Asthma and posttraumatic stress disorder (PTSD): Emerging links, potential models and mechanisms

Meningeal γδ T Cells Regulate Anxiety-Like Behavior via IL-17a Signaling in Neurons

(2021) Kalil Alves de Lima et al.   BIOLOGICAL PSYCHIATRY

THE action of TH17 cells on blood brain barrier in multiple sclerosis and experimental autoimmune encephalomyelitis

(2020) Rodica Balasa et al.   HUMAN IMMUNOLOGY

Inflammation in Post-Traumatic Stress Disorder (PTSD): A Review of Potential Correlates of PTSD with a Neurological Perspective

(2020) Tammy D. Kim et al.   Antioxidants

Modulation of fear behavior and neuroimmune alterations in house dust mite exposed A/J mice, a model of severe asthma

(2020) I. Lewkowich et al.   BRAIN BEHAVIOR AND IMMUNITY

Epithelial barriers in allergy and asthma

(2020) Peter W. Hellings et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Post-traumatic stress disorder and serum cytokine and chemokine concentrations in patients with rheumatoid arthritis✰

(2019) P.M. Maloley et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

The Impact of Environmental Chronic and Toxic Stress on Asthma

(2019) Maggie Barnthouse et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

The Cytokines of Asthma

(2019) Bart N. Lambrecht et al.   IMMUNITY

Pollutants in the workplace: Effect on occupational asthma

(2019) Kevin J. Kelly et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Deconstructing the Gestalt: Mechanisms of Fear, Threat, and Trauma Memory Encoding

(2019) Stephanie A. Maddox et al.   NEURON

Influence du trouble stress post-traumatique sur l’asthme

(2019) Michel Underner et al.   PRESSE MEDICALE

Dissociation in Effective Treatment and Behavioral Phenotype Between Stress-Enhanced Fear Learning and Learned Helplessness

(2019) Michael A. Conoscenti et al.   Frontiers in Behavioral Neuroscience

Autonomic and Redox Imbalance Correlates With T-Lymphocyte Inflammation in a Model of Chronic Social Defeat Stress

(2019) Cassandra M. Moshfegh et al.   Frontiers in Behavioral Neuroscience

Corticosteroid signaling at the brain-immune interface impedes coping with severe psychological stress

(2019) A. Kertser et al.   Science Advances

Suppressive effects of type I angiotensin receptor antagonists, candesartan and irbesartan on allergic asthma

(2019) Mi-Jeong Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Social Defeat Modulates T Helper Cell Percentages in Stress Susceptible and Resilient Mice

(2019) Oliver Ambrée et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recruitment of central angiotensin II type 1 receptor associated neurocircuits in carbon dioxide associated fear

(2019) Andrew Winter et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Post-traumatic stress disorder and asthma risk: A nationwide longitudinal study

(2019) Yi-Hsuan Hung et al.   PSYCHIATRY RESEARCH

PTSD as a Public Mental Health Priority

(2019) Patricia Watson   Current Psychiatry Reports

Posttraumatic stress disorder and inflammation: untangling issues of bidirectionality

(2019) Jennifer A. Sumner et al.   BIOLOGICAL PSYCHIATRY

Repeated stress induces a pro-inflammatory state, increases amygdala neuronal and microglial activation, and causes anxiety in adult male rats

(2019) Soumyabrata Munshi et al.   BRAIN BEHAVIOR AND IMMUNITY

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

(2019) Caroline M. Nievergelt et al.   Nature Communications

Th17 and Cognitive Impairment: Possible Mechanisms of Action

(2019) Virginia Cipollini et al.   Frontiers in Neuroanatomy

IL-17a promotes sociability in mouse models of neurodevelopmental disorders

(2019) Michael Douglas Reed et al.   NATURE

Allergen-induced anxiety-like behavior is associated with disruption of medial prefrontal cortex - amygdala circuit

(2019) Kolsoum Dehdar et al.   Scientific Reports

Current Status of Animal Models of Posttraumatic Stress Disorder: Behavioral and Biological Phenotypes, and Future Challenges in Improving Translation

