Microglial-glucocorticoid receptor depletion alters the response of hippocampal microglia and neurons in a chronic unpredictable mild stress paradigm in female mice

Neuroendocrine, neuroinflammatory and pathological outcomes of chronic stress: A story of microglial remodeling

(2021) Katherine Picard et al.   NEUROCHEMISTRY INTERNATIONAL

Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2

(2020) Xiang Zhou et al.   NATURE NEUROSCIENCE

Sex differences in hypothalamic–pituitary–adrenal axis regulation after chronic unpredictable stress

(2020) Michelle C. Palumbo et al.   Brain and Behavior

IntelliCage as a tool for measuring mouse behavior – 20 years perspective

(2020) Anna Kiryk et al.   BEHAVIOURAL BRAIN RESEARCH

Levodopa partially rescues microglial numerical, morphological, and phagolysosomal alterations in a monkey model of Parkinson’s disease

(2020) Cynthia Lecours et al.   BRAIN BEHAVIOR AND IMMUNITY

Hypothalamus-pituitary-adrenal axis imbalance and inflammation contribute to sex differences in separation- and restraint-induced depression

(2020) Yinfeng Dong et al.   HORMONES AND BEHAVIOR

Microglial and peripheral immune priming is partially sexually dimorphic in adolescent mouse offspring exposed to maternal high-fat diet

(2020) Maude Bordeleau et al.   Journal of Neuroinflammation

Microglia: Neuroimmune-sensors of stress

(2019) Matthew G. Frank et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Combined Fluoxetine and Metformin Treatment Potentiates Antidepressant Efficacy Increasing IGF2 Expression in the Dorsal Hippocampus

(2019) Silvia Poggini et al.   NEURAL PLASTICITY

Repeated social defeat in female mice induces anxiety-like behavior associated with enhanced myelopoiesis and increased monocyte accumulation in the brain

(2019) Wenyuan Yin et al.   BRAIN BEHAVIOR AND IMMUNITY

CX3CR1-deficient microglia shows impaired signalling of the transcription factor NRF2: Implications in tauopathies

(2019) Sara Castro-Sánchez et al.   Redox Biology

Glucocorticoid receptor antagonism prevents microglia-mediated neuronal remodeling and behavioral despair following chronic unpredictable stress

(2019) Matthew J. Horchar et al.   BRAIN BEHAVIOR AND IMMUNITY

Fighting the Fire: Mechanisms of Inflammatory Gene Regulation by the Glucocorticoid Receptor

(2019) Laura Escoter-Torres et al.   Frontiers in Immunology

Antidepressive Effects of Kamishoyosan through 5-HT1AReceptor and PKA-CREB-BDNF Signaling in the Hippocampus in Postmenopausal Depression-Model Mice

(2019) Shoko Shimizu et al.   Evidence-based Complementary and Alternative Medicine

Microglial regional heterogeneity and its role in the brain

(2019) Yun-Long Tan et al.   MOLECULAR PSYCHIATRY

Selective activation of estrogen receptors α and β: Implications for depressive-like phenotypes in female mice exposed to chronic unpredictable stress

(2019) Rand S. Eid et al.   HORMONES AND BEHAVIOR

Glucocorticoid-mediated modulation of morphological changes associated with aging in microglia

(2018) Lynn van Olst et al.   AGING CELL

Stress-Induced Neuronal Colony Stimulating Factor 1 Provokes Microglia-Mediated Neuronal Remodeling and Depressive-like Behavior

(2018) Eric S. Wohleb et al.   BIOLOGICAL PSYCHIATRY

Persistent Increase in Microglial RAGE Contributes to Chronic Stress–Induced Priming of Depressive-like Behavior

(2018) Tina C. Franklin et al.   BIOLOGICAL PSYCHIATRY

Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome

(2018) Chin Wai Hui et al.   BRAIN BEHAVIOR AND IMMUNITY

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

(2018) Fabia Filipello et al.   IMMUNITY

Clinical and Genomic Crosstalk between Glucocorticoid Receptor and Estrogen Receptor α In Endometrial Cancer

(2018) Jeffery M. Vahrenkamp et al.   Cell Reports

Microglia and CNS Interleukin-1: Beyond Immunological Concepts

(2018) Xiaoyu Liu et al.   Frontiers in Neurology

Making sense of rodent models of anhedonia

(2018) Simona Scheggi et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones

(2018) Ashley L. Heck et al.   NEUROPSYCHOPHARMACOLOGY

The Influence of Microglial Elimination and Repopulation on Stress Sensitization Induced by Repeated Social Defeat

