes and Survival in Castration-Resistant Prostate Cancer

(2016) Howard I. Scher et al.   JAMA Oncology

Critical Parameters for Efficient Sonication and Improved Chromatin Immunoprecipitation of High Molecular Weight Proteins

(2016) Nikolay A. Pchelintsev et al.   PLoS One

Androgen Receptor Splice Variants Dimerize to Transactivate Target Genes

(2015) D. Xu et al.   CANCER RESEARCH

The Cistrome and Gene Signature of Androgen Receptor Splice Variants in Castration Resistant Prostate Cancer Cells

(2015) Ji Lu et al.   JOURNAL OF UROLOGY

Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies

(2015) Siu Chiu Chan et al.   NUCLEIC ACIDS RESEARCH

Protein phosphatase 1 suppresses androgen receptor ubiquitylation and degradation

(2015) Xiaming Liu et al.   Oncotarget

Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy

(2015) Bo Cao et al.   Oncotarget

Rapid Induction of Androgen Receptor Splice Variants by Androgen Deprivation in Prostate Cancer

(2014) Z. Yu et al.   CLINICAL CANCER RESEARCH

Abiraterone Treatment in Castration-Resistant Prostate Cancer Selects for Progesterone Responsive Mutant Androgen Receptors

(2014) E. J. Chen et al.   CLINICAL CANCER RESEARCH

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

(2014) Emmanuel S. Antonarakis et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mechanisms of the androgen receptor splicing in prostate cancer cells

(2013) L L Liu et al.   ONCOGENE

Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cell Lines

(2012) Y. Li et al.   CANCER RESEARCH

Androgen Receptor Splice Variants Activate Androgen Receptor Target Genes and Support Aberrant Prostate Cancer Cell Growth Independent of Canonical Androgen Receptor Nuclear Localization Signal

(2012) Siu Chiu Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading Mechanism

(2011) Ty C. Voss et al.   CELL

Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

(2010) Shihua Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor

(2010) P. A. Watson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth

(2009) Z. Guo et al.   CANCER RESEARCH

Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance

(2008) S. M. Dehm et al.   CANCER RESEARCH

Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer

(2008) R. Hu et al.   CANCER RESEARCH