(2018) Jessica Deslauriers et al.   BIOLOGICAL PSYCHIATRY

Melatonin ameliorates cognitive memory by regulation of cAMP-response element-binding protein expression and the anti-inflammatory response in a rat model of post-traumatic stress disorder

(2018) Bombi Lee et al.   BMC NEUROSCIENCE

Distinct characteristics of hippocampal pathogenic T H 17 cells in a mouse model of depression

(2018) Eléonore Beurel et al.   BRAIN BEHAVIOR AND IMMUNITY

Th17 cells in depression

(2018) Eléonore Beurel et al.   BRAIN BEHAVIOR AND IMMUNITY

Repeated Allergen Exposure in A/J Mice Causes Steroid-Insensitive Asthma via a Defect in Glucocorticoid Receptor Bioavailability

(2018) Magda F. Serra et al.   JOURNAL OF IMMUNOLOGY

Neuroimmune Interactions: From the Brain to the Immune System and Vice Versa

(2018) Robert Dantzer   PHYSIOLOGICAL REVIEWS

Pulmonary neuroendocrine cells amplify allergic asthma responses

(2018) Pengfei Sui et al.   SCIENCE

Single-Prolonged Stress: A Review of Two Decades of Progress in a Rodent Model of Post-traumatic Stress Disorder

(2018) Michael J. Lisieski et al.   Frontiers in Psychiatry

ITGB4 deficiency in bronchial epithelial cells directs airway inflammation and bipolar disorder-related behavior

(2018) Li Han et al.   Journal of Neuroinflammation

CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature

(2018) Antoine Louveau et al.   NATURE NEUROSCIENCE

Asthma Induction During Development and Adult Lung Function, Behavior and Brain Gene Expression

(2018) Jasmine I. Caulfield et al.   Frontiers in Behavioral Neuroscience

Involvement of Innate and Adaptive Immune Systems Alterations in the Pathophysiology and Treatment of Depression

(2018) Eva M. Medina-Rodriguez et al.   Frontiers in Neuroscience

IFN-γ, IL-17A, or zonulin rapidly increase the permeability of the blood-brain and small intestinal epithelial barriers: Relevance for neuro-inflammatory diseases

(2018) Mohammed T. Rahman et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of Oxytocin on Fear Memory and Neuroinflammation in a Rodent Model of Posttraumatic Stress Disorder

(2018) Sheng-Chiang Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The CNS Immune-Privilege Goes Down the Drain(age)

(2018) Simone Brioschi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Toxicity of inhaled particulate matter on the central nervous system: neuroinflammation, neuropsychological effects and neurodegenerative disease

(2017) Yan Wang et al.   JOURNAL OF APPLIED TOXICOLOGY

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2017) Theo Vos et al.   LANCET

Posttraumatic stress disorder in the World Mental Health Surveys

(2017) K. C. Koenen et al.   PSYCHOLOGICAL MEDICINE

Using the Single Prolonged Stress Model to Examine the Pathophysiology of PTSD

(2017) Rimenez R. Souza et al.   Frontiers in Pharmacology

Posttraumatic Stress Disorder: An Immunological Disorder?

(2017) Zhewu Wang et al.   Frontiers in Psychiatry

Microglial Acid Sensing Regulates Carbon Dioxide-Evoked Fear

(2016) Lauren Larke Vollmer et al.   BIOLOGICAL PSYCHIATRY

Expansion of brain T cells in homeostatic conditions in lymphopenic Rag2−/− mice

(2016) Chang Song et al.   BRAIN BEHAVIOR AND IMMUNITY

An exploratory approach demonstrating immune skewing and a loss of coordination among cytokines in plasma and saliva of Veterans with combat-related PTSD

(2016) Zhewu Wang et al.   HUMAN IMMUNOLOGY

Effects of systemic administration of ibuprofen on stress response in a rat model of post-traumatic stress disorder

(2016) Bombi Lee et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD and Beyond

