Inhibition of ribosomal RNA processing 15 Homolog (RRP15), which is overexpressed in hepatocellular carcinoma, suppresses tumour growth via induction of senescence and apoptosis

Enhancing Glycolysis Protects against Ischemia-Reperfusion Injury by Reducing ROS Production

(2020) Claudia Beltran et al.   Metabolites

The Role of the Pentose Phosphate Pathway in Diabetes and Cancer

(2020) Tongxin Ge et al.   Frontiers in Endocrinology

The role of MDM2–p53 axis dysfunction in the hepatocellular carcinoma transformation

(2020) Hui Cao et al.   Cell Death Discovery

Hepatocellular Carcinoma

(2019) Augusto Villanueva   NEW ENGLAND JOURNAL OF MEDICINE

SIRT3 elicited an anti‐Warburg effect through HIF1α/PDK1/PDHA1 to inhibit cholangiocarcinoma tumorigenesis

(2019) Lei Xu et al.   Cancer Medicine

Proton pump inhibitor pantoprazole inhibits gastric cancer metastasis via suppression of telomerase reverse transcriptase gene expression

(2019) Bin Zhang et al.   CANCER LETTERS

Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma

(2019) Qiang Gao et al.   CELL

WNT5B exerts oncogenic effects and is negatively regulated by miR-5587-3p in lung adenocarcinoma progression

(2019) Qun Zhang et al.   ONCOGENE

LncRNA PDIA3P interacts with c-Myc to regulate cell proliferation via induction of pentose phosphate pathway in multiple myeloma

(2018) Xiangchou Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Epidemiology and Management of Hepatocellular Carcinoma

(2018) Laura Kulik et al.   GASTROENTEROLOGY

Ribosome assembly coming into focus

(2018) Sebastian Klinge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA-binding protein RPS3 contributes to hepatocarcinogenesis by post-transcriptionally up-regulating SIRT1

(2018) Lijun Zhao et al.   NUCLEIC ACIDS RESEARCH

Elevated PRC1 in gastric carcinoma exerts oncogenic function and is targeted by piperlongumine in a p53-dependent manner

(2017) Bin Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The CCCTC-binding factor (CTCF)-forkhead box protein M1 axis regulates tumour growth and metastasis in hepatocellular carcinoma

(2017) Bin Zhang et al.   JOURNAL OF PATHOLOGY

PRC1 contributes to tumorigenesis of lung adenocarcinoma in association with the Wnt/β-catenin signaling pathway

(2017) Ping Zhan et al.   Molecular Cancer

Upregulation of UBE2Q1 via gene copy number gain in hepatocellular carcinoma promotes cancer progression through β-catenin-EGFR-PI3K-Akt-mTOR signaling pathway

(2017) Bin Zhang et al.   MOLECULAR CARCINOGENESIS

Ribosomal protein S15a promotes tumor angiogenesis via enhancing Wnt/β-catenin-induced FGF18 expression in hepatocellular carcinoma

(2017) Pengyi Guo et al.   ONCOGENE

The roles of RRP15 in nucleolar formation, ribosome biogenesis and checkpoint control in human cells

(2017) Zhixiong Dong et al.   Oncotarget

Cancer metabolism: a therapeutic perspective

(2016) Ubaldo E. Martinez-Outschoorn et al.   Nature Reviews Clinical Oncology

Rrp15 affects cell cycle, proliferation, and apoptosis in NIH3T3 cells

(2016) Tao Wu et al.   FEBS Open Bio

Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine

(2015) Eric C. Cheung et al.   GENES & DEVELOPMENT

The pentose phosphate pathway and cancer

(2014) Krushna C. Patra et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Complexity of Human Ribosome Biogenesis Revealed by Systematic Nucleolar Screening of Pre-rRNA Processing Factors

(2013) Lionel Tafforeau et al.   MOLECULAR CELL

Hepatitis B virus X protein and c-Myc cooperate in the upregulation of ribosome biogenesis and in cellular transformation

(2012) Surendra Kumar Shukla et al.   FEBS Journal

Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma

(2012) Yuanyuan Ruan et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional interplay between p53 acetylation and H1.2 phosphorylation in p53-regulated transcription

(2012) K Kim et al.   ONCOGENE

Sirtuin 1 Is Upregulated in a Subset of Hepatocellular Carcinomas where It Is Essential for Telomere Maintenance and Tumor Cell Growth

(2011) J. Chen et al.   CANCER RESEARCH

Oxidative Phosphorylation as a Target to Arrest Malignant Neoplasias

(2011) Sara Rodriguez-Enriquez et al.   CURRENT MEDICINAL CHEMISTRY

A Deacetylase-Deficient SIRT1 Variant Opposes Full-Length SIRT1 in Regulating Tumor Suppressor p53 and Governs Expression of Cancer-Related Genes

(2011) Z. H. Shah et al.   MOLECULAR AND CELLULAR BIOLOGY

An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction

(2010) Everardo Macias et al.   CANCER CELL

Increased Lipogenesis, Induced by AKT-mTORC1-RPS6 Signaling, Promotes Development of Human Hepatocellular Carcinoma

(2010) Diego F. Calvisi et al.   GASTROENTEROLOGY

Activation of Ribosomal RNA Transcription by Hepatitis C Virus Involves Upstream Binding Factor Phosphorylation via Induction of Cyclin D1

(2009) S. Raychaudhuri et al.   CANCER RESEARCH

Gene expression profiling in hepatocellular carcinoma: upregulation of genes in amplified chromosome regions

(2008) Britta Skawran et al.   MODERN PATHOLOGY