(2018) Michael D. Weber et al.   BIOLOGICAL PSYCHIATRY

Microglia shape presynaptic properties at developing glutamatergic synapses

(2018) Bernadette Basilico et al.   GLIA

Glucocorticoid receptor signaling in astrocytes is required for aversive memory formation

(2018) Magdalena Tertil et al.   Translational Psychiatry

Differential effects of chronic stress in young-adult and old female mice: cognitive-behavioral manifestations and neurobiological correlates

(2017) A Lotan et al.   MOLECULAR PSYCHIATRY

Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging

(2017) Petra Füger et al.   NATURE NEUROSCIENCE

Hypothalamic–pituitary–adrenal and hypothalamic–pituitary–gonadal axes: sex differences in regulation of stress responsivity

(2017) Mario G. Oyola et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Environmental stimuli shape microglial plasticity in glioma

(2017) Stefano Garofalo et al.   eLife

Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment

(2016) Silvia Alboni et al.   BRAIN BEHAVIOR AND IMMUNITY

Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice

(2016) Sabine Hellwig et al.   BRAIN BEHAVIOR AND IMMUNITY

Fractalkine receptor deficiency impairs microglial and neuronal responsiveness to chronic stress

(2016) Giampaolo Milior et al.   BRAIN BEHAVIOR AND IMMUNITY

Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophages

(2016) Michael L. Lehmann et al.   Journal of Neuroinflammation

Microglia across the lifespan: from origin to function in brain development, plasticity and cognition

(2016) Tuan Leng Tay et al.   JOURNAL OF PHYSIOLOGY-LONDON

TAM receptors regulate multiple features of microglial physiology

(2016) Lawrence Fourgeaud et al.   NATURE

Sex differences in the outcome of juvenile social isolation on HPA axis function in rats

(2016) M.G. Pisu et al.   NEUROSCIENCE

Neuron–Microglia Interactions in Mental Health Disorders: “For Better, and For Worse”

(2016) Eric S. Wohleb   Frontiers in Immunology

Gender Differences in Spatial Learning, Synaptic Activity, and Long-Term Potentiation in the Hippocampus in Rats: Molecular Mechanisms

(2015) Pilar Monfort et al.   ACS Chemical Neuroscience

Fluoxetine effects on molecular, cellular and behavioral endophenotypes of depression are driven by the living environment

(2015) S Alboni et al.   MOLECULAR PSYCHIATRY

Mechanisms of stress in the brain

(2015) Bruce S McEwen et al.   NATURE NEUROSCIENCE

Molecular mechanisms in the regulation of adult neurogenesis during stress

(2015) Martin Egeland et al.   NATURE REVIEWS NEUROSCIENCE

Neuroimmune mechanisms of stress: sex differences, developmental plasticity, and implications for pharmacotherapy of stress-related disease

(2015) Terrence Deak et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

Knockdown of Interleukin-1 Receptor Type-1 on Endothelial Cells Attenuated Stress-Induced Neuroinflammation and Prevented Anxiety-Like Behavior

(2014) E. S. Wohleb et al.   JOURNAL OF NEUROSCIENCE

The effects of chronic stress on hippocampal adult neurogenesis and dendritic plasticity are reversed by selective MAO-A inhibition

(2014) Mónica Morais et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Glucocorticoids Increase Excitotoxic Injury and Inflammation in the Hippocampus of Adult Male Rats

(2014) Shawn F. Sorrells et al.   NEUROENDOCRINOLOGY

Surveillance, Phagocytosis, and Inflammation: How Never-Resting Microglia Influence Adult Hippocampal Neurogenesis

(2014) Amanda Sierra et al.   NEURAL PLASTICITY

Re-establishment of Anxiety in Stress-Sensitized Mice Is Caused by Monocyte Trafficking from the Spleen to the Brain

(2013) Eric S. Wohleb et al.   BIOLOGICAL PSYCHIATRY

Potent and multiple regulatory actions of microglial glucocorticoid receptors during CNS inflammation

(2013) M Á Carrillo-de Sauvage et al.   CELL DEATH AND DIFFERENTIATION

Stress-Induced Recruitment of Bone Marrow-Derived Monocytes to the Brain Promotes Anxiety-Like Behavior

(2013) E. S. Wohleb et al.   JOURNAL OF NEUROSCIENCE

Estrogen protects against the detrimental effects of repeated stress on glutamatergic transmission and cognition

