A detailed characterization of stepwise activation of the androgen receptor variant 7 in prostate cancer cells

AR phosphorylation and CHK2 kinase activity regulates IR-stabilized AR–CHK2 interaction and prostate cancer survival

(2020) Huy Q Ta et al.   eLife

A positive role of c-Myc in regulating androgen receptor and its splice variants in prostate cancer

(2019) Shanshan Bai et al.   ONCOGENE

ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer

(2019) Laura Cato et al.   CANCER CELL

Clinical Utility of Circulating Tumour Cell Androgen Receptor Splice Variant-7 Status in Metastatic Castration-resistant Prostate Cancer

(2019) Adam Sharp et al.   EUROPEAN UROLOGY

A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities

(2019) Evangelia Kounatidou et al.   NUCLEIC ACIDS RESEARCH

Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer

(2019) Ian D. Davis et al.   NEW ENGLAND JOURNAL OF MEDICINE

Circular RNAs add diversity to androgen receptor isoform repertoire in castration-resistant prostate cancer

(2019) Subing Cao et al.   ONCOGENE

Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer

(2018) Maha Hussain et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metastatic Prostate Cancer

(2018) Oliver Sartor et al.   NEW ENGLAND JOURNAL OF MEDICINE

Androgen receptor splice variants bind to constitutively open chromatin and promote abiraterone-resistant growth of prostate cancer

(2018) Yundong He et al.   NUCLEIC ACIDS RESEARCH

Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13

(2018) Zhong Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer

(2018) Ling Cai et al.   MOLECULAR CELL

Identification of an oncogenic network with prognostic and therapeutic value in prostate cancer

(2018) Fiorella Magani et al.   Molecular Systems Biology

Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer

(2018) Adam Sharp et al.   JOURNAL OF CLINICAL INVESTIGATION

AR-V7 Transcripts in Whole Blood RNA of Patients with Metastatic Castration Resistant Prostate Cancer Correlate with Response to Abiraterone Acetate

(2017) Tilman Todenhöfer et al.   JOURNAL OF UROLOGY

Abiraterone in Metastatic Prostate Cancer

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

Enzalutamide in castration-resistant prostate cancer patients with visceral disease in the liver and/or lung: Outcomes from the randomized controlled phase 3 AFFIRM trial

(2016) Yohann Loriot et al.   CANCER

Emerging data on androgen receptor splice variants in prostate cancer

(2016) Subing Cao et al.   ENDOCRINE-RELATED CANCER

Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer

(2016) Jonathan Welti et al.   EUROPEAN UROLOGY

Interplay between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediates Castration Resistance

(2016) Yang Zhan et al.   MOLECULAR CANCER RESEARCH

Systematic and functional characterization of novel androgen receptor variants arising from alternative splicing in the ligand-binding domain

(2016) T Uo et al.   ONCOGENE

Association of AR-V7 on Circulating Tumor Cells as a Treatment-Specific Biomarker With Outcomes and Survival in Castration-Resistant Prostate Cancer

(2016) Howard I. Scher et al.   JAMA Oncology

Androgen Receptor Splice Variants Dimerize to Transactivate Target Genes

(2015) D. Xu et al.   CANCER RESEARCH

Integrative Clinical Genomics of Advanced Prostate Cancer

(2015) Dan Robinson et al.   CELL

The Cistrome and Gene Signature of Androgen Receptor Splice Variants in Castration Resistant Prostate Cancer Cells

(2015) Ji Lu et al.   JOURNAL OF UROLOGY

Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies

(2015) Siu Chiu Chan et al.   NUCLEIC ACIDS RESEARCH

Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells

(2015) Ayesha A. Shafi et al.   Oncotarget

Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy

(2015) Bo Cao et al.   Oncotarget

Androgen receptor and its splice variant, AR-V7, differentially regulate FOXA1 sensitive genes in LNCaP prostate cancer cells

(2014) William C. Krause et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

(2014) Emmanuel S. Antonarakis et al.   NEW ENGLAND JOURNAL OF MEDICINE

NF- B2/p52 Induces Resistance to Enzalutamide in Prostate Cancer: Role of Androgen Receptor and Its Variants

(2013) N. Nadiminty et al.   MOLECULAR CANCER THERAPEUTICS

Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis

(2013) X Yuan et al.   ONCOGENE

TALEN-engineered AR gene rearrangements reveal endocrine uncoupling of androgen receptor in prostate cancer

(2013) M. D. Nyquist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer

(2012) R. Hu et al.   CANCER RESEARCH

Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cell Lines

(2012) Y. Li et al.   CANCER RESEARCH

Androgen Receptor Splice Variants Activate Androgen Receptor Target Genes and Support Aberrant Prostate Cancer Cell Growth Independent of Canonical Androgen Receptor Nuclear Localization Signal

(2012) Siu Chiu Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stepwise androgen receptor dimerization

(2012) M. E. van Royen et al.   JOURNAL OF CELL SCIENCE

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants

(2011) Elahe A. Mostaghel et al.   CLINICAL CANCER RESEARCH

Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy

(2011) Changmeng Cai et al.   ENDOCRINE-RELATED CANCER

Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival

(2011) Emma Hörnberg et al.   PLoS One

A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities

(2011) Rong Hu et al.   PROSTATE

Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

(2010) Shihua Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor

(2010) P. A. Watson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth

(2009) Z. Guo et al.   CANCER RESEARCH

Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance

(2008) S. M. Dehm et al.   CANCER RESEARCH

Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer

(2008) R. Hu et al.   CANCER RESEARCH