Using the Single Prolonged Stress Model to Examine the Pathophysiology of PTSD

Single-Prolonged-Stress-Induced Changes in Autophagy-Related Proteins Beclin-1, LC3, and p62 in the Medial Prefrontal Cortex of Rats with Post-traumatic Stress Disorder

(2017) Shilei Zheng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Single-prolonged stress induce different change in the cell organelle of the hippocampal cells: A study of ultrastructure

(2016) JunLai Wan et al.   ACTA HISTOCHEMICA

Severe, multimodal stress exposure induces PTSD-like characteristics in a mouse model of single prolonged stress

(2016) Shane A. Perrine et al.   BEHAVIOURAL BRAIN RESEARCH

Behavioral changes over time in post-traumatic stress disorder: Insights from a rat model of single prolonged stress

(2016) Zhuoyun Wu et al.   BEHAVIOURAL PROCESSES

Traumatic stress causes distinctive effects on fear circuit catecholamines and the fear extinction profile in a rodent model of posttraumatic stress disorder

(2016) Chen-Cheng Lin et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Sex differences in hippocampal response to endocannabinoids after exposure to severe stress

(2016) Tomer Mizrachi Zer-Aviv et al.   HIPPOCAMPUS

Role of the Endoplasmic Reticulum Pathway in the Medial Prefrontal Cortex in Post-Traumatic Stress Disorder Model Rats

(2016) Lili Wen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Stress, glucocorticoids and memory: implications for treating fear-related disorders

(2016) Dominique de Quervain et al.   NATURE REVIEWS NEUROSCIENCE

Stress-Induced Increases in Levels of Caspases in the Prefrontal Cortex in a Rat Model of PTSD

(2016) J. H. Zhang et al.   NEUROPHYSIOLOGY

Escitalopram reversed the traumatic stress-induced depressed and anxiety-like symptoms but not the deficits of fear memory

(2016) Chen-Cheng Lin et al.   PSYCHOPHARMACOLOGY

Inhibiting corticosterone synthesis during fear memory formation exacerbates cued fear extinction memory deficits within the single prolonged stress model

(2015) Samantha M. Keller et al.   BEHAVIOURAL BRAIN RESEARCH

Sex differences in the single prolonged stress model

(2015) Samantha M. Keller et al.   BEHAVIOURAL BRAIN RESEARCH

Single prolonged stress induces dysfunction of endoplasmic reticulum in a rat model of post-traumatic stress disorder

(2015) BING XIAO et al.   Molecular Medicine Reports

NOX2 Mediated-Parvalbumin Interneuron Loss Might Contribute to Anxiety-Like and Enhanced Fear Learning Behavior in a Rat Model of Post-Traumatic Stress Disorder

(2015) Fang-fang Liu et al.   MOLECULAR NEUROBIOLOGY

Sexually divergent expression of active and passive conditioned fear responses in rats

(2015) Tina M Gruene et al.   eLife

Sleep alterations following exposure to stress predict fear-associated memory impairments in a rodent model of PTSD

(2015) William M. Vanderheyden et al.   EXPERIMENTAL BRAIN RESEARCH

Intra-hippocampal administration of ZIP alleviates depressive and anxiety-like responses in an animal model of posttraumatic stress disorder

(2014) Li-Li Ji et al.   Behavioral and Brain Functions

Expression of amygdala mineralocorticoid receptor and glucocorticoid receptor in the single-prolonged stress rats

(2014) Fang Han et al.   BMC NEUROSCIENCE

Effect of Glucose-Regulated Protein 94 and Endoplasmic Reticulum Modulator Caspase-12 in Medial Prefrontal Cortex in a Rat Model of Posttraumatic Stress Disorder

(2014) Dongmei Zhao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The effect of chronic phenytoin administration on single prolonged stress induced extinction retention deficits and glucocorticoid upregulation in the rat medial prefrontal cortex

(2014) Sophie A. George et al.   PSYCHOPHARMACOLOGY

Increased Neuronal Apoptosis in Medial Prefrontal Cortex is Accompanied with Changes of Bcl-2 and Bax in a Rat Model of Post-Traumatic Stress Disorder

(2013) Yana Li et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

In Search of the Trauma Memory: A Meta-Analysis of Functional Neuroimaging Studies of Symptom Provocation in Posttraumatic Stress Disorder (PTSD)

(2013) Gudrun Sartory et al.   PLoS One

Single-Prolonged Stress Induces Endoplasmic Reticulum - Dependent Apoptosis in the Hippocampus in a Rat Model of Post-Traumatic Stress Disorder

(2013) Fang Han et al.   PLoS One

Cannabinoids and traumatic stress modulation of contextual fear extinction and GR expression in the amygdala-hippocampal-prefrontal circuit

(2013) Eti Ganon-Elazar et al.   PSYCHONEUROENDOCRINOLOGY

Vorinostat ameliorates impaired fear extinction possibly via the hippocampal NMDA-CaMKII pathway in an animal model of posttraumatic stress disorder

