Rapid at‐line early cell death quantification using capacitance spectroscopy

Real-time monitoring and control of CHO cell apoptosis by in situ multifrequency scanning dielectric spectroscopy

(2019) Fuduo Ma et al.   PROCESS BIOCHEMISTRY

Cytoplasmic conductivity as a marker for bioprocess monitoring: Study of Chinese hamster ovary cells under nutrient deprivation and reintroduction

(2019) Azita Fazelkhah et al.   BIOTECHNOLOGY AND BIOENGINEERING

Monitoring online biomass with a capacitance sensor during scale-up of industrially relevant CHO cell culture fed-batch processes in single-use bioreactors

(2019) S. Metze et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Multivariate data analysis of capacitance frequency scanning for online monitoring of viable cell concentrations in small-scale bioreactors

(2019) Sabrina Metze et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Dielectric Spectroscopy and Optical Density Measurement for the Online Monitoring and Control of Recombinant Protein Production in Stably Transformed Drosophila melanogaster S2 Cells

(2018) Jan Zitzmann et al.   SENSORS

Multi‐Omics Study on the Impact of Cysteine Feed Level on Cell Viability and mAb Production in a CHO Bioprocess

(2018) Amr S. Ali et al.   Biotechnology Journal

Biopharmaceutical benchmarks 2018

(2018) Gary Walsh   NATURE BIOTECHNOLOGY

Combined metabolomics and proteomics reveals hypoxia as a cause of lower productivity on scale-up to a 5000-liter CHO bioprocess

(2016) Yuanwei Gao et al.   Biotechnology Journal

The molecular weight and concentration of dextran sulfate affect cell growth and antibody production in CHO cell cultures

(2016) Jin Hyoung Park et al.   BIOTECHNOLOGY PROGRESS

Combined metabolomics and proteomics reveals hypoxia as a cause of lower productivity on scale-up to a 5000-liter CHO bioprocess

(2016) Yuanwei Gao et al.   Biotechnology Journal

Effect of Temperature Downshift on the Transcriptomic Responses of Chinese Hamster Ovary Cells Using Recombinant Human Tissue Plasminogen Activator Production Culture

(2016) Andrea Bedoya-López et al.   PLoS One

Impact of apoptosis on the on-line measured dielectric properties of CHO cells

(2015) Dénes Zalai et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Valeric acid induces cell cycle arrest at G1 phase in CHO cell cultures and improves recombinant antibody productivity

(2015) Jin Hyoung Park et al.   Biotechnology Journal

Valeric acid induces cell cycle arrest at G1 phase in CHO cell cultures and improves recombinant antibody productivity

(2015) Jin Hyoung Park et al.   Biotechnology Journal

Dielectric spectroscopy-based estimation of VCD in CHO cell culture

(2014) Hae Woo Lee et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

A novel approach for using dielectric spectroscopy to predict viable cell volume (VCV) in early process development

(2013) Brandon J. Downey et al.   BIOTECHNOLOGY PROGRESS

Evaluation of YO-PRO-1 as an early marker of apoptosis following radiofrequency ablation of colon cancer liver metastases

(2013) Sho Fujisawa et al.   CYTOTECHNOLOGY

Electrode polarization in dielectric measurements: a review

(2013) Paul Ben Ishai et al.   MEASUREMENT SCIENCE and TECHNOLOGY

Dual Role of Dextran Sulfate 5000 Da as Anti-Apoptotic and Pro-Autophagy Agent

(2012) J. Pedro Menvielle et al.   MOLECULAR BIOTECHNOLOGY

Exploring the effect of mild hypothermia on CHO cell productivity

(2011) Silvana Becerra et al.   BIOCHEMICAL ENGINEERING JOURNAL

Process control in cell culture technology using dielectric spectroscopy

(2011) C. Justice et al.   BIOTECHNOLOGY ADVANCES

NMR-based metabolomics of mammalian cell and tissue cultures

(2011) Nelly Aranibar et al.   JOURNAL OF BIOMOLECULAR NMR

Growth factor withdrawal in combination with sodium butyrate addition extends culture longevity and enhances antibody production in CHO cells

(2011) Jong Kwang Hong et al.   JOURNAL OF BIOTECHNOLOGY

Strategies for the enhancement of recombinant protein production from mammalian cells by growth arrest

(2010) Kevin Sunley et al.   BIOTECHNOLOGY ADVANCES

Quantitative modeling of viable cell density, cell size, intracellular conductivity, and membrane capacitance in batch and fed-batch CHO processes using dielectric spectroscopy

(2010) Cary F. Opel et al.   BIOTECHNOLOGY PROGRESS

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

(2010) Faraaz B. Chekeni et al.   NATURE

Dextran sulfate inhibits staurosporine-induced apoptosis in Chinese hamster ovary (CHO) cells: Involvement of the mitochondrial pathway

(2010) Ying Jing et al.   PROCESS BIOCHEMISTRY

Dielectric measurement of cell death

(2008) Pareshkumar Patel et al.   ENZYME AND MICROBIAL TECHNOLOGY