(2013) J Wei et al.   MOLECULAR PSYCHIATRY

Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis

(2013) T Kreisel et al.   MOLECULAR PSYCHIATRY

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

(2013) Tobias Goldmann et al.   NATURE NEUROSCIENCE

Antidepressant Treatment Outcome Depends on the Quality of the Living Environment: A Pre-Clinical Investigation in Mice

(2013) Igor Branchi et al.   PLoS One

The role of microglia in adult hippocampal neurogenesis

(2013) Carmelina Gemma et al.   Frontiers in Cellular Neuroscience

Chronic Stress Induced Remodeling of the Prefrontal Cortex: Structural Re-Organization of Microglia and the Inhibitory Effect of Minocycline

(2012) M. Hinwood et al.   CEREBRAL CORTEX

Effects of aging and sensory loss on glial cells in mouse visual and auditory cortices

(2012) Marie-Ève Tremblay et al.   GLIA

Deficiency of the Microglial Receptor CX3CR1 Impairs Postnatal Functional Development of Thalamocortical Synapses in the Barrel Cortex

(2012) M. Hoshiko et al.   JOURNAL OF NEUROSCIENCE

Stress and cardiovascular disease

(2012) Andrew Steptoe et al.   Nature Reviews Cardiology

Evidence that Microglia Mediate the Neurobiological Effects of Chronic Psychological Stress on the Medial Prefrontal Cortex

(2011) M. Hinwood et al.   CEREBRAL CORTEX

 -Adrenergic Receptor Antagonism Prevents Anxiety-Like Behavior and Microglial Reactivity Induced by Repeated Social Defeat

(2011) E. S. Wohleb et al.   JOURNAL OF NEUROSCIENCE

A standardized protocol for repeated social defeat stress in mice

(2011) Sam A Golden et al.   Nature Protocols

Sex differences in synaptic plasticity in stress-responsive brain regions following chronic variable stress

(2011) Eduardo F. Carvalho-Netto et al.   PHYSIOLOGY & BEHAVIOR

CX3CR1 deficiency alters hippocampal-dependent plasticity phenomena blunting the effects of enriched environment

(2011) Laura Maggi   Frontiers in Cellular Neuroscience

Central role of the brain in stress and adaptation: Links to socioeconomic status, health, and disease

(2010) Bruce S. McEwen et al.   Annals of the New York Academy of Sciences

Enhanced habit-based learning and decreased neurogenesis in the adult hippocampus in a murine model of chronic social stress

(2010) A. Ferragud et al.   BEHAVIOURAL BRAIN RESEARCH

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

(2010) Amanda Sierra et al.   Cell Stem Cell

Environmental enrichment requires adult neurogenesis to facilitate the recovery from psychosocial stress

(2010) R J Schloesser et al.   MOLECULAR PSYCHIATRY

The crucial role of pulsatile activity of the HPA axis for continuous dynamic equilibration

(2010) Stafford L. Lightman et al.   NATURE REVIEWS NEUROSCIENCE

Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?

(2010) Michael S. Fanselow et al.   NEURON

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Stress-induced neuroinflammation: mechanisms and new pharmacological targets

(2009) C.D. Munhoz et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Fractalkine and CX3CR1 regulate hippocampal neurogenesis in adult and aged rats

(2009) Adam D. Bachstetter et al.   NEUROBIOLOGY OF AGING

Chronic stress selectively reduces hippocampal volume in rats: a longitudinal magnetic resonance imaging study

(2009) Taekwan Lee et al.   NEUROREPORT

Chronic stress effects on dendritic morphology in medial prefrontal cortex: sex differences and estrogen dependence

(2009) J.E. Garrett et al.   NEUROSCIENCE

Effects of Long-Term Stress and Recovery on the Prefrontal Cortex and Dentate Gyrus in Male and Female Rats

(2008) Y. Lin et al.   CEREBRAL CORTEX

Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice

(2008) Fraser Murray et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators

(2008) Bruce S. McEwen   EUROPEAN JOURNAL OF PHARMACOLOGY

Steroid hormone receptor expression and function in microglia

(2008) Amanda Sierra et al.   GLIA

The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling

(2008) J M Bessa et al.   MOLECULAR PSYCHIATRY

Prenatal Restraint Stress Generates Two Distinct Behavioral and Neurochemical Profiles in Male and Female Rats

(2008) Anna Rita Zuena et al.   PLoS One

Corticosteroid hormones in the central stress response: Quick-and-slow

(2007) E. Ronald de Kloet et al.   FRONTIERS IN NEUROENDOCRINOLOGY