Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13

Clinical Significance of Androgen Receptor Splice Variant-7 mRNA Detection in Circulating Tumor Cells of Men With Metastatic Castration-Resistant Prostate Cancer Treated With First- and Second-Line Abiraterone and Enzalutamide

(2017) Emmanuel S. Antonarakis et al.   JOURNAL OF CLINICAL ONCOLOGY

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

(2017) M Ryan Corces et al.   NATURE METHODS

Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

(2016) Akash Kumar et al.   NATURE MEDICINE

Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

(2016) Himisha Beltran et al.   NATURE MEDICINE

Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting

(2016) E S Antonarakis et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Integrative Clinical Genomics of Advanced Prostate Cancer

(2015) Dan Robinson et al.   CELL

Cotargeting Androgen Receptor Splice Variants and mTOR Signaling Pathway for the Treatment of Castration-Resistant Prostate Cancer

(2015) M. Kato et al.   CLINICAL CANCER RESEARCH

Clinical Relevance of Androgen Receptor Splice Variants in Castration-Resistant Prostate Cancer

(2015) Benjamin L. Maughan et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

The Cistrome and Gene Signature of Androgen Receptor Splice Variants in Castration Resistant Prostate Cancer Cells

(2015) Ji Lu et al.   JOURNAL OF UROLOGY

The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis

(2015) Mark M Pomerantz et al.   NATURE GENETICS

Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies

(2015) Siu Chiu Chan et al.   NUCLEIC ACIDS RESEARCH

Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer

(2015) Zhong Chen et al.   Nature Communications

Constitutively Active AR-V7 Plays an Essential Role in the Development and Progression of Castration-Resistant Prostate Cancer

(2015) Yuanyuan Qu et al.   Scientific Reports

Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer

(2014) Z. Chen et al.   EMBO JOURNAL

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

(2014) Emmanuel S. Antonarakis et al.   NEW ENGLAND JOURNAL OF MEDICINE

Abstract 3457: Galectin-1 suppression enhances combined anti-EGFR and radiation-therapy of NSCLC

(2012) Michael Siedow et al.   CANCER RESEARCH

Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cell Lines

(2012) Y. Li et al.   CANCER RESEARCH

Germline Mutations inHOXB13and Prostate-Cancer Risk

(2012) Charles M. Ewing et al.   NEW ENGLAND JOURNAL OF MEDICINE

CCI-779 Inhibits Cell-Cycle G2-M Progression and Invasion of Castration-Resistant Prostate Cancer via Attenuation of UBE2C Transcription and mRNA Stability

(2011) H. Wang et al.   CANCER RESEARCH

Intragenic Rearrangement and Altered RNA Splicing of the Androgen Receptor in a Cell-Based Model of Prostate Cancer Progression

(2011) Y. Li et al.   CANCER RESEARCH

Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival

(2011) Emma Hörnberg et al.   PLoS One

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth

(2009) Z. Guo et al.   CANCER RESEARCH

The Homeodomain Protein HOXB13 Regulates the Cellular Response to Androgens

(2009) John D. Norris et al.   MOLECULAR CELL

Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer

(2008) R. Hu et al.   CANCER RESEARCH