(2016) Vasiliki Michopoulos et al.   NEUROPSYCHOPHARMACOLOGY

Vagal Afferent Innervation of the Airways in Health and Disease

(2016) Stuart B. Mazzone et al.   PHYSIOLOGICAL REVIEWS

The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

(2016) G. B. Choi et al.   SCIENCE

Inflammatory Th17 Cells Express Integrin α v β 3 for Pathogenic Function

(2016) Fang Du et al.   Cell Reports

Gene networks specific for innate immunity define post-traumatic stress disorder

(2015) M S Breen et al.   MOLECULAR PSYCHIATRY

Chronic Psychological Distress as an Inducer of Microglial Activation and Leukocyte Recruitment into the Area Postrema

(2015) Alejandra Vargas-Caraveo et al.   NEUROIMMUNOMODULATION

Mediators of Initial Acute and Later Posttraumatic Stress in Youth in a PICU*

(2015) Stephanie Stowman et al.   Pediatric Critical Care Medicine

The epidemiology of traumatic event exposure worldwide: results from the World Mental Health Survey Consortium

(2015) C. Benjet et al.   PSYCHOLOGICAL MEDICINE

New aspects in fenestrated capillary and tissue dynamics in the sensory circumventricular organs of adult brains

(2015) Seiji Miyata   Frontiers in Neuroscience

Global burden of asthma among children

(2014) I. Asher et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Stress and asthma: Novel insights on genetic, epigenetic, and immunologic mechanisms

(2014) Stacy L. Rosenberg et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Increased frequency of dual-positive TH2/TH17 cells in bronchoalveolar lavage fluid characterizes a population of patients with severe asthma

(2014) Chaoyu Irvin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The effect of diesel exhaust exposure on blood-brain barrier integrity and function in a murine model

(2014) Sayeh Heidari Nejad et al.   JOURNAL OF APPLIED TOXICOLOGY

Animal Models of Allergic Airways Disease: Where Are We and Where to Next?

(2014) David G. Chapman et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Aligning mouse models of asthma to human endotypes of disease

(2014) Rebecca A. Martin et al.   RESPIROLOGY

Assessment of Plasma C-Reactive Protein as a Biomarker of Posttraumatic Stress Disorder Risk

(2014) Satish A. Eraly et al.   JAMA Psychiatry

Blood-based gene-expression predictors of PTSD risk and resilience among deployed marines: A pilot study

(2013) Stephen J. Glatt et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

ADCYAP1R1and Asthma in Puerto Rican Children

(2013) Wei Chen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

CNS-specific T cells shape brain function via the choroid plexus

(2013) Kuti Baruch et al.   BRAIN BEHAVIOR AND IMMUNITY

Inflammation and Oxidative Stress Are Elevated in the Brain, Blood, and Adrenal Glands during the Progression of Post-Traumatic Stress Disorder in a Predator Exposure Animal Model

(2013) C. Brad Wilson et al.   PLoS One

Angiotensin II's role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala

(2013) Philip L. Johnson et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Inflammatory T Helper 17 Cells Promote Depression-like Behavior in Mice

(2012) Eléonore Beurel et al.   BIOLOGICAL PSYCHIATRY

The Renin-Angiotensin Pathway in Posttraumatic Stress Disorder

(2012) Nayla M. Khoury et al.   JOURNAL OF CLINICAL PSYCHIATRY

Relationship between posttraumatic stress disorder and asthma among New York area residents exposed to the World Trade Center disaster

(2012) Yukie Shiratori et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

Biological studies of post-traumatic stress disorder

(2012) Roger K. Pitman et al.   NATURE REVIEWS NEUROSCIENCE

Are There Neurophenotypes for Asthma? Functional Brain Imaging of the Interaction between Emotion and Inflammation in Asthma

(2012) Melissa A. Rosenkranz et al.   PLoS One

Glucocorticoid sensitivity of leukocytes predicts PTSD, depressive and fatigue symptoms after military deployment: A prospective study

(2012) Mirjam van Zuiden et al.   PSYCHONEUROENDOCRINOLOGY

Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE

(2011) Veit Rothhammer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blood-Borne Angiotensin II Acts in the Brain to Influence Behavioral and Endocrine Responses to Psychogenic Stress

