Discovery of sulfadrug–pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors

New quinoxalin‐1,3,4‐oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies

(2021) Roghieh Mirzazadeh et al.   ARCHIV DER PHARMAZIE

Cholinesterases, carbonic anhydrase inhibitory properties and in silico studies of novel substituted benzylamines derived from dihydrochalcones

(2021) Akın Akıncıoğlu et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of acetylcholinesterase and carbonic anhydrase I and II enzymes

(2020) Cem Yamali et al.   BIOORGANIC CHEMISTRY

Potent Acetylcholinesterase Inhibitors: Potential Drugs for Alzheimer’s Disease

(2020) Hulya Akıncıoğlu et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

A Novel Ag-N-heterocyclic Carbene Complex Bearing the Hydroxyethyl Ligand: Synthesis, Characterization, Crystal and Spectral Structures and Bioactivity Properties

(2020) Aydin Aktas et al.   Crystals

Synthesis and antioxidant activities of phenol derivatives from 1,6-bis(dimethoxyphenyl)hexane-1,6-dione

(2020) Tekin Artunc et al.   BIOORGANIC CHEMISTRY

Novel propanolamine derivatives attached to 2-metoxifenol moiety: Synthesis, characterization, biological properties, and molecular docking studies

(2020) Hayriye Genc Bilgicli et al.   BIOORGANIC CHEMISTRY

Novel functionally substituted esters based on sodium diethyldithiocarbamate derivatives: Synthesis, characterization, biological activity and molecular docking studies

(2020) Alverdi Karimov et al.   BIOORGANIC CHEMISTRY

Synthesis and in silico studies of triazene‐substituted sulfamerazine derivatives as acetylcholinesterase and carbonic anhydrases inhibitors

(2020) Sinan Bilginer et al.   ARCHIV DER PHARMAZIE

Probing 4-(diethylamino)-salicylaldehyde-based thiosemicarbazones as multi-target directed ligands against cholinesterases, carbonic anhydrases and α-glycosidase enzymes

(2020) Sadaf Hashmi et al.   BIOORGANIC CHEMISTRY

Design, synthesis, characterization, enzymatic inhibition evaluations, and docking study of novel quinazolinone derivatives

(2020) Keyvan Pedrood et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Mono- or di-substituted imidazole derivatives for inhibition of acetylcholine and butyrylcholine esterases

(2019) Burak Kuzu et al.   BIOORGANIC CHEMISTRY

Synthesis of novel tris-chalcones and determination of their inhibition profiles against some metabolic enzymes

(2019) Serdar Burmaoglu et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Novel 2-methylimidazolium salts: Synthesis, characterization, molecular docking, and carbonic anhydrase and acetylcholinesterase inhibitory properties

(2019) Selma Bal et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization and biological evaluation of N ‐substituted triazinane‐2‐thiones and theoretical–experimental mechanism of condensation reaction

(2019) Afsun Sujayev et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Novel tribenzylaminobenzolsulphonylimine based on their pyrazine and pyridazines: Synthesis, characterization, antidiabetic, anticancer, anticholinergic, and molecular docking studies

(2019) Gulnar Mamedova et al.   BIOORGANIC CHEMISTRY

Design, synthesis, in vitro and in vivo evaluation of novel pyrrolizine-based compounds with potential activity as cholinesterase inhibitors and anti-Alzheimer's agents

(2019) Nehad Abou-Elmagd El-Sayed et al.   BIOORGANIC CHEMISTRY

Synthesis of novel β-amino carbonyl derivatives and their inhibition effects on some metabolic enzymes

(2019) Abdullah Biçer et al.   JOURNAL OF MOLECULAR STRUCTURE

The behavior of some chalcones on acetylcholinesterase and carbonic anhydrase activity

(2018) Hatice Esra Aslan et al.   DRUG AND CHEMICAL TOXICOLOGY

Synthesis, Molecular Structure, Anticancer Activity, and QSAR Study of N-(aryl/heteroaryl)-4-(1H-pyrrol-1-yl)Benzenesulfonamide Derivatives

(2018) Beata Żołnowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antioxidant and anticholinergic properties of olivetol

(2018) Parham Taslimi et al.   JOURNAL OF FOOD BIOCHEMISTRY

Pyrrole: An insight into recent pharmacological advances with structure activity relationship

(2018) Shujauddin Ahmad et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract

(2018) N. Eruygur et al.   SOUTH AFRICAN JOURNAL OF BOTANY

In vitro cytotoxic and in vivo antitumoral activities of some aminomethyl derivatives of 2,4-dihydro-3H-1,2,4-triazole-3-thiones-Evaluation of their acetylcholinesterase and carbonic anhydrase enzymes inhibition profiles

(2018) İrfan Timur et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity

(2018) Dilan Ozmen Ozgun et al.   BIOORGANIC CHEMISTRY

Carbonic anhydrase inhibitory properties of phenolic sulfonamides derived from dopamine related compounds

(2017) Hulya Göcer et al.   Arabian Journal of Chemistry

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

Antioxidant Activity, Acetylcholinesterase, and Carbonic Anhydrase Inhibitory Properties of Novel Ureas Derived from Phenethylamines

(2016) Kadir Aksu et al.   ARCHIV DER PHARMAZIE

A class of sulfonamides as carbonic anhydrase I and II inhibitors

(2016) Taner Gokcen et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides

(2016) Halise Inci Gul et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling

(2014) Mostafa M. Ghorab et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel Sulphamides and Sulphonamides Incorporating the Tetralin Scaffold as Carbonic Anhydrase and Acetylcholine Esterase Inhibitors

(2013) Akın Akıncıoğlu et al.   ARCHIV DER PHARMAZIE

Reactions of Some Furan-3-ones with 2,3-Diaminopyridine and its Derivatives

(2012) Mustafa Sacmacl et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols

(2009) Murat Şentürk et al.   BIOORGANIC & MEDICINAL CHEMISTRY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Structural stability, C–N internal rotations and vibrational spectral analysis of non-planar phenylurea and phenylthiourea

(2008) Hassan M. Badawi   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY