Loss of balance between protective and pro-inflammatory synovial tissue T-cell polyfunctionality predates clinical onset of rheumatoid arthritis

Serum miRNA Signature in Rheumatoid Arthritis and “At-Risk Individuals”

(2021) Clare C. Cunningham et al.   Frontiers in Immunology

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

(2020) Yanchun Peng et al.   NATURE IMMUNOLOGY

Succinyl-CoA Ligase Deficiency in Pro-inflammatory and Tissue-Invasive T Cells

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Association of synovial tissue polyfunctional T-cells with DAPSA in psoriatic arthritis

(2019) Sarah M Wade et al.   ANNALS OF THE RHEUMATIC DISEASES

IL-4 receptor engagement in human neutrophils impairs their migration and extracellular trap formation

(2019) Daniela Impellizzieri et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Increased T cell plasticity with dysregulation of T follicular helper, T peripheral helper and T regulatory cell responses in children with JIA and Down syndrome‐associated arthritis

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A deeper understanding of intestinal organoid metabolism revealed by combining fluorescence lifetime imaging microscopy (FLIM) and extracellular flux analyses

(2019) Irina A. Okkelman et al.   Redox Biology

T Follicular Helper Cells in Autoimmune Disorders

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Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements

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Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells

(2017) Sharee A. Basdeo et al.   JOURNAL OF IMMUNOLOGY

CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression

(2017) Yanxia Guo et al.   JOURNAL OF IMMUNOLOGY

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

(2017) Deepak A. Rao et al.   NATURE

Synovial Immunophenotype and Anti-Citrullinated Peptide Antibodies in Rheumatoid Arthritis Patients

(2017) Carl Orr et al.   Arthritis & Rheumatology

Single-cell multiplexed cytokine profiling of CD19 CAR-T cells reveals a diverse landscape of polyfunctional antigen-specific response

(2017) Qiong Xue et al.   Journal for ImmunoTherapy of Cancer

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

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Induction of Th1-Biased T Follicular Helper (Tfh) Cells in Lymphoid Tissues during Chronic Simian Immunodeficiency Virus Infection Defines Functionally Distinct Germinal Center Tfh Cells

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FlowSOM: Using self-organizing maps for visualization and interpretation of cytometry data

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Polyfunctional, Pathogenic CD161+Th17 Lineage Cells Are Resistant to Regulatory T Cell–Mediated Suppression in the Context of Autoimmunity

(2015) Sharee A. Basdeo et al.   JOURNAL OF IMMUNOLOGY

Analysis of CD4+CD8+double-positive T cells in blood, cerebrospinal fluid and multiple sclerosis lesions

(2014) A. Waschbisch et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CD4+ /CD8+ double-positive T cells: more than just a developmental stage?

(2014) Nana H. Overgaard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis

(2014) Joshua K Salabei et al.   Nature Protocols

Peripheral CD4CD8 Double Positive T Cells with a Distinct Helper Cytokine Profile Are Increased in Rheumatoid Arthritis

(2014) Dagmar Quandt et al.   PLoS One

Decreased Frequencies of Circulating Follicular Helper T Cell Counterparts and Plasmablasts in Ankylosing Spondylitis Patients Naïve for TNF Blockers

(2014) María-Belén Bautista-Caro et al.   PLoS One

Optical Metabolic Imaging Identifies Glycolytic Levels, Subtypes, and Early-Treatment Response in Breast Cancer

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The who's who of T-cell differentiation: Human memory T-cell subsets

(2013) Yolanda D. Mahnke et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Characterization of metabolic changes associated with the functional development of 3D engineered tissues by non-invasive, dynamic measurement of individual cell redox ratios

(2012) Kyle P. Quinn et al.   BIOMATERIALS

Polyfunctional responses by human T cells result from sequential release of cytokines

(2011) Q. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synovial tissue hypoxia and inflammation in vivo

(2010) C. T. Ng et al.   ANNALS OF THE RHEUMATIC DISEASES

CD4+ T Cell Plasticity—Th2 Cells Join the Crowd

(2010) Jinfang Zhu et al.   IMMUNITY

GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity

(2009) Aya Yokota et al.   INTERNATIONAL IMMUNOLOGY