(2011) E. G. Krause et al.   JOURNAL OF NEUROSCIENCE

Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor

(2011) Kerry J. Ressler et al.   NATURE

Orchestrating house dust mite-associated allergy in the lung

(2011) Lisa G. Gregory et al.   TRENDS IN IMMUNOLOGY

IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease

(2011) Jarod Zepp et al.   TRENDS IN IMMUNOLOGY

Prevalence Estimates of Combat-Related Post-Traumatic Stress Disorder: Critical Review

(2010) Lisa K. Richardson et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Immunogenic dendritic cells primed by social defeat enhance adaptive immunity to influenza A virus

(2010) Nicole D. Powell et al.   BRAIN BEHAVIOR AND IMMUNITY

A short review on the psychoneuroimmunology of posttraumatic stress disorder: From risk factors to medical comorbidities

(2010) Thaddeus W.W. Pace et al.   BRAIN BEHAVIOR AND IMMUNITY

Impaired fear inhibition is a biomarker of PTSD but not depression

(2010) Tanja Jovanovic et al.   DEPRESSION AND ANXIETY

Association of airflow limitation with trauma exposure and post-traumatic stress disorder

(2010) C. Spitzer et al.   EUROPEAN RESPIRATORY JOURNAL

Social stress and asthma: The role of corticosteroid insensitivity

(2010) Angela Haczku et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulation of learning and memory by meningeal immunity: a key role for IL-4

(2010) Noël C. Derecki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

(2010) Kamran Ghoreschi et al.   NATURE

Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma

(2010) Stephane Lajoie et al.   NATURE IMMUNOLOGY

Neurobiological Basis of Failure to Recall Extinction Memory in Posttraumatic Stress Disorder

(2009) Mohammed R. Milad et al.   BIOLOGICAL PSYCHIATRY

Allergic rhinitis induces anxiety-like behavior and altered social interaction in rodents

(2009) Leonardo H. Tonelli et al.   BRAIN BEHAVIOR AND IMMUNITY

Single prolonged stress: toward an animal model of posttraumatic stress disorder

(2009) Shigeto Yamamoto et al.   DEPRESSION AND ANXIETY

Cellular mechanisms of IL-17-induced blood-brain barrier disruption

(2009) Jula Huppert et al.   FASEB JOURNAL

TH17-associated cytokines (IL-17A and IL-17F) in severe asthma

(2009) Wisam Al-Ramli et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Social Stress Enhances Allergen-Induced Airway Inflammation in Mice and Inhibits Corticosteroid Responsiveness of Cytokine Production

(2009) M. T. Bailey et al.   JOURNAL OF IMMUNOLOGY

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Neural regulation of endocrine and autonomic stress responses

(2009) Yvonne M. Ulrich-Lai et al.   NATURE REVIEWS NEUROSCIENCE

The blood–brain barrier and immune function and dysfunction

(2009) William A. Banks et al.   NEUROBIOLOGY OF DISEASE

IL-23 and Th17 Cells Enhance Th2-Cell–mediated Eosinophilic Airway Inflammation in Mice

(2008) Hidefumi Wakashin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Reducing post-traumatic anxiety by immunization

(2008) Gil M. Lewitus et al.   BRAIN BEHAVIOR AND IMMUNITY

Mouse models of allergic asthma: acute and chronic allergen challenge

(2008) A. T. Nials et al.   Disease Models & Mechanisms

Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier

(2008) Anika M. S. Hartz et al.   FASEB JOURNAL

Allergen Uptake, Activation, and IL-23 Production by Pulmonary Myeloid DCs Drives Airway Hyperresponsiveness in Asthma-Susceptible Mice

(2008) Ian P. Lewkowich et al.   PLoS One

Pharmacologic alternatives to antidepressants in posttraumatic stress disorder: A systematic review

(2008) William Berger et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Hostility is related to clusters of T-cell cytokines and chemokines in healthy men

(2008) Paula M.C. Mommersteeg et al.   PSYCHONEUROENDOCRINOLOGY

Noradrenergic dysfunction and the psychopharmacology of posttraumatic stress disorder

(2007) J. R. Strawn et al.   DEPRESSION AND ANXIETY

Trauma, PTSD, and physical health: An epidemiological study of Australian Vietnam veterans

(2007) Brian I. O'Toole et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH