Androgen Receptor Splice Variants Activate Androgen Receptor Target Genes and Support Aberrant Prostate Cancer Cell Growth Independent of Canonical Androgen Receptor Nuclear Localization Signal
Published 2012 View Full Article
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Title
Androgen Receptor Splice Variants Activate Androgen Receptor Target Genes and Support Aberrant Prostate Cancer Cell Growth Independent of Canonical Androgen Receptor Nuclear Localization Signal
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 23, Pages 19736-19749
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-04-25
DOI
10.1074/jbc.m112.352930
References
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Note: Only part of the references are listed.- AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression
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- Abiraterone and Increased Survival in Metastatic Prostate Cancer
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- Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival
- (2011) Emma Hörnberg et al. PLoS One
- A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities
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- A 629RKLKK633 motif in the hinge region controls the androgen receptor at multiple levels
- (2010) Tamzin M. Tanner et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
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- Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
- (2010) P. A. Watson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth
- (2009) Z. Guo et al. CANCER RESEARCH
- Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer
- (2009) Qianben Wang et al. CELL
- Starving the Addiction: New Opportunities for Durable Suppression of AR Signaling in Prostate Cancer
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- Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance
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- Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer
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- Structural basis for the nuclear import of the human androgen receptor
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- (2008) David F. Smith et al. MOLECULAR ENDOCRINOLOGY
- The multiple lives of NMD factors: balancing roles in gene and genome regulation
- (2008) Olaf Isken et al. NATURE REVIEWS GENETICS
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