(2013) Yasutaka Matsumoto et al.   PSYCHOPHARMACOLOGY

Severe Life Stress and Oxidative Stress in the Brain: From Animal Models to Human Pathology

(2012) Stefania Schiavone et al.   ANTIOXIDANTS & REDOX SIGNALING

Single prolonged stress disrupts retention of extinguished fear in rats

(2012) D. Knox et al.   LEARNING & MEMORY

Single prolonged stress induces changes in the expression of mineralocorticoid receptor in the medial prefrontal cortex in a rat model of post-traumatic stress disorder

(2012) JING-HUA ZHANG et al.   Molecular Medicine Reports

Dysfunction of calcium/calmodulin/CaM kinase IIα cascades in the medial prefrontal cortex in post-traumatic stress disorder

(2012) YU WEN et al.   Molecular Medicine Reports

Glucocorticoid receptors and extinction retention deficits in the single prolonged stress model

(2012) D. Knox et al.   NEUROSCIENCE

Conditioned fear stress combined with single-prolonged stress: A new PTSD mouse model

(2012) Haifeng Wang et al.   NEUROSCIENCE RESEARCH

Single prolonged stress enhances hippocampal glucocorticoid receptor and phosphorylated protein kinase B levels

(2012) Andrew L. Eagle et al.   NEUROSCIENCE RESEARCH

Stress-enhanced fear learning in rats is resistant to the effects of immediate massed extinction

(2012) Virginia A. Long et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Tools for translational neuroscience: PTSD is associated with heightened fear responses using acoustic startle but not skin conductance measures

(2011) Ebony M. Glover et al.   DEPRESSION AND ANXIETY

Neurobehavioral mechanisms of human fear generalization

(2011) Joseph E. Dunsmoor et al.   NEUROIMAGE

Decreased regional cerebral blood flow in medial prefrontal cortex during trauma-unrelated stressful imagery in Vietnam veterans with post-traumatic stress disorder

(2011) A. L. Gold et al.   PSYCHOLOGICAL MEDICINE

Fear Extinction in Traumatized Civilians with Posttraumatic Stress Disorder: Relation to Symptom Severity

(2010) Seth D. Norrholm et al.   BIOLOGICAL PSYCHIATRY

Single-Prolonged Stress Induces Apoptosis by Activating Cytochrome C/Caspase-9 Pathway in a Rat Model of Post-traumatic Stress Disorder

(2010) Bing Xiao et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Single-prolonged stress induced mitochondrial-dependent apoptosis in hippocampus in the rat model of post-traumatic stress disorder

(2010) Xiao Ming Li et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Alterations in the hippocampal glycinergic system in an animal model of posttraumatic stress disorder

(2010) Shigeto Yamamoto et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Enhanced hippocampal BDNF/TrkB signaling in response to fear conditioning in an animal model of posttraumatic stress disorder

(2010) Shiro Takei et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Impact of predatory threat on fear extinction in Lewis rats

(2010) S. Goswami et al.   LEARNING & MEMORY

Role of phosphorylated ERK in amygdala neuronal apoptosis in single-prolonged stress rats

(2010) Hao Liu   Molecular Medicine Reports

Single prolonged stress decreases glutamate, glutamine, and creatine concentrations in the rat medial prefrontal cortex

(2010) Dayan Knox et al.   NEUROSCIENCE LETTERS

Neurobiological Basis of Failure to Recall Extinction Memory in Posttraumatic Stress Disorder

(2009) Mohammed R. Milad et al.   BIOLOGICAL PSYCHIATRY

Glucocorticoids and the regulation of memory in health and disease

(2009) Dominique J.-F. de Quervain et al.   FRONTIERS IN NEUROENDOCRINOLOGY

The use of proton magnetic resonance spectroscopy in PTSD research—Meta-analyses of findings and methodological review

(2009) Anke Karl et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Expressions of Hippocampal Mineralocorticoid Receptor (MR) and Glucocorticoid Receptor (GR) in the Single-Prolonged Stress-Rats

(2008) Du Zhe et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Brief neonatal maternal separation alters extinction of conditioned fear and corticolimbic glucocorticoid and NMDA receptor expression in adult rats

(2008) Aaron A. Wilber et al.   Developmental Neurobiology

Stress and re-stress increases conditioned taste aversion learning in rats: Possible frontal cortical and hippocampal muscarinic receptor involvement

(2008) Linda Brand et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Presence and acquired origin of reduced recall for fear extinction in PTSD: Results of a twin study

(2008) Mohammed R. Milad et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Evidence for Acquired Pregenual Anterior Cingulate Gray Matter Loss from a Twin Study of Combat-Related Posttraumatic Stress Disorder

(2007) Kiyoto Kasai et al.   BIOLOGICAL PSYCHIATRY

Effects of single-prolonged stress on neurons and their afferent inputs in the amygdala

(2007) H. Cui et al.   NEUROSCIENCE

Early postnatal stress alters the extinction of context-dependent conditioned fear in adult rats

(2007) Machiko Matsumoto et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Activation of the serotonin 5-HT2C receptor is involved in the enhanced anxiety in rats after single-prolonged stress

(2007) Katsuya Harada et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR